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Found 24 clinical trials
Site and Mechanism(s) of Expiratory Airflow Limitation in COPD Emphysema and Asthma-COPD Overlap

The purpose of this cross-sectional, observational study is to evaluate the site and mechanism(s) for expiratory airflow limitation in chronic, treated, current or former smokers (>15 pack years) with COPD, Emphysema, and Asthma-COPD Overlap with mild to severe expiratory airflow limitation. Treatment may include short and long acting inhaled beta2agonists, …

corticosteroids
bronchiectasis
antibiotics
bronchitis
COPD
  • 54 views
  • 19 Feb, 2021
  • 1 location
Dysbiosis Impact on Lung Disease in HIV

Despite the high burden of respiratory symptoms in the HIV+ population, causes of chronic obstructive pulmonary disease (COPD) in individuals with HIV are poorly understood. Microbial communities present in the lungs or gut could play an important role in COPD via their ability to stimulate inflammation and oxidative stress and …

HIV Vaccine
bronchoscopy
pulmonary function test
respiratory symptom
hiv-1 infection
  • 0 views
  • 16 Sep, 2021
  • 1 location
ProAir Digihaler in COPD Disease Management: A Real World Study

A pilot study to explore the utilization of the TEVA ProAir Digihaler rescue medication use and inhalation parameters to identify disease deterioration to help in the management of COPD patients in clinical practice. The study is designed to follow a small sample size of patients with COPD, monitor and collect …

  • 0 views
  • 22 May, 2021
  • 1 location
Efficacy of Mepolizumab in Severe Asthmatics (MESILICO)

Interleukin (IL)-5 is the main cytokine responsible for the activation of eosinophils, hence therapeutic strategies have been investigated and developed for clinical use. Biologics targeting IL-5 and its receptor (first mepolizumab and subsequently, reslizumab and benralizumab), have been recently approved and used as add-on therapy for severe eosinophilic asthma resulting …

  • 0 views
  • 30 Jan, 2021
  • 1 location