advanced renal cell carcinoma Clinical Research Trials

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A Multicenter, Open-Label, Randomized, Phase 3 Trial to Compare the Efficacy and Safety of Lenvatinib in Combination with Everolimus or Pembrolizumab Versus Sunitinib Alone in First Line Treatment of Subjects with Advanced Renal Cell Carcinoma

Subjects with Advanced Renal Cell Carcinoma

220 views
08 Nov, 2020
1 location

A Study to Evaluate MEDI5752 and Axitinib in Subjects With Advanced Renal Cell Carcinoma

The purpose of this study is to evaluate MEDI5752 in combination with axitinib.in subjects with advanced renal cell carcinoma.

5 views
17 Jan, 2021
17 locations

Decitabine Combined With Oxaliplatin in Patients With Advanced Renal Cell Carcinoma

The investigators reported previously that epigenetic activation of organic cation transporter (OCT2) by decitabine sensitizes RCC cells to oxaliplatin both in vitro and in xenografts. The objective of this phase II clinical trial is to investigate the efficacy and safety of sequential combination therapy with decitabine and oxaliplatin in patients …

myocardial infarction

cancer

oxaliplatin

platelet count

neutrophil count

1 views
11 Aug, 2019

Software Monitoring of Treatment Related Toxicities in Advanced Renal Cell Carcinoma

To determine if Carevive software, which monitors treatment-related toxicities and then generates self-care management plans for these symptoms, will be feasible to implement among patients with metastatic renal cell carcinoma (RCC). Additionally for collection of preliminary data on treatment-related toxicities, quality of life, distress level, and drug adherence.

1 views
19 Jan, 2021
1 location

Combined Alternating Sunitinib and Bevacizumab (Avastin ) in Advanced Renal Cell Carcinoma (CASA)

Combined sunitinib and bevacizumab in advanced renal cell carcinoma.

bevacizumab

carcinoma

renal function tests

brain metastases

metastasis

39 views
08 Nov, 2020
1 location

Dendritic Cell Immunotherapy Plus Standard Treatment of Advanced Renal Cell Carcinoma

in vitro transcribed (IVT) RNA from an autologous tumor specimen and CD40L RNA. CMN-001 is indicated for treatment of intermediate/poor risk patients with advanced renal cell carcinoma (RCC) in

0 views
30 Sep, 2020

Study of Front Line Therapy With Nivolumab and Salvage Nivolumab + Ipilimumab in Patients With Advanced Renal Cell Carcinoma

Phase II trial of nivolumab in 120 treatment nave patients with ccRCC.

82 views
16 Jan, 2021
12 locations

Study of the Combination of CM082 With Everolimus in Patients With mRCC

Advanced Renal Cell Carcinoma.

everolimus

cancer therapy

cancer

measurable disease

endocrine therapy

0 views
08 Nov, 2020
1 location

CM082 Combined With Everolimus in Chinese Patients With Metastatic Renal Cell Carcinoma

This randomized, double blind, phase 2/3 study is aimed to evaluate the efficacy and safety of CM082 in combination with everolimus in Chinese patients with advanced renal cell carcinoma. The

17 views
08 Nov, 2020
1 location

Tailored ImmunoTherapy Approach With Nivolumab in Subjects With Metastatic or Advanced Renal Cell Carcinoma

TITAN RCC (0216-ASG) is a Phase 2, open-label study of nivolumab monotherapy with additional nivolumab/ipilimumab "boost" cycles in previously untreated and pretreated (2nd line), advanced or metastatic renal cell carcinoma (mRCC) subjects with intermediate and high risk disease according to IMDC.