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Found 26 clinical trials
Avelumab in Combination With AVB-S6-500 in Patients With Advanced Urothelial Carcinoma

The purpose of this research study is to test the safety of avelumab and AVB-S6-500 and see what effects (good and bad) this combination treatment has on patients with advanced urothelial

carboplatin
measurable disease
avelumab
metastatic urothelial carcinoma
advanced urothelial carcinoma
  • 5 views
  • 14 Jun, 2021
  • 4 locations
TALazoparib and Avelumab as Maintenance Therapy in Platinum-Sensitive Metastatic or Locally Advanced URothelial Carcinoma

The main objectif is to determine the efficacy of a maintenance treatment combining Talazoparib and Avelumab after platinum-based chemotherapy in patients with locally advanced/metastatic urothelial carcinoma.

neutrophil count
platinum-based chemotherapy
carboplatin
platelet count
avelumab
  • 0 views
  • 19 Jun, 2021
  • 1 location
Radio-Immunotherapy Before Cystectomy in Locally Advanced Urothelial Carcinoma of the Bladder

urothelial carcinoma of the bladder

radical cystectomy
bladder carcinoma
gilbert's syndrome
carcinoma
metastasis
  • 5 views
  • 24 Jan, 2021
  • 8 locations
Neoadjuvant Dose Dense MVAC in MIBC and Locally Advanced Urothelial Carcinoma

The objective is to investigate the efficacy and safety of four cycles of ddMVAC with G-CSF support in patients with MIBC and locally advanced UC

g-csf
bladder cancer
vinblastine
metastasis
renal function
  • 1 views
  • 24 Jan, 2021
  • 1 location
A Study of Anti-PD-L1 Antibody ZKAB001 Combined With Albumin-bound Paclitaxel in Advanced Urothelial Carcinoma

To evaluate the safety and efficacy of recombinant anti-PD-L1 monoclonal antibody injection (ZKAB001) combined with Albumin-bound paclitaxel in the treatment of Advanced urothelial carcinoma

  • 0 views
  • 22 May, 2021
  • 1 location
Selinexor and Pembrolizumab for the Treatment of Cisplatin-Ineligible or Cisplatin-Refractory Locally Advanced or Metastatic Urothelial Carcinoma

This phase Ib/II trial finds the best dose of selinexor and its effect with pembrolizumab in treating patients with urothelial carcinoma that are not eligible to receive the chemotherapy drug cisplatin, or have been given cisplatin and the cancer has gotten worse. Patients must also have urothelial carcinoma that has …

  • 0 views
  • 29 Apr, 2021
  • 1 location
Four Cycles Versus Six Cycles of Cisplatin-based Chemotherapy in Metastatic Urothelial Carcinoma

patients with advanced urothelial carcinoma.

g-csf
doxorubicin
metastatic urothelial carcinoma
carcinoma
gemcitabine
  • 58 views
  • 21 Jan, 2021
  • 19 locations
Safety Tolerability and Pharmacokinetics of TWP-101 in Patients With Advanced Melanoma and Urothelial Carcinoma

This study is a multi-center, phase Ia/Ib, open clinical study to evaluate the safety, tolerability and pharmacokinetics of TWP-101 in patients with advanced melanoma and urothelial carcinoma. This study consists of two parts (Part A and Part B). Part A was a dose escalation study, and Part B was a …

  • 0 views
  • 25 Jul, 2021
  • 1 location
Tazemetostat and Pembrolizumab in Treating Patients With Locally Advanced or Metastatic Urothelial Carcinoma

This phase I/II trial studies the side effects and best dose of tazemetostat and how well it works when given together with pembrolizumab in treating patients with urothelial carcinoma that has spread to nearby tissue or lymph nodes or other places in the body (locally advanced/metastatic). Tazemetostat may stop the …

  • 36 views
  • 18 Jul, 2021
  • 26 locations
Adjuvant Versus Progression-Triggered Gemcitabine Monotherapy for Locally Advanced Bladder Cancer

Primary Objective: - To analyse time to tumor progression in patients cystectomized for locally advanced transitional cell carcinoma (TCC) of the bladder, who are not suitable

bladder cancer
radical cystectomy
transitional cell carcinoma of the bladder
squamous cell carcinoma
bladder carcinoma
  • 39 views
  • 07 Nov, 2020
  • 1 location