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Found 1501 clinical trials
Featured trial
A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE)

This study is done to find out whether the medicine, semaglutide, has a positive effect on early Alzheimer's disease. Participants will either get semaglutide or placebo (a "dummy

mental state examination
memantine
mild dementia
acetylcholinesterase
dementia
  • 21 views
  • 22 Sep, 2022
  • 46 locations
Featured trial
An Efficacy and Safety Study of ALZ-801 in APOE4/4 Early AD Subjects

Our team of medical professionals is evaluating an investigational drug that is designed to slow the progression of Alzheimer’s disease. The study drug, ALZ-801, is a tablet that is taken twice daily. It has been well tolerated in earlier studies and may be a convenient option for Alzheimer’s patients and …

mild dementia
mini-mental state examination
apolipoprotein e
dementia
  • 76 views
  • 20 Sep, 2022
  • 79 locations
Featured trial
AHEAD 3-45 Study: A Study to Evaluate Efficacy and Safety of Treatment With BAN2401 in Participants With Preclinical Alzheimer's Disease and Elevated Amyloid and Also in Participants With Early Preclinical Alzheimer's Disease and Intermediate Amyloid

The primary purpose of this study is to determine whether treatment with BAN2401 is superior to placebo on change from baseline of the Preclinical Alzheimer Cognitive Composite 5 (PACC5) at

mental state examination
mini-mental state examination
dementia
amyloid
  • 26 views
  • 29 Aug, 2022
  • 4 locations
Featured trial
Preventing Alzheimer's With Cognitive Training (PACT)

Dementia is the most expensive medical condition in the US and increases in prevalence with age. More than 5 million Americans have Alzheimer's disease, the most common form of dementia. Mild

cognitive impairment
Accepts healthy volunteers
dementia
cognitive stimulation
mild cognitive impairment
  • 1 views
  • 28 Oct, 2022
  • 5 locations
Featured trial
A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-design Study to Assess the Efficacy, Safety, and Tolerability of AVP-786 (Deudextromethorphan Hydrobromide [d6-DM]/Quinidine Sulfate [Q]) for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type

This study will be conducted to evaluate the efficacy, safety, and tolerability of AVP-786 compared to placebo, for the treatment of agitation in participants with dementia of the Alzheimer's

dementia
agitation
  • 2 views
  • 15 Oct, 2022
  • 82 locations
Featured trial
Dementia Family Caregiver Study

The proposed study will test a 3-month, community health worker (CHW) delivered home visit, culturally and language-appropriate intervention for ethnic and underserved dementia family

alzheimer's disease
Accepts healthy volunteers
  • 27 views
  • 30 Apr, 2022
  • 1 location
Featured trial
Telerehabilitation Alzheimer's Disease Feasibility (TADF) (TADF)

This is a pilot RCT with equal arms: experimental arm and (wait list) control arm. All participants will be in the early stage of Alzheimer's disease and on stable medication. They

Accepts healthy volunteers
aricept
exelon
  • 1 views
  • 31 May, 2022
  • 1 location
Featured trial
Methodology Issues in a Tailored Light Treatment for Persons With Dementia

Tailored light treatment will increase sleep efficiency, reduce depression and reduce agitation scores in those with Alzheimer's disease and related dementia

mental state examination
depressed mood
agitation
depression
Accepts healthy volunteers
  • 6 views
  • 01 Apr, 2022
  • 2 locations
Featured trial
A Ten-Week Online Acceptance and Commitment Therapy Intervention for Family Caregivers of People With Dementia

dementia (PwD) compared to the control group. A total of 64 family caregivers of PwD who meet the inclusion criteria will be recruited and randomized to either the intervention group or the control group

depression
  • 12 views
  • 28 Oct, 2022
  • 1 location
Featured trial
  • 0 views
  • 15 Oct, 2022
  • 7 locations