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Found 52 clinical trials
The Interplay Between Addiction to Tobacco Smoking and Sleep Quality Among Healthy Adults

polysomnography (PSG), pulmonary function test, biological markers of stress (cortisol and -amylase) and smoking (i.e., cotinine, the main metabolite of nicotine), and emotional and cognitive functioning via

nicotine dependence
amylase
polysomnography
nicotine product
psychiatric disorder
  • 73 views
  • 26 Feb, 2022
  • 1 location
Social Stress and Suicide (SUPHY)

Only vulnerable patients, when facing environmental stressors, attempt or commit suicide. Previous research demonstrated that suicide attempters usually misunderstand the social context and show impairments in decision making. Heart activity, endocrine and inflammatory response to stress were related with these features. For that, suicide attempters, in a context of social …

  • 0 views
  • 22 Mar, 2022
  • 1 location
Trans-drain Occlusion for Postoperative Pancreatic Fistula- A Double Blind Randomized Clinical Trial

This is a multicenter, investigator initiated, prospective, superiority, parallel-group, randomized, double-blinded trial that aims to compare the efficacy and safety of trans-drain occlusion followed by gradual withdrawal of drain versus gradual withdrawal of drain alone for postoperative pancreatic fistula (POPF) that persists for longer than 21 days.

  • 0 views
  • 19 Aug, 2021
  • 1 location
Personalized Obesity Management - Matching Dietary Fibers and Microbial Enterotype (POMFAME)

The overall aim of this 12-week randomized controlled trial is to investigate if a dietary fiber supplement rich in arabinoxylans (AX) affects weight loss success differently according to baseline gut microbiota composition in subjects who have overweight or obesity. 105 participants will be randomized in a 2:1 ratio to receive …

Accepts healthy volunteers
  • 23 views
  • 03 Jun, 2022
  • 1 location
Evaluation of Pancreatic Cystic Lesions Via EUS-guided Fine Needle Aspiration With and Without Micro Forceps Biopsies

Pancreatic cystic lesions (PCLs) are a common incidental finding in cross sectional imaging (up to 27% on CT scan and 41% on MRI) and pose a management challenge to physicians. According to society guidelines, PCLs with specific features should prompt additional workup with endoscopic ultrasound (EUS) for cyst characterization as …

  • 0 views
  • 16 Dec, 2021
  • 1 location
Interest of the Sialendoscopy Associated With a Local Injection of Corticosteroids in the Treatment of Radio-induced Xerostomia in Comparison With the Hygiene Rules

Xerostomia is defined as the subjective sensation of dry mouth, and may be associated with a reduction in saliva secretion and composition. It is one of the most common complaints found in patients after irradiation in the head and neck area. This complaint is found in a large majority of …

  • 0 views
  • 05 Jan, 2022
  • 1 location
Effects of Microbial Enzyme Supplementation on Postprandial Nutrient Levels and Gastrointestinal Symptoms in Healthy Middle-Aged and Older Adults (BIO-3003)

The primary objective of this study is to investigate the acute effects of a microbial multi-enzyme mixture ("BC-006") on postprandial nutrient levels in healthy, middle-aged to older adults during a mixed meal tolerance test. Additionally, the effects of twice daily consumption of BC-006 and placebo for 3 weeks on abdominal …

Accepts healthy volunteers
  • 0 views
  • 23 Jul, 2022
  • 1 location
Acute Effects of Physical Exercise in Patients With Borderline Personality Disorder

The aim of the proposed project is to investigate the effects of a single session of physical exercise on stress regulation, cognitive and emotional functioning, and associated neurophysiological processes (saliva and blood samples) in patients with borderline personality disorder. A further aim is to identify the optimal exercise intensity (moderate …

Accepts healthy volunteers
  • 0 views
  • 25 Mar, 2022
  • 1 location
Dementia and Diabetes Prevention Program (DDPP)

This is a multicenter, randomized 2-arm clinical trial of two lifestyle interventions varying in intensity and format, in 400 older African American and non-Hispanic whites at increased risk of cognitive decline and dementia in the East San Francisco Bay Area. The trial will include two lifestyle interventions that differ in …

diabetes prevention
hypertension
cognitive impairment
cognitive decline
dementia
  • 9 views
  • 23 Mar, 2022
  • 1 location
Breaking Bad News - Optimizing Stress Response and Communication Performance in Medical Students (BPSM)

Breaking bad news (e.g., telling patients that they have cancer) is not only very stressful for the patients concerned, but also for the physicians delivering the diagnosis. It is unclear how this burden and the associated communication performance can be optimized. The project contributes to this goal. The main goal …

Accepts healthy volunteers
  • 0 views
  • 06 Jun, 2022
  • 1 location