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Found 33 clinical trials
Improving Neuroprotective Strategy for Ischemic Stroke With Poor Recanalization After Thrombectomy by Intra-arterial TNK (INSIST-TNK)

reperfusion and better functional outcome than alteplase among patients with ischemic stroke treated within 4.5 hours after symptom onset. This study intends to explore the proportion of sufficient

plasminogen
thrombectomy
alteplase
stroke
  • 0 views
  • 09 Jun, 2022
  • 1 location
Platelet Function in Patients With Ischemic Stroke Treated With Anti-thrombotic or Thrombolytic

Acute stroke afflicts nearly 700,000 patients in the US and is the number 3 cause of death. Only 2-9% of this large number is treated with t-PA if they arrive within 4.5 hours. An equally small percentage of patients with large vessel occlusion undergo thrombectomy. The thrombectomy patients may or …

  • 0 views
  • 04 Jul, 2022
  • 1 location
Mesenchymal Stem Cells for The Treatment of Acute Ischemic Stroke

The clinical study with UMC119-06 is designed to investigate the safety in patients with acute ischemic stroke ("AIS"). This will be a dose escalation, open-label, single-center study in adult with acute ischemic stroke. UMC119-06 is ex vivo cultured human umbilical cord tissue-derived mensenchymal stem cells product which is intended for …

  • 1 views
  • 02 Mar, 2022
  • 1 location
Bloodletting Puncture in the Treatment of Acute Ischemic Stroke

The bloodletting puncture is an external treatment for acute ischemic stroke by releasing an appropriate amount of blood with a three-edged needle at specific points on the patient's body. As a special treatment for acute ischemic stroke, it has been used clinically in hospitals of traditional Chinese medicine in China …

  • 0 views
  • 06 May, 2022
  • 1 location
A Study in Chinese Patients to Compare How Tenecteplase and Alteplase Given After a Stroke Improve Recovering of Physical Activity

alteplase within 4 hours and 30 minutes after stroke. The purpose of this study is to compare how tenecteplase and alteplase improve peoples' recovering of physical activity. Alteplase is standard of care

  • 0 views
  • 25 Jul, 2022
  • 51 locations
Tenecteplase in Wake-up Ischaemic Stroke Trial (TWIST)

Stroke is a leading causes of death and disability. At least 20% of strokes occur during sleep, so- called 'wake up stroke'. Thrombolysis with the clot-busting drug alteplase is effective for

plasminogen activator
wake up
plasminogen
alteplase
ischemic stroke
  • 202 views
  • 31 Jan, 2022
  • 70 locations
  • 1 views
  • 29 Apr, 2022
  • 66 locations
CLiCK in the Critical Care Unit (CLiCK)

occlusion, and alteplase use in the ICU of six ICU's compared to the standard of care saline lock.

  • 0 views
  • 29 Jul, 2022
  • 1 location
Intravenous rhTNK-tPA Bridging With Endovascular Treatment Versus Endovascular Treatment Alone For Stroke Patient With Large Vessel Occlusion: A Multicenter, Randomized Controlled Trial (BRIDGE-TNK)

The purpose of this trial is to investigate whether intravenous rhTNK-tPA prior to endovascular treatment can improve 90-day functional outcome of stroke patients with large vessel occlusion who are thrombolysis-eligible within 4.5 hours of symptom onset.

  • 0 views
  • 17 Sep, 2022
  • 3 locations
Efficacy and Safety of CUSA-081 in the Restoration of Central Venous Access Device (CVAD) Functionality (READY 1)

Study to evaluate the efficacy and safety of CUSA-081 in the restoration of central venous access device (CVAD) functionality in participants 18 years and older.

tissue plasminogen activator
alteplase
  • 27 views
  • 24 Apr, 2022
  • 63 locations