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Found 389 clinical trials
Featured trial
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid Tumors

The purpose of this study is to evaluate the safety and tolerability, pharmacokinetics, pharmacodynamics, and early clinical activity of INCB099280 in participants with select solid tumors

  • 0 views
  • 19 Jun, 2022
  • 16 locations
Featured trial
A Phase 1/2 Trial of MRTX849 in Combination with TNO155 in Patients with Advanced Solid Tumors with KRAS G12C Mutation

Characterize the safety and tolerability, and evaluate Pharmacokinetics of MRTX849 in combination with TNO155 in patients with advanced solid tumor malignancies with KRAS G12C mutation.

advanced solid tumor
solid tumors
malignant solid tumor
solid tumor
  • 178 views
  • 19 Feb, 2021
  • 4 locations
  • 32 views
  • 07 Jan, 2022
  • 18 locations
A Phase 1 Study With ABBV-CLS-484 in Subjects With Locally Advanced or Metastatic Tumors

The study will assess the safety, PK, PD, and preliminary efficacy of ABBV-CLS-484 as monotherapy and in combination with a PD-1 targeting agent or with a or a vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitor (TKI). The trial aims to establish a safe, tolerable, and efficacious dose of …

  • 13 views
  • 08 Jul, 2022
  • 8 locations
A Phase I Study of AL8326 in Advanced Solid Tumor

Main purpose Objective to study the tolerance and safety of single and multiple administration of repeated 28-day cycles of AL8326 in patients with advanced solid tumor, observe the dose

  • 0 views
  • 24 May, 2021
  • 2 locations
A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABSK043 in Patients With Advanced Solid Tumor

This is a Phase 1, Open-Label Study of ABSK043 to Assess Safety, Tolerability, and Pharmacokinetics in Patients with Advanced Solid Tumor. Preliminary antitumor activity will also be

bone marrow procedure
solid tumor
neutrophil count
platelet count
  • 0 views
  • 16 May, 2022
  • 3 locations
A Phase I Study of BPI-16350 in Patients With Advanced Solid Tumor

This was an open-label Phase I study. The primary objective of the study was to assess safety, tolerability, efficacy, and pharmacokinetic characteristics of BPI-16350 in different dose groups.

  • 0 views
  • 08 Jul, 2022
  • 1 location
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-011 in Patients With Advanced Solid Tumor

This is an open-label phase 1 study with an escalation part and an expansion part.

  • 0 views
  • 11 Jul, 2022
  • 1 location
A Study to Evaluate the Tolerance, Efficacy and Pharmacokinetics of TQB3454 Tablets

This is a open-label, multicenter, phase I study to evaluate tolerance and pharmacokinetics of TQB3454 tablets in subjects with advanced solid tumor or hematologic tumor.

  • 0 views
  • 22 Mar, 2022
  • 4 locations
Double/Triple Combinations of AN2025, AN0025 and Atezolizumab in Advanced Solid Tumors

This is an open-label, multicenter, Phase 1a study to evaluate the safety, tolerability, PK and preliminary efficacy of AN2025 and AN0025 in double or triple combination treatments with Atezolizumab in patients with locally advanced/metastatic tumors.

  • 0 views
  • 22 Mar, 2022
  • 4 locations