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Found 94 clinical trials
  • 0 views
  • 15 May, 2022
  • 1 location
A Phase 2, Multicenter, Open-Label Study of SCIB1 in Patients With Advanced Unresectable Melanoma Receiving Pembrolizumab

, and also if SCIB1 can help to make those responses last longer. Pembrolizumab is considered a standard treatment for patients with advanced melanoma. SCIB1 is considered experimental. SCIB1 has been

immunologic adjuvant
pembrolizumab
unresectable melanoma
metastatic melanoma
ct scan
  • 21 views
  • 05 Mar, 2022
  • 4 locations
A Study to Assess Safety and Efficacy of Relatlimab With Ipilimumab in Participants With Advanced Melanoma Who Progressed on Anti-Programmed Cell Death Protein 1 (Anti-PD-1) Treatment

The primary purpose of this study is to characterize the safety, tolerability, and dose-limiting toxicities (DLTs) and to determine the recommended dose of relatlimab in combination with ipilimumab (for dose escalation). It is also to evaluate the safety, tolerability, and preliminary efficacy of the recommended dose of relatlimab in combination …

advanced melanoma
nivolumab
ipilimumab
pembrolizumab
BRAF
  • 3 views
  • 27 May, 2022
  • 8 locations
Whole-body DW-MRI and cfDNA Analysis for the Surveillance of Melanoma Patients at High Risk for Recurrence.

Patients with locally advanced melanoma are at high risk for recurrence following surgical treatment. More patients with stage IV melanoma remain in complete remission following systemic therapy

advanced melanoma
systemic therapy
metastatic melanoma
  • 8 views
  • 26 Jan, 2021
  • 3 locations
A Study of Pembrolizumab With Carboplatin and Gemcitabine in Patients With Metastatic Triple Negative Breast Cancer

negative breast cancer. Pembrolizumab is a drug which may help the immune system to target and destroy cancer cells. Pembrolizumab has been approved by the FDA for the treatment of advanced melanoma

measurable disease
metastasis
breast cancer
triple negative breast cancer
ct scan
  • 417 views
  • 23 Feb, 2022
  • 6 locations
Neoadj Admin Autologous Tumor Infiltrating Lymphocytes & Pembrolizumab for Treatment of Adv Melanoma Patients

This phase I/II trial tests the safety and side effects of lifileucel and pembrolizumab in treating patients with stage IIIB-D melanoma that has spread to nearby tissue or lymph nodes (locally advanced). Biological therapies, such as lifileucel, use substances made from living organisms that may attack specific tumor cells and …

  • 0 views
  • 15 May, 2022
  • 1 location
Nodal Radiation Therapy for Sentinel Lymph Node Positive Melanoma

planned for immunotherapy without completion lymph node dissection. Prior studies of patients with more advanced melanoma have shown nodal radiation therapy can decrease the risk of nodal recurrence but

advanced melanoma
metastasis
nivolumab
pembrolizumab
  • 0 views
  • 01 Oct, 2021
SpotCheck: Comparison of Enhanced Telemedicine Versus In-person Evaluation for the Diagnosis of Skin Cancer

advanced melanomas (with a concomitant increase in the diagnosis of earlier stage tumors), and potentially decrease melanoma mortality.

skin lesion
cancer
Accepts healthy volunteers
  • 0 views
  • 30 May, 2022
  • 1 location
Phase II Trial of Combination Anti-PD-1 and Aldesleukin for Metastatic Melanoma and Renal Cell Carcinoma

Background Aldesleukin is used to treat metastatic or advanced melanoma and renal cell carcinoma. Pembrolizumab is used to treat many cancers including melanoma

  • 0 views
  • 01 Jul, 2022
  • 1 location
A Phase II Study of the Interleukin-6 Receptor Inhibitor Tocilizumab in Combination With Ipilimumab and Nivolumab in Patients With Unresectable Stage III or Stage IV Melanoma

doses in combination with ipilimumab and nivolumab for four induction doses to week 12, then maintenance nivolumab alone up to one year to patients with advanced melanoma. Treatment will be divided into

immunologic adjuvant
nivolumab
ipilimumab
immunosuppressant
metastatic melanoma
  • 1 views
  • 26 Apr, 2022
  • 3 locations