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Found 62 clinical trials
Initial Management of MRONJ Stages I and II a Clinical Trial With Detection of Salivary Biomarkers

Medication-related osteonecrosis of the jaw (MRONJ) is a serious complication in patients receiving antiresorptive therapies, such as Bisphosphonates and Denosumab. It is defined by the presence of exposed bone or a fistula that probes bone in the jaws for a period greater than 8 weeks in patient with a history …

  • 0 views
  • 24 Feb, 2021
  • 1 location
Digital Occlusal Wafer Versus Waferless Distal Segment Repositioning for BSSO in Skeletal Mandibular Deformities

Research studies continues to attempt testing modifications to refine the treatment protocols through computer assisted design or computer-generated surgical Wafer splints, have greatly revolutionized the incorporation of digital imaging and 3D design in Orthognathic surgery. Integrating computer guided technology in orthognathic surgery aims to to simplify workup and reduce surgical …

Accepts healthy volunteers
  • 0 views
  • 15 Dec, 2021
  • 1 location
Acquisition of Resistant Enterobacteria During Oral Drug Challenge for Betalactams in Children

Direct drug provocation testing, without prior skin or in vitro testing, is the reference standard for confirming the diagnosis of drug hypersensitivity reactions in children reporting mild and delayed-onset reactions. However, optimal protocol(s) have not been standardized. Although a 2-days' provocation testing protocol is effective, increasing its duration (up to …

  • 0 views
  • 27 May, 2021
  • 1 location
Abdominal Diastasis Repair by Robotic Surgery (PROMA1)

The objective of the study is to evaluate the feasibility of a robot-assisted minimally invasive surgical technique for the management of diastasis of the rectus abdominis. The effectiveness of this robotic surgery will be evaluated on the intermuscular distance measurement above and under umbilicus using ultrasound or CT-scan imaging.

  • 0 views
  • 09 Apr, 2022
  • 1 location
The OPTIMAL TDM Study: Determining Optimal Beta-lactam Plasma Concentrations Through Therapeutic Drug Monitoring

plasma concentrations of imipenem, meropenem, amoxicillin, flucloxacillin, piperacillin, ceftazidime and cefepime in patients at increased risk of serious bacterial infections and currently understudied

  • 0 views
  • 02 Jun, 2021
  • 1 location
European Registry on the Management of Helicobacter Pylori Infection

The great diversity of regimens and treatment lines, the different efficacy of these, mostly due to the increase in bacterial antibiotic resistance and regional differences, requires a continuous critical analysis of clinical practice, evaluating systematically the efficacy and safety of the different regimens and the cost-effectiveness of the different diagnostic-therapeutic …

antibiotic therapy
gastric cancer
peptic ulcer
antibiotics
cancer
  • 241 views
  • 07 Sep, 2021
  • 30 locations
Renal Tolerance of Amoxicillin and Cloxacillin Combination

investigator's primary purpose is to describe patients treated with high dose Amoxicillin and Cloxacillin combination and to evaluate its renal tolerance.

nephrotoxicity
  • 0 views
  • 10 Dec, 2021
  • 1 location
Antibiotic Dosing in Patients on Intermittent Hemodialysis

The adequacy of the currently used dosing regimen of glycopeptides (vancomycin and teicoplanin) and beta-lactam antibiotics (amoxicillin-clavulanic acid, piperacillin-tazobactam, ceftazidim) in

intermittent hemodialysis
  • 0 views
  • 17 Aug, 2021
  • 1 location
Antibiotic Dosing in Geriatric Patients at the Emergency Department (AGED)

In this pilot study, we will investigate whether - with the current dosing regimens, used in the Ghent University Hospital - pharmacodynamic targets regarding beta-lactam antibiotics (more specific Amoxicilline-Clavulanate, Piperacillin-Tazobactam and Temocillin) are attained in frail patients admitted to the geriatric department.

lactam antibiotics
piperacillin-tazobactam
piperacillin
antibiotic therapy
antibiotics
  • 0 views
  • 24 Mar, 2022
  • 1 location
Microbiota Implementation to Reduce Anastomotic Colorectal Leaks (MIRACLe)

Aim of this study is to implement the intestinal microbiota by perioperative administration of probiotics, oral antibiotics and low volume mechanical preparation in order to reduce the incidence of colorectal anastomotic leaks and dehiscences.

Accepts healthy volunteers
  • 0 views
  • 01 Jan, 2022
  • 1 location