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Found 90 clinical trials
A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects With VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) Syndrome

Background Allogeneic hematopoietic stem cell transplant involves taking blood stem cells from a donor and giving them to a recipient. The transplants are used to

busulfan
allogeneic hematopoietic stem cell transplant
mycophenolate mofetil
fludarabine
total body irradiation
  • 0 views
  • 16 Sep, 2022
  • 1 location
A Study of Blinatumomab in Patients With Pre B-cell ALL and B-cell NHL as Post-allo-HSCT Remission Maintenance

The investigators primary objective is to determine the safety and toxicity of incorporating blinatumomab into the post-allogeneic hematopoietic stem cell transplant (HSCT) maintenance setting

flow cytometry
cancer
mycophenolate mofetil
b-cell acute lymphoblastic leukemia
leukemia
  • 4 views
  • 08 Jun, 2022
  • 1 location
TCR +/CD19+ Depleted Allogeneic Hematopoietic Stem Cell Transplantation for Malignant and Non-malignant Disorders

The purpose of this study is to investigate the safety and efficacy of TCR+/CD19+ depleted allogeneic hematopoietic stem cell transplant (HSCT) for malignant and non-malignant disorders in

  • 0 views
  • 30 Sep, 2021
  • 1 location
Study of Intensity Modulated Total Marrow Irradiation (IM-TMI) in Addition to Fludarabine/Busulfan Conditioning for Allogeneic Transplantation in High Risk AML and Myelodysplastic Syndromes

(FluBu) conditioning prior to allogeneic hematopoietic stem cell transplant (HSCT).

blast cells
refractory acute myeloid leukemia (aml)
cytopenia
fludarabine
hla-a
  • 6 views
  • 30 Jun, 2022
  • 1 location
ONC 201 Maintenance Therapy in Acute Myeloid Leukemia and Myelodysplastic Syndrome After Stem Cell Transplant

This is a single-center pilot study of 20 patients with AML/MDS. Eligible patients will be enrolled following an informed consent between 6-20 weeks after allogeneic hematopoietic stem cell

myeloid leukemia
blast cells
residual tumor
leukemia
minimal residual disease
  • 18 views
  • 04 Oct, 2022
  • 1 location
Myeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders

This is a Phase II study of allogeneic hematopoietic stem cell transplant (HCT) using a myeloablative preparative regimen (of either total body irradiation (TBI); or, fludarabine/busulfan for

myelomonocytic leukemia
chronic lymphocytic leukemia
leukemia
b-cell small lymphocytic lymphoma
burkitt's lymphoma
  • 58 views
  • 06 May, 2022
  • 1 location
Cemiplimab in AlloSCT/SOT Recipients With CSCC

In this research study, Cemiplimab is being evaluated as a treatment for advanced cutaneous squamous cell carcinoma in participants who have previously received an allogeneic hematopoietic stem

squamous cell carcinoma
carcinoma
serum follicle stimulating hormone
sirolimus
prednisone
  • 0 views
  • 04 Oct, 2022
Human Lysozyme Goat Milk for the Prevention of Graft Versus Host Disease in Patients With Blood Cancer Undergoing a Donor Stem Cell Transplant

This phase I trial studies the side effects of human lysozyme goat milk in preventing graft versus host disease in patients with blood cancer undergoing a donor stem cell transplant. Sometimes the transplanted cells from a donor can cause an immune response against the body's own normal cells (call graft …

cancer
cell transplantation
total body irradiation
cyclophosphamide
karnofsky performance status
  • 0 views
  • 04 Oct, 2022
  • 1 location
BMT-08: A Comparative Effectiveness Study of Transdermal Granisetron to Ondansetron

Patients undergoing either an autologous or allogeneic hematopoietic stem cell transplant (HSCT) and receiving preparative chemotherapy experience a considerable amount of chemotherapy-induced

antiemetics
dexamethasone
quetiapine
granisetron
ondansetron
  • 1 views
  • 16 Jun, 2022
  • 1 location
Hematopoietic Stem Cell Transplant for Dyskeratosis Congenita or Severe Aplastic Anemia

Fludarabine-based preparative regimen followed by an allogeneic hematopoietic stem cell transplant using related or unrelated donor in persons 0-70 years of age diagnosed with dyskeratosis

pancytopenia
cytopenia
fludarabine
cyclophosphamide
platelet transfusion
  • 24 views
  • 24 Mar, 2022
  • 1 location