Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 18 clinical trials
Pathophysiological Mechanism Behind Prolonged Whiplash Associated Disorders

The knowledge of pathophysiological mechanisms behind prolonged Whiplash Associated Disorders (WAD) is insufficient and whether changes can be restored by rehabilitation or not is unknown. The aim of these studies are to investigate different parameters to further learn about pathophysiological mechanisms (neck muscle fatty infiltration, cross-sectional area, volume, inflammation and …

  • 1 views
  • 26 Feb, 2021
  • 1 location
Helping Youth on the Path to Employment

Helping Youth on the Path to Employment (HYPE): Creating economic self-sufficiency, a randomized-controlled implementation efficacy hybrid trial, will test a manualized intervention combining educational and employment supports for young adults with mental health conditions.

  • 4 views
  • 24 Jan, 2021
  • 2 locations
RCT of Efficacy of Amoxicillin Over Ampicillin on Severe Pneumonia

Burden: Pneumonia remains the leading infectious cause of death accounting 920,000 children under five around the world. This means a loss over 2,500 child lives every day, or over 100 every hour. Since 2000, the number of child deaths caused by pneumonia has decreased by 47 per cent. The tremendous …

amoxicillin
  • 17 views
  • 17 Mar, 2021
  • 1 location
Self-management of Sedative Therapy by Ventilated Patients

The purpose of this randomized clinical trial is to test the efficacy of dexmedetomidine for the self-management of sedative therapy (SMST) in a sample of critically ill patients receiving mechanical ventilator support. The investigators hypothesis is that self-management of sedative therapy by mechanically ventilated patients in the intensive care unit …

critical illness
anxiety reduction
opioid
ketamine
sedative
  • 221 views
  • 01 May, 2021
  • 2 locations
Automated Insulin Delivery in Elderly With Type 1 Diabetes (AIDE T1D)

A multi-center, randomized, crossover trial consisting of three sequential 12-week periods, with the HCL feature used during one period, the PLGS feature used during one period and SAP therapy (control) during one period. The crossover trial will be preceded by a run-in phase in which participants will receive training using …

  • 0 views
  • 26 Apr, 2021
  • 3 locations
Acceptance and Commitment Therapy for Aging People Living With HIV in Chronic Pain

Chronic pain impacts a large proportion of aging people living with HIV (aPLWH) and involves factors directly related to HIV (neurotoxicity) and psychosocial co-morbidities common in aPLWH (i.e. social isolation and loneliness). The investigators hypothesize that novel interventions that acknowledge these psychosocial co-morbidities may improve the efficacy of chronic pain …

cancer
chronic pain management
analgesia
acceptance and commitment therapy
cancer pain
  • 45 views
  • 26 Jan, 2021
  • 1 location
Nebulized Sub-dissociative Dose Ketamine for Treating Pain

The investigators previous research study comparing the efficacy of intravenous ketamine to morphine showed ketamine to provide equivalent relief of moderate to severe acute pain in emergency department patients. A second study by the investigators showed that increasing the time of administration of the ketamine, from a push injection to …

acute pain
ketamine
cancer
pain relief
morphine
  • 24 views
  • 24 Jan, 2021
  • 1 location
Nebulized Sub-dissociative Dose Ketamine at Three Different Dosing Regimens for Treating Acute Pain in the Pediatric ED

In the situation when intravenous access is not readily available or unobtainable, sub-dissociative dose ketamine can be administered via intranasal route (IN). The data supporting intranasal route in pediatric patients is somewhat conflicting with regards to the optimum intranasal dose (range 0.75-1 mg/kg) and frequencies of administration. Hence, another non-invasive …

acute pain
ketamine
postoperative pain
analgesics
analgesia
  • 4 views
  • 27 Mar, 2021
  • 1 location
Endourology Disease Group Excellence (EDGE) Consortium: Antibiotics (Abx) for Percutaneous Nephrolithotomy (PCNL) Part 2

This study will be a multi-institutional randomized clinical trial of a short course of pre-operative antibiotic prophylaxis in addition to perioperative antibiotics prior to undergoing percutaneous nephrolithotomy. The select patient population will be those patients deemed to be at a moderately increased risk of postoperative infectious complications. These higher risk …

antibiotics
antibiotic therapy
percutaneous nephrolithotomy
ampicillin
nitrofurantoin
  • 35 views
  • 24 Jan, 2021
  • 1 location
Computer-assisted Oxygen Therapy Weaning in Critically Ill Children

The study is designed to evaluate the feasibility, safety and clinical utility of using an adaptive model to wean oxygen by computer assistance. Investigators hypothesize that weaning oxygen using this model will decrease duration of exposure to hyperoxia, decrease duration of exposure to hypoxia, decrease exposure to increased oxygen requirement, …

FIO2
  • 1 views
  • 10 Apr, 2021
  • 1 location