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Found 16 clinical trials
Changes in Glutamatergic Neurotransmission of Severe TBI Patients

)benzonitrile)-positron emission tomography ( [18F]FPEB-PET) at rest and following a short pharmacological challenge with amantadine, an N-methyl-D-aspartate receptor (NMDA-R) antagonist, following L-DOPA, and

dopamine
amantadine
  • 62 views
  • 25 Jan, 2021
Randomized Placebo Controlled Trial Evaluating the Efficacy of Pimavanserin a Selective Serotonin 5-HydroxyTryptamine-2A (5HT2A) Inverse Agonist to Treat Impulse Control Disorders in Parkinson's Disease.

amantadine in pathological gambling is controversial and the efficacy of clozapine has been reported in a few cases but with serious safety limitations. Very recently, naltrexone did not significantly

antidepressants
dopamine
impulse control disorder
parkinsonism
anticholinergic agents
  • 1 views
  • 13 May, 2021
  • 29 locations
Post-stroke Epilepsy: Primary Prophylaxis Study

Advance in stroke treatment have resulted in a dramatic reduction in the stroke mortality, however, the number of stroke survivors living with morbidity has increased significantly. As we know, post-stroke epilepsy has been identified as a significant clinical issue in stroke survivors and stroke is the most common cause of …

  • 0 views
  • 08 May, 2021
  • 1 location
Comparison of the Incidence of Dyskinesia in Parkinson's Disease Who Were Treated With Amantadine or Dopamine Agonist

The purpose of this study is to compare the onset time and severity of dyskinesia in amantadine or Dopamine agonist initial treated groups in Parkinson's disease.

dopamine
dopamine agonists
dyskinesia
amantadine
  • 1 views
  • 21 Jan, 2021
  • 1 location
Acetylamantadine Excretion by Cancer Patients

in vitro research has shown that drug acetylation activity is increased in cancer. Amantadine may be of value in detecting the presence of cancer. Accordingly, this study will examine how Amantadine

primary cancer
cancer screening
breast cancer
  • 14 views
  • 26 Mar, 2021
  • 1 location
Excretion of Acetylamantadine (AA) by Lung Cancer Patients During a Chemotherapy Regimen

This study is designed to determine if changes in acetyl amantadine (AA) metabolism with systemic chemotherapy - reflective of SSAT1 activity - are predictive of response to systemic therapy in

cancer
lung cancer
adenocarcinoma
cancer chemotherapy
lung carcinoma
  • 2 views
  • 25 Mar, 2021
  • 2 locations