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Found 42 clinical trials
Stepped Palliative Care Versus Early Integrated Palliative Care in Patients With Advanced Lung Cancer

This research study is evaluating ways to provide palliative care to patients who have recently been diagnosed with lung cancer

lung carcinoma
cancer
lung cancer
primary malignant neoplasm
advanced lung cancer
  • 8 views
  • 03 May, 2021
  • 2 locations
Novel Approach to Radiotherapy in Locally Advanced Lung Cancer Concomitant Navelbine

To investigate the effect of escalation of radiation dose to tumor and lymph nodes based on an inhomogeneous dose distribution controlled by FDG-PET positive areas compared to a standard homogeneous dose spread

advanced lung cancer
lung carcinoma
  • 7 views
  • 26 Jan, 2021
  • 7 locations
MEchanisms of Resistance in EGFR Mutated Nonpretreated Advanced Lung Cancer Receiving OSimErtib

Osimertinib is an epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) that is selective for both EGFR-TKI sensitizing and T790M resistance mutations in patients with non-small-cell lung cancer. The AURA 3 study (T790M-positive advanced non-small-cell lung cancer in progression after first-line EGFR-TKI therapy, shown that the median duration of progression-free …

growth factor
carcinoma
EGFR
osimertinib
stage iv non-small cell lung cancer
  • 6 views
  • 23 Jan, 2021
  • 15 locations
Elderly With Locally Advanced Lung Cancer: Deciding Through Geriatric Assessment on the Optimal Treatment Strategy

There is no detailed information available on benefits and harms of intensified treatment with concurrent RCHT among a subpopulation of elderly patients. Reliable tools are needed to distinguish the subgroup of fit patients from frail patients.

advanced lung cancer
lung carcinoma
  • 10 views
  • 23 Jan, 2021
  • 18 locations
Study of Chemotherapy Combination With Autologous Cell Immunotherapy in the Advanced Lung Cancer

This study evaluates the effect and safty of PD-1 monoclonal antibody-activated autologous peripheral blood T-lymphocyte (PD1-T) combined with docetaxel in the second-line treatment of IIIB/IIIC/IV non-small cell lung cancer. Half of participants receive PD1-T combined with docetaxel, while the other half will receive docetaxel.

  • 1 views
  • 22 Jan, 2021
  • 1 location
Endobronchial Ultrasound Guided Interstitial Photodynamic Therapy in Treating Patients With Locally Advanced Lung Cancer

This pilot trial studies the side effects of endobronchial ultrasound guided interstitial photodynamic therapy work in treating patients with lung cancer that has spread to nearby tissues or lymph nodes. Photodynamic therapy consists of injecting a light sensitive drug called a photosensitizer, such as porfimer sodium, into the vein, waiting …

international normalized ratio
endobronchial ultrasound
aptt
advanced lung cancer
  • 1 views
  • 29 Mar, 2021
  • 1 location
Brief Behavioral Intervention for Dyspnea in Patients With Advanced Lung Cancer

This research study is evaluating a behavioral intervention designed to help people with advanced lung cancer manage dyspnea (i.e., breathlessness or shortness-of-breath).

cancer
advanced lung cancer
lung cancer
small cell lung cancer, extensive stage
primary malignant neoplasm
  • 0 views
  • 26 Jan, 2021
Pembrolizumab (Immunotherapy Drug) in Combination With Guadecitabine and Mocetinostat (Epigenetic Drugs) for Patients With Advanced Lung Cancer.

The purpose of this study is to test the safety of a combination of three drugs, pembrolizumab, guadecitabine and mocetinostat. Pembrolizumab is a drug given by vein and all patients will receive the same dose. Guadecitabine and mocetinostat will be given at different doses to find out what effects, if …

cancer
hysterectomy
total bilirubin
monoclonal antibodies
advanced lung cancer
  • 152 views
  • 25 Jan, 2021
  • 3 locations
Functional Lung Avoidance SPECT-guided Radiation Therapy of Lung Cancer

Study aims to determine if functional lung avoidance based on perfusion single photon emission (SPECT)/CT scan, improves toxicity outcomes for patients with advanced lung cancer undergoing chemo

  • 0 views
  • 29 Jan, 2021
  • 2 locations
Moderate Hypofractionated Radiotherapy for Lung Cancer

The purpose of this study is to evaluate the incidences of Grade III and above radiation-reduced esophagitis and radiation-reduced pneumonia of patients with advanced lung cancer treated with

  • 0 views
  • 15 Mar, 2021
  • 1 location