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Found 53 clinical trials
Breaking Bad News - Optimizing Stress Response and Communication Performance in Medical Students (BPSM)

Breaking bad news (e.g., telling patients that they have cancer) is not only very stressful for the patients concerned, but also for the physicians delivering the diagnosis. It is unclear how this burden and the associated communication performance can be optimized. The project contributes to this goal. The main goal …

Accepts healthy volunteers
  • 06 Jun, 2022
  • 1 location
Randomized Controlled Trial for Comparison of the Effects of Preventing Postoperative Pancreatic Fistula by With Versus Without TissePatchTM Cover the Wound Surface of Pancreatic Capsule

Postoperative pancreatic fistula is one of the most serious complications after gastric cancer surgery and can lead to surgery-related death. Postoperative pancreatic fistula for gastric cancer often occurs in accidental injury of pancreas during peripancreatic lymph node dissection, blunt separation of pancreatic capsule injury, laparoscopic instrument clamp and long-term compression …

  • 20 Sep, 2022
  • 1 location
Regular vs. Clear Liquid Diet for Mild to Moderate Acute Pancreatitis

Acute pancreatitis is among the most common gastroenterology diagnosis in the United States, and represents a large economic burden to the United States health system. While recent guidelines agree early feeding shortens length of stay, these guidelines fail to provide recommendations on optimal diet to start leaving diet type to …

acute pancreatitis
Accepts healthy volunteers
abdominal pain
  • 27 Dec, 2021
  • 1 location
Helping Stroke Patients With ThermoSuit Cooling (SISCO)

The aim of this study is to assess the feasibility of using the Life Recovery Systems ThermoSuit Device to induce therapeutic hypothermia (32-34°C) in victims of ischemic stroke. This feasibility clinical study will enroll a total of 30 patients with acute ischemic stroke at four clinical centers. Subjects will receive …

ischemic stroke
  • 22 Jul, 2022
  • 3 locations
Efficacy of Energy Therapy in the Management of Chronic Pain Medical Condition in Children and Adolescents. (ET&CP)

Paediatric and adolescent patients with chronic pain associated with their medical condition will be invited to participate in this study. Most patients for this study will be recruited from gastroenterology and hepatology clinics at KCH. Therefore the rationale for the study is primarily with consideration of each of these medical …

ulcerative colitis
inflammatory bowel disease
crohn's disease
  • 04 Jun, 2022
  • 1 location
Fecal Microbiota Therapy in Steroid Ineligible Alcoholic Hepatitis

Alcoholic hepatitis, the most florid form of alcoholic liver disease, has a very high short-term mortality of up to 50% and no specific therapies are available other than steroids. Steroids also only show a limited utility in improving the short-term survival and boast no evidence of any long-term benefits. Additionally, …

liver disease
  • 30 Apr, 2022
  • 1 location
Yoga Practice, Stress and Cognitive Performance

It has been indicated in recent research that Mindfulness-based interventions may offer possibilities of promoting human stress processing and reducing anxiety or depression. They also appear to positively influence cognitive performance. One mindfulness-based intervention next to a variety of others is yoga, a combination of physical, spiritual, and mental practices …

Accepts healthy volunteers
  • 23 Mar, 2022
  • 1 location
A Study of Pembrolizumab and Bavituximab in Patients With Advanced Hepatocellular Carcinoma

This is a non-randomized, open-label, multi-site phase II therapeutic trial of pembrolizumab and bavituximab in patients with locally advanced HCC. Locally advanced or metastatic HCC is defined as disease that is not amenable to surgical and/or locoregional therapies. Subjects must not have received prior systemic therapy for advanced HCC in …

hepatitis b surface antigen
platelet count
antiviral therapy
  • 13 May, 2022
  • 1 location
Total pancrEaTectomy vs High-Risk Pancreatic anastomosiS (TETRIS)

Postoperative pancreatic fistula (POPF) is the main driver of surgical morbidity after pancreatoduodenectomy (PD). The aim of the present study is to compare total pancretectomy (TP) and primary pancreatic anastomosis (PA) in a cohort of extremely high-risk patients, with regards to postoperative outcomes and quality of life (QoL).

  • 23 Mar, 2022
Safety and Tolerability of Intravenous Fish Oil Lipid Emulsion in Children Undergoing Hematopoietic Cell Transplantation

Children undergoing hematopoietic cell transplantation (HCT) for cancer or blood disorders frequently develop gastrointestinal, metabolic and infectious complications related to preparative high-dose chemotherapy and/or radiation-related toxicity. Parenteral nutrition (PN) with lipid emulsion is commonly required while gastrointestinal complications preclude adequate oral or enteral intake. PN and lipids may increase the …

nutritional care
fish oil
hematologic malignancy
transplant conditioning
  • 29 Jun, 2022
  • 1 location