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Found 8 clinical trials
A Proof of Concept Study of Pradigastat in Patients With Functional Constipation

The purpose of this study is to evaluate the efficacy, safety, and tolerability of pradigastat 20 and 40 mg as compared to placebo in patients with Functional Constipation.

  • 0 views
  • 16 May, 2021
  • 25 locations
Glutamatergic Mechanisms of Psychosis and Target Engagement (SA1)

50 healthy volunteers (HV) will participate in 2 identical ketamine-induced pharmacoBOLD (phBOLD) sessions at least 7 days apart. On both days, clinical assessments will be performed following removal of the subject from the scanner. HV will be discharged home after clearance by the study physician. This study will assign ketamine …

  • 0 views
  • 28 Jan, 2021
  • 1 location
Planning Treatment for Oesophago-gastric Cancer: a Maintenance Therapy Trial

To evaluate the efficacy of maintenance therapies following completion of standard first-line chemotherapy in patients with locally advanced or metastatic HER-2 positive or HER-2 negative oesophago-gastric adenocarcinomas.

blood transfusion
metastasis
cancer
adenocarcinoma
medi4736
  • 0 views
  • 23 Jan, 2021
  • 2 locations
Randomised Evaluation of COVID-19 Therapy

RECOVERY is a randomised trial investigating whether treatment with Lopinavir-Ritonavir, Hydroxychloroquine, Corticosteroids, Azithromycin, Colchicine, IV Immunoglobulin (children only), Convalescent plasma, Synthetic neutralizing antibodies (REGN-COV2), Tocilizumab, Aspirin, Baricitinib, Infliximab or Anakinra (children only) prevents death in patients with COVID-19.

hydroxychloroquine
lopinavir
pneumonia
corticosteroids
covid-19
  • 0 views
  • 13 May, 2021
  • 3 locations
Preoperative High-dose Dexamethasone and Emergency Laparotomy

The aim of this trial is to evaluate the effect of high-dose glucocorticoid on inflammatory response and recovery after emergency laparotomy in participants with intestinal obstruction and perforated viscus. Primary outcome is the reduction of C-reactive protein on postoperative day 1. Secondary outcomes are organ specific complications in the post …

  • 0 views
  • 20 Mar, 2021
  • 1 location
Randomized Trial of an HIV Prevention and Relationship Education Program for Young Male Couples

Young gay, bisexual, and other men who have sex with men (YMSM) are the only risk group in which rates of new HIV infections are on the rise. There has been a relative dearth of research dedicated to understanding these health disparities between gay/bisexual and heterosexual youth, and even less …

HIV Infection
hiv test
HIV Vaccine
hiv prevention
hiv testing
  • 4 views
  • 25 Jan, 2021
  • 1 location
Developing an Online Therapeutic Intervention for Chronic Pain in Veterans

Chronic pain is a serious concern that disproportionately affects Veterans compared to the general public; Veterans are diagnosed with chronic pain at particularly high rates (47 - 56%) with a 40% greater rate of severe pain than non-Veterans. Veterans with chronic pain face numerous negative functional outcomes, including decreased ability …

pain relieving
osteoarthritis
chronic pain management
chronic pain
acceptance and commitment therapy
  • 0 views
  • 04 Jun, 2021
  • 1 location
The Swiss Childhood Cancer Survivor Study - Follow-up (SCCSS-FollowUp)

The SCCSS-FollowUp is a national, multicenter cohort study designed to investigate late effects in childhood cancer survivors in a prospective and longitudinal way. The study is embedded in regular follow-up care and inclusion in the study takes place in a step-wise approach. The investigators collect data from clinical examinations, laboratory …

  • 0 views
  • 03 Feb, 2021
  • 3 locations