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Found 37 clinical trials
Study of JS004 Combined With Toripalimab for Advanced Lung Cancer

This is an open-label phase I/II study to evaluate the safety, tolerability, pharmacokinetics and initial efficacy of JS004 injection combined with toripalimab in patients with advanced lung

  • 0 views
  • 17 Sep, 2021
  • 2 locations
Reqorsa (Quaratusugene Ozeplasmid) and Osimertinib in Patients With Advanced Lung Cancer Who Progressed on Osimertinib (Acclaim-1)

The purpose of this randomized study is to determine the safety and efficacy of Reqorsa (quaratusugene ozeplasmid, formerly known as GPX-001) added to osimertinib in NSCLC patients with activating EGFR mutations who have progressed while on treatment with osimertinib. Reqorsa consists of non-viral lipid nanoparticles that encapsulate a DNA plasmid …

EGFR
brain metastases
lung carcinoma
tyrosine
osimertinib
  • 0 views
  • 04 Oct, 2022
  • 5 locations
  • 0 views
  • 29 Sep, 2021
  • 7 locations
Stepped Palliative Care Versus Early Integrated Palliative Care in Patients With Advanced Lung Cancer (STEP PC)

This research study is evaluating ways to provide palliative care to patients who have recently been diagnosed with lung cancer

lung cancer
advanced lung cancer
primary malignant neoplasm
cancer
lung carcinoma
  • 8 views
  • 07 Oct, 2022
  • 3 locations
A Phase Ia/Ib, Open Label, Dose-escalation Study of the Combination of BI 907828 With BI 754091 (Ezabenlimab) and BI 754111 and the Combination of BI 907828 With BI 754091(Ezabenlimab) Followed by Expansion Cohorts, in Patients With Advanced Solid Tumors

, advanced lung cancer, and cancer in the stomach, bladder or bile ducts. The participants get a combination of 2 medicines called BI 907828 and ezabenlimab (also called BI 754091). BI 907828 is a so

liver metastasis
EGFR
targeted therapy
solid neoplasm
primary cancer
  • 6 views
  • 20 Oct, 2022
  • 12 locations
Early Integrated Telehealth Versus In-Person Palliative Care for Patients With Lung Cancer (REACH PC)

This research study is evaluating ways to provide palliative care to patients who have recently been diagnosed with lung cancer and their families.

cancer
lung cancer
lung carcinoma
primary malignant neoplasm
  • 219 views
  • 07 Apr, 2022
  • 19 locations
Advanced Lung Tumor Treated by Osimertinib Plus Anlotinib

This is a prospective, single arm, phase Ib/IIa study. Up to 25 patients will be enrolled into the study (Part A: 2-18; Part B: 7-19). The study has been designed to allow an investigation of the optimal combination dose and schedule whilst of Osimertinib plus Anlotinib in patients with EGFRm+, …

  • 2 views
  • 07 Mar, 2021
  • 1 location
Pembrolizumab in Elderly Patients With Advanced Lung Cancer

This is a multi-center phase II trial of intravenous (IV) Pembrolizumab MK-3475 in subjects older than 70 years with advanced Non-small cell Lung Cancer (NSCLC) expressing Programmed death-ligand 1 (PD-L1). 82 patients will be enrolled in this trial to examine the efficacy, the impact on geriatric assessments, the quality of …

EGFR
mk-3475
epidermal growth factor receptor
lung carcinoma
growth factor
  • 6 views
  • 11 May, 2022
  • 12 locations
Niraparib in Combination With Osimertinib in EGFR-Mutated Advanced Lung Cancer

This research study is studying a combination of drugs as a possible treatment for EGFR-Mutated Advanced Lung Cancer. The names of the study drugs involved in this study are Niraparib and

  • 0 views
  • 28 Jan, 2021
  • 3 locations
Novel Approach to Radiotherapy in Locally Advanced Lung Cancer Concomitant Navelbine®

To investigate the effect of escalation of radiation dose to tumor and lymph nodes based on an inhomogeneous dose distribution controlled by FDG-PET positive areas compared to a standard homogeneous dose spread

lung carcinoma
advanced lung cancer
  • 9 views
  • 10 May, 2022
  • 4 locations