Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 45 clinical trials
Immunotherapy in Peripheral T Cell Lymphoma - the Role of Alemtuzumab in Addition to Dose Dense CHOP

antibody alemtuzumab in primary and relapsed T cell lymphoma. The investigators thus propose to investigate the value of adjuvant alemtuzumab in combination with dose dense CHOP-14 in patients

b-cell lymphoma
peripheral t-cell lymphoma
lymphoma
measurable disease
t-cell lymphoma
  • 10 views
  • 07 Nov, 2020
  • 1 location
Alemtuzumab and Low-Dose Cyclosporine in Treating Patients With Severe Aplastic Anemia or Acquired Marrow Failure

RATIONALE: Immunosuppressive therapies, such as alemtuzumab and cyclosporine, may improve bone marrow function and increase blood cell counts. Giving alemtuzumab together with

anemia
bone marrow procedure
immunosuppressive agents
  • 44 views
  • 07 Nov, 2020
  • 1 location
Alemtuzumab and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II Stage III or Stage IV T-Cell Non-Hodgkin's Lymphoma

RATIONALE: Monoclonal antibodies, such as alemtuzumab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and

prednisone
hodgkin's disease
combination chemotherapy
vincristine
monoclonal antibodies
  • 46 views
  • 07 Nov, 2020
  • 3 locations
Stem Cell Transplant in Patients With Severe Sickle Cell Disease

-myeloablative conditioning regimen (Alemtuzumab).

priapism
iron
acute chest syndrome
blood transfusion
cell transplantation
  • 30 views
  • 02 Apr, 2021
  • 1 location
Minimizing Toxicity in HLA-identical Related Donor Transplantation for Children With Sickle Cell Disease

This multisite prospective study seeks to determine if HLA-identical sibling donor transplantation using alemtuzumab, low dose total-body irradiation, and sirolimus (Sickle transplant Using a

thalassemia
transcranial doppler ultrasonography
priapism
blood transfusion
acute chest syndrome
  • 21 views
  • 24 Jan, 2021
  • 6 locations
Nonmyeloablative Stem Cell Transplant in Children With Sickle Cell Disease and a Major ABO-Incompatible Matched Sibling Donor

sickle cell disease (SCD) who have a matched related major ABO-incompatible donor. The nonmyeloablative regimen will use alemtuzumab, total body irradiation (TBI) and sirolimus for immune suppression

total body irradiation
splenic sequestration crisis
priapism
hb s
blood transfusion
  • 9 views
  • 24 Jan, 2021
  • 1 location
Islet Cell Transplant for Type 1 Diabetes

produce insulin, which can improve blood sugar control and eliminate the need to inject insulin or use an insulin pump. Anti-thymocyte globulin (ATG) and alemtuzumab (Campath) are anti-rejection

hemoglobin a1c
pancreatic islet transplantation
immunosuppression
diabetic ketoacidosis
immunosuppressive agents
  • 793 views
  • 27 Jan, 2021
  • 1 location
Nonmyeloablative Conditioning for Mismatched Hematopoietic Stem Cell Transplantation for Severe Sickle Cell Disease

with severe sickle cell disease (SCD) who undergo a non-myeloablative preparative regimen consisting of total body irradiation (TBI), cyclophosphamide and alemtuzumab (and fludarabine for haplo-SCT

priapism
acute chest syndrome
blood transfusion
cell transplantation
stroke
  • 14 views
  • 24 Apr, 2021
  • 1 location
PolyTreg Immunotherapy in Islet Transplantation

is to assess the effect of Tregs on beta cell function in islet transplant patients. The control group (6) will receive the current Edmonton islet transplant induction therapy (Alemtuzumab

hemoglobin a1c
plasma glucose
pancreatic islet transplantation
fasting
immunosuppression
  • 364 views
  • 23 Jan, 2021
  • 1 location
SCT Plus Immune Therapy in Average Risk AML/MDS

Allogeneic stem cell transplantation followed by targeted immune therapy with Gemtuzumab Ozogamicin (Mylotarg) will be given to patients with average risk AML or MDS.

aml/mds
gemtuzumab ozogamicin
gemtuzumab
bone marrow procedure
cell transplantation
  • 22 views
  • 25 Jan, 2021
  • 1 location