Found 101 clinical trials
Study of Quavonlimab (MK-1308) in Combination With Pembrolizumab (MK-3475) in Advanced Solid Tumors (MK-1308-001)
This study will assess the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of escalating doses of quavonlimab when used in combination with pembrolizumab in participants with advanced solid tumors.
- 774 views
- 22 Sep, 2021
- 56 locations
SentoClone Compared to Reference Treatment in Advanced Malignant Melanoma
The purpose of this study is to elucidate whether SentoClone® gives improved treatment responses in patients with advanced malignant melanoma in comparison to established reference
- 14 views
- 08 Nov, 2020
- 5 locations
FLX475 in Combination With Ipilimumab in Advanced Melanoma
This clinical trial is a Phase 2, open-label study to determine the anti-tumor activity of FLX475 in combination with ipilimumab in subjects with advanced melanoma previously treated with an
- 0 views
- 22 Sep, 2021
- 4 locations
A Trial of Pembrolizumab and Metformin Versus Pembrolizumab Alone in Advanced Melanoma
The purpose of this study is to evaluate the effectiveness and safety of the combination of Pembrolizumab (KEYTRUDA) and the investigational drug, Metformin.
- 0 views
- 27 Jan, 2021
- 1 location
Nab-PCE vs PC for MM After Failure of Anti-PD-1
This is a randomized controlled clinical trial of nab-paclitaxel + carboplatin Endostatin for advanced melanoma after failure of PD-1 therapy. The aim was to evaluate the efficacy
- 0 views
- 22 Jan, 2021
- 1 location
Adoptive Tumor-infiltrating Lymphocyte Transfer With Nivolumab for Melanoma
This study is to investigate safety and feasibility of a combination therapy of a tumor infiltrating lymphocytes (TIL) transfer with anti-programmed cell death protein (PD)-1 therapy in patients with metastatic melanoma that failed immunotherapy.Tumor-infiltrating lymphocytes will be expanded from resected melanoma samples from the patient and expanded TILs will be …
- 0 views
- 14 Aug, 2021
- 1 location
Combination Therapy With GEN0101 and Pembrolizmub in Advanced Melanoma Patients PIb/PII
advanced melanoma.
- 0 views
- 22 Jan, 2021
- 7 locations
A Study to Assess LBL-007 in Combination With Toripalimab in Subjects With Advanced Melanoma
This is a multi-center ,open-label, single-arm,dose-escalation,and extended phase I of LBL-007 in combination with Toripalimab. The study is designed to assess the safety, tolerability and efficacy of LBL-007 in combination with Toripalimab in the treatment of unresectable or metastatic melanoma(including Cutaneous melanoma, Acral melanoma, Mucosal melanoma, and melanoma of unknown …
- 0 views
- 07 Jun, 2021
- 3 locations
Safety and Efficacy of Selinexor in Combination With Pembrolizumab in Recurrent Advanced Melanoma
Approximately 40 participants with locally advanced or metastatic melanoma will be enrolled in 20 sites in the United States into 1 of the following 2 arms: Primary resistance to initial checkpoint inhibitor (CPI) therapy in Arm A and Acquired resistance to initial CPI therapy in Arm B. Participants who have …
- 0 views
- 19 Sep, 2021
- 8 locations
Cabozantinib and Pembrolizumab for Advanced Metastatic Melanoma
The study aims to evaluate the safety and preliminary efficacy of the combination of cabozantinib and pembrolizumab in advanced melanoma
- 0 views
- 22 Sep, 2021
- 1 location