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Found 15 clinical trials
To Optimize Antenatal Management of Women With Pre Term Labor Using Amniocentesis (OPTIM-PTL)

Implementation of prediction models of risk of spontaneous delivery within 7 days or of intra-amniotic infection in women with preterm labor and intact membranes

Accepts healthy volunteers
  • 0 views
  • 26 May, 2022
Realization of Sequencing of All Known Human Genes in Case of Detection of Cerebral Renal or Ophthalmological Fetal Malformations During Pregnancy in Order to Make an Etiological Diagnosis and to Precise the Fetal Prognosis

Congenital malformations concern 3% of pregnancies; most of them can be seen during pregnancy. For some malformations, an invasive sample (trophoblast biopsy or amniocentesis) is proposed to

  • 0 views
  • 26 Jan, 2021
  • 12 locations
Extended Criteria For Fetal Myelomeningocele Repair

amniocentesis. We will be extending the Management of Myelomeningocele Study (MOMs) criteria by including these factors. Prenatal clinical and outcome information will be collected; safety and

amniocentesis
prematurity
cleft lip
diabetes
prenatal
  • 24 views
  • 04 Jun, 2022
  • 2 locations
Fetal Genome Profiling Via Trophoblast Cells

The objective of this study is to utilize trophoblast cells accumulating in the endocervical canal at the beginning of pregnancy for non-invasive prenatal testing. If we are able to validate that trophoblast cells obtained at an early gestational age can be reliably used for prenatal testing, there is great potential …

early pregnancy
Accepts healthy volunteers
prenatal
  • 4 views
  • 04 Feb, 2022
  • 1 location
Natural History of Maternal Neoplasia

Background Pregnant women can get a DNA analysis of their blood. The test tells a woman and her doctor about the DNA of her unborn baby. But some women get test results that are abnormal or not reportable. Researchers want to learn more about the relationship between these test results …

Accepts healthy volunteers
  • 1 views
  • 19 Jun, 2022
  • 1 location
Biomarkers in Obstetrical Complications

, saliva, cervicovaginal fluid, gingival crevicular fluid, swabs to characterize microbiota, amniotic fluid when a clinically indicated amniocentesis is performed). Placentas will be collected at the time

amniocentesis
premature labor
microbiota
pregnancy complication
fetal death
  • 294 views
  • 19 Jun, 2022
  • 1 location
Specimen Collection From Pregnant Women at Increased Risk for Fetal Aneuploidy

The specimen collection is designed for the purpose of the development of a noninvasive prenatal test for T21.

amniocentesis
prenatal
  • 116 views
  • 30 Jan, 2022
  • 10 locations
Mineral Status in Pregnant Women (PREDISH)

Ensuring an adequate supply of nutrients, which include trace elements, is particularly important in pregnancy. Both deficiency and excess of trace elements in the body can interfere with conception and maintaining a healthy pregnancy. The effects of malnutrition and shortages in fetal life may increase the risk of miscarriages, congenital …

Accepts healthy volunteers
  • 4 views
  • 22 Apr, 2022
  • 1 location
Scottish Advanced Fetal Research Study (SAFeR)

In-utero exposure to drugs and chemicals through maternal smoking, alcohol use, drug abuse, prescription medicines and occupational/lifestyle exposures is widespread. Such exposures can alter fetal development and programming, leading to the effects becoming "locked in" from birth and causing long-term adverse consequences for the individual. These include costly and widespread …

Accepts healthy volunteers
  • 0 views
  • 25 May, 2022
  • 1 location
Non-invasive Placental Chromosome Exploration of Intrauterine Growth Restriction (DPNI-RCIU)

parallel with an amniocentesis. This study will allow the chromosomal study of the placenta in pregnant women whose genetic prenatal diagnosis, made by amniocentesis, does not allow exploring the

  • 0 views
  • 26 Mar, 2022
  • 1 location