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Found 162 clinical trials
Circulating Tumor DNA as Marker of Therapeutic Efficacy in Breast Cancer Patients

In nonmetastatic local advanced breast cancer patients, we are going to investigate whether circulating tumor DNA (ctDNA) detection can reflect the tumor response to neoadjuvant chemotherapy

breast cancer
cancer
advanced breast cancer
invasive breast cancer
  • 1 views
  • 22 Jan, 2021
  • 1 location
Level of HER2-neu Gene Amplification an Response to Trastuzumab

progression (TTP) in patients with HER2-positive advanced breast cancer treated with trastuzumab-containing regimens.

HER2
her2/neu-positive breast cancer
trastuzumab
  • 0 views
  • 07 Nov, 2020
  • 1 location
SENTINEL LYMPH NODE BIOPSY AFTER NEOADJUVANT CHEMOTHERAPY

study, the investigators evaluated factors affecting local recurrence and outcome in patients with locally advanced breast cancer (LABC), who underwent sentinel lymph node (SLN) with or without ALND

  • 0 views
  • 23 Jan, 2021
  • 1 location
Locoregional Surgery of the Primary Tumor in de Novo Stage IV Breast Cancer Patients

Current guidelines lack definitive evidences about the relative benefits of locoregional surgery for the primary tumor in de novo stage IV breast cancer. The aim of this study (SYSBTC-001) was to investigate the role of locoregional surgery for primary tumor in de novo stage IV breast cancer.

metastasis
primary lesion
breast cancer
cancer
stage iv breast cancer
  • 0 views
  • 25 Jan, 2021
  • 3 locations
Abemaciclib in Combination With Endocrine Therapy as First Line Therapy in Metastatic Breast Cancer Patients With Symp-tomatic Visceral Metastases or High Tumor Burden

Breast cancer is one of the most common cancers in women. 20-30 % of all breast cancer patients are faced with advanced disease, comprising both locally advanced breast cancer (LABC) and

  • 0 views
  • 31 Jan, 2021
  • 1 location
Circulating Osteocalcin-positive Cells in Breast Cancer Bone Metastasis

Bone metastasis (i.e. cancer cell spreading to bone) is the major clinical problem of advanced breast cancer patients. Bone metastasis is not curable nor preventable. Currently available

  • 0 views
  • 22 Jan, 2021
  • 2 locations
An EORTC Study Updating the QLQ-BR23 to BR45

subgroup of patients from the local/ locally advanced breast cancer group (who have had change in disease or treatment status after the first assessment) will be invited to complete a second set of

metastasis
combinations
female breast cancer
breast cancer
primary cancer
  • 0 views
  • 26 Jan, 2021
  • 1 location
Predictors of Response to Neoadjuvant Docetaxel-Carboplatin Chemotherapy for Patients With Stage II and III Triple Negative Breast Cancer

studies, whereas in selected cohorts of patients with advanced breast cancer or African-American ethnicity, TNBC may be diagnosed among as many as 23-28%. Patients with TN breast tumors treated

BRCA1
triple negative breast cancer
HER2
breast carcinoma
taxane
  • 0 views
  • 25 Jan, 2021
  • 1 location
A Phase IV Study to Collect Data on the Efficacy and Safety of RIBociclib in Older Women With Breastcancer

The RibOB study is a prospective, open lable, single arm trial which will evaluate the clinical efficacy, overall safety and tolerability of ribociclib in combination with letrozole in older women (70 years) with HR+/HER2- aBC and no prior hormonal treatment for advanced disease (as per approved indication).

progesterone receptor
cish
HER2
estrogen
letrozole
  • 0 views
  • 23 Jan, 2021
  • 1 location
Personalised Disease Monitoring in Metastatic Breast Cancer

Patients with metastatic breast cancer may respond well to treatment and metastases can remain stable for several years. Despite personalised medicine being increasingly used for diagnosis and treatment, follow-up still include radiological response evaluation every 3-4 months, which renders a significant number of 'unnecessary' exams for patients with long-term stable …

  • 0 views
  • 26 Jan, 2021
  • 7 locations