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Found 32 clinical trials
Remote Ischemic Conditioning in Patients With Acute Stroke (RESIST) (RESIST)

Our primary aim is to investigate whether remote ischemic conditioning (RIC) as an adjunctive treatment can improve long-term recovery in acute stroke patients as an adjunct to standard treatment.

ischemia
acute stroke
stroke
limb ischemia
adjunctive treatment
  • 16 views
  • 26 Mar, 2022
  • 4 locations
24 Hours Treatment With Alteplase in Patients With Ischemic Stroke

The development of intravenous thrombolysis has greatly improved the rate of recanalization and reperfusion in patients with acute ischemic stroke, increasing the proportion of patients with good outcome and reduced mortality. The guideline recommends that patients with ischemic stroke should be treated with intravenous thrombolysis within 4.5 hours. The latest …

  • 0 views
  • 24 Jul, 2021
  • 1 location
The Norwegian Tenecteplase Stroke Trial 2 (NOR-TEST 2)

Background: Alteplase is the only approved acute drug treatment in ischemic stroke and aims at dissolving arterial clots causing cerebral ischemia. The overall benefit of alteplase is

infarct
ischemic stroke
tissue plasminogen activator
ischemia
thrombolytic
  • 107 views
  • 23 May, 2022
  • 1 location
Optimal Coronary Flow After PCI for Myocardial Infarction - a Pilot Study (OPTIMAL)

In this study the investigators test the hypothesis that alteplase given intra coronary after PCI reduce infarct size in patients with ST-elevation myocardial infarction(STEMI) and impaired

alteplase
stemi
angiography
tissue plasminogen activator
  • 0 views
  • 24 Feb, 2022
  • 1 location
Early Antiplatelet Therapy After Hemorrhagic Infarction in Acute Ischemic Stroke Treated With Intravenous Thrombolysis (HITs)

Previous study showed that the proportions of hemorrhagic Infarction after intravenous thrombolysis were 24.2% and 32.5% in the control group and the alteplase group, and most of them were

  • 0 views
  • 11 May, 2022
  • 1 location
Low Dose Catheter Directed Thrombolysis for Acute Pulmonary Embolism (BETULA)

(APTT) is 2-2.5 of reference value) or CDT (4mg alteplase (r-tPA) per catheter, infusion over 2 hours) in an open label, outcome assessor blinded, randomized, controlled trial. Primary efficacy endpoint

computed tomography angiography
acute pulmonary embolism
clot
heparin
alteplase
  • 1 views
  • 01 Mar, 2022
  • 1 location
Inhaled Recombinant Non-immunogenic Staphylokinase vs Placebo in Patients With COVID-19 - FORRIF Trial (FORRIF)

Objective: to evaluate the tolerability, safety and efficacy of inhaled usage of the Recombinant Non-immunogenic Staphylokinase (Fortelyzin®) vs placebo in patients with COVID-19.

  • 0 views
  • 22 Mar, 2022
  • 1 location
Endovascular Acute Stroke Intervention - Tandem OCclusion Trial

Patients with tandem occlusion or tandem lesion (TL), that is, stroke with an acute intracranial anterior circulation occlusion and an ipsilateral cervical ICA (c-ICA) high-grade stenosis or occlusion, constitute about 15-20% of patients undergoing endovascular thrombectomy (EVT). However, the optimal treatment of acute stroke patients with TL remains uncertain, as …

stenosis
balloon angioplasty
heparin
clopidogrel
probe
  • 1 views
  • 13 Aug, 2021
  • 1 location
Thrombus Composition in Ischemic Stroke: Analysis of the Correlation With Plasma Biomarkers, Efficacy of Treatment, Etiology and Prognosis (COMPO-CLOT)

The recent validation of thrombectomy in addition to thrombolysis with intravenous administration of alteplase suggests a major revolution in the management of acute strokes. This treatment

ischemic stroke
tissue plasminogen activator
cerebral infarction
plasminogen activator
acute stroke
  • 0 views
  • 17 Sep, 2022
  • 6 locations
Biomarkers algOrithm for strOke diagnoSis and Treatment Resistance Prediction

occlusion (LVO) is the association of intravenous (IV) alteplase administration and mechanical thrombectomy (MT). However, there are limited places where MT can be performed. Therefore, there is a need for

  • 0 views
  • 02 Jul, 2021
  • 4 locations