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Found 26 clinical trials
Propranolol Hydrochloride and Pembrolizumab for the Treatment of Recurrent or Metastatic Urothelial Cancer

This phase II trial studies the effect of propranolol hydrochloride and pembrolizumab in treating patients with urothelial cancer that has come back (recurrent) or has spread to other places in the body (metastatic). Propranolol hydrochloride is used for the treatment of chronic angina, cardiac arrhythmias, essential tremor, hypertension, and as …

  • 0 views
  • 31 May, 2021
  • 1 location
Olaparib in Treating Patients With Metastatic or Advanced Urothelial Cancer With DNA-Repair Defects

This phase II trial studies how well olaparib works in treating patients with urothelial cancer with deoxyribonucleic acid (DNA)-repair defects that has spread to other places in the body (advanced or metastatic) and usually cannot be cured or controlled with treatment. PARPs are proteins that help repair DNA mutations. PARP …

avelumab
cancer
bladder cancer
follicle stimulating hormone
pembrolizumab
  • 92 views
  • 26 Jul, 2021
  • 4 locations
Sonidegib and Pembrolizumab in Treating Patients With Advanced Solid Tumors

This phase I trial studies the best dose of sonidegib when given together with pembrolizumab and to see how well they work in treating patients with solid tumor that has spread to other places in the body (advanced). Sonidegib may stop the growth of tumor cells by blocking some of …

cancer
pembrolizumab
systemic therapy
monoclonal antibodies
stage iv non-small cell lung cancer
  • 0 views
  • 30 Jan, 2021
  • 4 locations
Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV

This phase I trial investigates the side effects of cabozantinib and nivolumab in treating patients with cancer that has spread to other places in the body (advanced) and who are undergoing treatment for human immunodeficiency virus (HIV). Cabozantinib may stop the growth of tumor cells by blocking some of the …

antiretroviral therapy
cancer
enzyme-linked immunosorbent assay
hepatitis
hiv test
  • 0 views
  • 25 Jul, 2021
  • 2 locations
Testing the Addition of an Anti-cancer Drug BAY 1895344 to the Usual Chemotherapy Treatment (Cisplatin or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer

This phase I trial identifies the best dose, possible benefits and/or side effects of BAY 1895344 in combination with chemotherapy in treating patients with solid tumors or urothelial cancer that has spread to other places in the body (advanced). BAY 1895344 may stop the growth of tumor cells by blocking …

  • 0 views
  • 10 Jul, 2021
  • 1 location
Prospective Study of Adjuvant Radiotherapy in High Risk Bladder Cancer.

This prospective interventional study aims at evaluating the safety and efficacy of an adjuvant radiation treatment in cases of muscle-invasive bladder cancer, submitted to radical cystectomy and presenting clinic-pathological characteristics of high risk of recurrence.

cancer
invasive bladder cancer
bladder cancer
bladder tumor
metastasis
  • 10 views
  • 26 Jan, 2021
  • 1 location