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Found 29 clinical trials
TheraSphere & Treatment of Unresectable Primary or Unresectable Secondary Liver Cancer

Protocol Synopsis Title A Humanitarian Device Exemption Use Protocol of TheraSphere For Treatment of Unresectable Primary or Secondary Liver Neoplasia Supplier BTG International Canada Inc. Type of Clinical Use Post-Marketing: TheraSphere commercially distributed under HDE # 980006 Objectives Provide supervised access to TheraSphere therapy at this institution Evaluate response to …

  • 0 views
  • 23 Jan, 2021
  • 1 location
Serum Alpha-fetoprotein Levels and Response to Direct Antiviral Therapy in Patients With Chronic Hepatitis C

Alpha-fetoprotein Levels on the Response to direct Antiviral Therapy in Patients with Chronic Hepatitis C

sofosbuvir
chronic hepatitis
alpha fetoprotein
antiviral drugs
ledipasvir/sofosbuvir
  • 8 views
  • 22 Jan, 2021
  • 1 location
Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery

This partially randomized phase II/III trial studies how well, in combination with surgery, cisplatin and combination chemotherapy works in treating children and young adults with hepatoblastoma or hepatocellular carcinoma. Drugs used in chemotherapy, such as cisplatin, doxorubicin, fluorouracil, vincristine sulfate, carboplatin, etoposide, irinotecan, sorafenib, gemcitabine and oxaliplatin, work in different …

cancer
abdominal compartment syndrome
vincristine
carboplatin
fluorouracil
  • 178 views
  • 13 Jun, 2021
  • 137 locations
AFP T in Advanced HCC

expressing tumor. Those who did not tolerate or refused other therapies may also participate. The purpose of this study is to test the safety of genetically changed T cells that target alpha-fetoprotein (AFP

cholangiocarcinoma
alpha fetoprotein
tumor cells
measurable disease
  • 17 views
  • 12 Jun, 2021
  • 19 locations
Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors

This randomized phase III trial studies how well standard-dose combination chemotherapy works compared to high-dose combination chemotherapy and stem cell transplant in treating patients with germ cell tumors that have returned after a period of improvement or did not respond to treatment. Drugs used in chemotherapy, such as paclitaxel, ifosfamide, …

cancer
stem cell transplantation
human chorionic gonadotropin
testicular
alpha fetoprotein
  • 803 views
  • 13 Jun, 2021
  • 94 locations
Active Surveillance Bleomycin Carboplatin Etoposide or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

This phase III trial studies how well active surveillance, bleomycin, carboplatin, etoposide, or cisplatin work in treating pediatric and adult patients with germ cell tumors. Active surveillance may help doctors to monitor subjects with low risk germ cell tumors after their tumor is removed. Drugs used in chemotherapy, such as …

cancer
human chorionic gonadotropin
beta-human chorionic gonadotropin
neutrophil count
bleomycin
  • 341 views
  • 03 Jun, 2021
  • 369 locations
PD-1 Antibody + XELOX in 1st Line Serum A-fetoprotein (AFP)-Elevated Gastric or Gastroesophageal Junction Adenocarcinoma

The purpose of this study is to evaluate the efficacy and safety of of anti-PD-1 antibody in combination with chemotherapy as first-line treatment in patients with unresectable, locally advanced recurrent or metastatic serum AFP-elevated gastric and gastroesophageal junction adenocarcinoma.

  • 2 views
  • 25 Apr, 2021
  • 1 location
PD-1 Antibody + Apatinib Mesylate in 2+ Line Serum AFP-elevated Gastric Adenocarcinoma

The purpose of this study is to evaluate the efficacy and safety of PD-1 antibody combined with apatinib mesylate in patients with unresectable, local advanced recurrent or metastatic serum AFP-elevated gastric adenocarcinoma, who have at least received first-line antitumor therapy or whose standard treatment is intolerable.

  • 0 views
  • 23 Apr, 2021
  • 1 location
Study of Camrelizumab (SHR-1210) and Apatinb Based Therapies for Alpha-fetoprotein (AFP)-Producing Gastric Cancer or Gastroesophageal Junction Adenocarcinoma

This is a study of Camrelizumab (SHR-1210) and Apatinb for unresectable Recurrent or metastatic alpha-fetoprotein (AFP)-producing gastric cancer or Gastroesophageal Junction Adenocarcinoma

immunostimulants
adenocarcinoma
adjuvant therapy
neutrophil count
oxaliplatin
  • 0 views
  • 26 Jan, 2021
  • 1 location
Study of ET140203 T Cells in Adults With Advanced Hepatocellular Carcinoma (ARYA-1)

Open-label, dose escalation, multi-center, Phase I / II study to assess the safety of an autologous T-cell product (ET140203) in adult subjects with Alpha-fetoprotein (AFP)-positive/Human

hepatocellular carcinoma
alpha fetoprotein
measurable disease
line of therapy
carcinoma
  • 30 views
  • 04 Jun, 2021
  • 4 locations