Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 50 clinical trials
A Two-arm (Phase 2) Exploratory Study of Nivolumab Monotherapy or in Combination With Nab-paclitaxel and Carboplatin in Early Stage NSCLC in China

other countries for the treatment of patients with unresectable or metastatic melanoma, advanced NSCLC with progression on or after platinum-based chemotherapy, advanced RCC whose disease progressed on

paclitaxel
carboplatin
squamous cell carcinoma
cancer chemotherapy
carcinoma
  • 0 views
  • 23 Jan, 2021
Cabozantinib S-malate and Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Genitourinary Tumors

This phase I trial studies the side effects and best doses of cabozantinib s-malate and nivolumab with or without ipilimumab in treating patients with genitourinary (genital and urinary organ) tumors that have spread to other places in the body (metastatic). Cabozantinib s-malate may stop the growth of tumor cells by …

kidney cancer
tyrosine
tumor cells
carcinoma
oophorectomy
  • 128 views
  • 03 Feb, 2021
  • 2 locations
Pembrolizumab With or Without Axitinib for Treatment of Locally Advanced or Metastatic Clear Cell Kidney Cancer in Patients Undergoing Surgery

This phase II trial studies how well pembrolizumab with or without standard of care axitinib works in treating patients with clear cell kidney cancer that has spread to nearby tissues or lymph nodes (locally advanced) or other places in the body (metastatic) who are undergoing surgery. Pembrolizumab is an antibody …

  • 0 views
  • 27 Jan, 2021
  • 1 location
SLM + Axitinib for Clear Cell RCC

This is a Phase I/II trial for safety and preliminary efficacy of the combination of axitinib and selenomethionine (SLM) for adult patients with advanced metastatic clear cell renal cell carcinoma (CCRCC). This will be a two part study consisting of a dose escalation and expansion study. In addition, a pilot …

  • 25 views
  • 26 Jan, 2021
  • 1 location
Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV

This phase I trial investigates the side effects of cabozantinib and nivolumab in treating patients with cancer that has spread to other places in the body (advanced) and who are undergoing treatment for human immunodeficiency virus (HIV). Cabozantinib may stop the growth of tumor cells by blocking some of the …

  • 0 views
  • 13 Feb, 2021
  • 1 location
Neoadjuvant AXITINIB and AVELUMAB for Patients With Localized Clear-cell RCC

a monocenter, open label, single arm, phase II study of the combination of axitinib with avelumab as neoadjuvant therapy in patients with intermediate to high-risk non-metastatic RCC.

renal function tests
carcinoma
axitinib
serum pregnancy test
  • 7 views
  • 22 Jan, 2021
  • 1 location
Evaluating the Safety and Efficacy of Pembrolizumab Combined With MWA for Advanced NSCLC

This is a prospective, randomized, single clinical study designed to evaluate its safety and efficacy by using Microwave Ablation combine with Pembrolizumab in patients with Stage BNon -small Cell Lung.Cancer (NSCLC) who failed with first-line therapy.

metastasis
secondary malignant neoplasm of liver
lung carcinoma
pembrolizumab
cancer treatment
  • 1 views
  • 25 Jan, 2021
  • 1 location
A Phase II Study of Bevacizumab and Erlotinib in Subjects With Advanced Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) or Sporadic Papillary Renal Cell Cancer

Background At the present time, there are no drugs that have been proven to work in patients with papillary kidney cancer that has spread (metastasized) beyond the kidneys. Researchers are interested in determining whether the combination of the drugs bevacizumab and erlotinib can be used to treat metastatic papillary kidney …

  • 23 views
  • 03 Mar, 2021
  • 1 location
NeoVax With Nivolumab in Patients With Ovarian Cancer

This research study is evaluating a new type of vaccine called "Personalized NeoAntigen Cancer Vaccine" in combination with Nivolumab (Opdivo) for ovarian cancer.

ovarian epithelial carcinoma
angiogenesis inhibitor
cancer chemotherapy
peritoneal cancer
platelet count
  • 0 views
  • 27 Jan, 2021
Mechanism of Sorafenib Resistance in Patients With Advanced Hepatocellular Carcinoma

It has been shown previously that gene expression profiling signature (a set of dysregulated genes) can be used for molecular classification, diagnosis, and prognosis of several types of cancers. In This study the hypothesise that resistant tumor may be due to genetic mutations and/or other alternative pathways that could be …

sorafenib
cancer
vascular invasion
international normalized ratio
coumadin
  • 16 views
  • 23 Jan, 2021
  • 1 location