Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 152 clinical trials
featured
HER2-negative advanced breast cancer

People with HER2 negative advanced breast cancer are asked to participate in a research study being conducted by Montefiore Medical Center.  

HER2
advanced breast cancer
  • 21 views
  • 02 Aug, 2019
  • 1 location
featured
Advanced Breast Cancer with Visceral Metastases

People with advanced breast cancer are asked to participate in a research study being conducted by White Plains Hospital.  

advanced breast cancer
  • 22 views
  • 02 Aug, 2019
  • 1 location
featured
A Randomized Phase III Trial of Endocrine Therapy plus Entinostat/Placebo in Postmenopausal Patients with Hormone Receptor-Positive Advanced Breast Cancer

A Randomized Phase III Trial of Endocrine Therapy plus Entinostat/Placebo in Postmenopausal Patients with Hormone Receptor-Positive Advanced Breast Cancer

advanced breast cancer
hormone therapy
breast cancer
endocrine therapy
  • 88 views
  • 23 Nov, 2020
  • 1 location
featured
HER2 Negative Advanced Breast Cancer

People with HER2 negative advanced breast cancer are asked to participate in a research study being conducted by Queens Hospital Center.  

HER2
advanced breast cancer
cancer
  • 27 views
  • 28 Oct, 2019
  • 1 location
The UK Plasma Based Molecular Profiling of Advanced Breast Cancer to Inform Therapeutic CHoices (plasmaMATCH) Trial

plasmaMATCH is a multi-centre phase IIa umbrella trial platform consisting of a ctDNA screening component and a therapeutic component. plasmaMATCH aims to assess whether ctDNA screening can be used to detect patient subgroups who will be sensitive to targeted therapies, and will also assess the safety and activity of the …

olaparib
her2/neu-positive breast cancer
locally advanced breast cancer
lhrh analogue
serum pregnancy test
  • 313 views
  • 22 Jan, 2021
  • 18 locations
Neoadjuvant Treatment of HER2 Positive Early High-risk and Locally Advanced Breast Cancer

n the present study the neoadjuvant approach with the anti-HER2 trastuzumab and pertuzumab combined with carboplatin and paclitaxel will be used to compare the Event-Free Survival (EFS) in regimens with and without atezolizumab. Following the neoadjuvant part of the study, after surgery all patients will continue to receive trastuzumab and …

progesterone receptor
sentinel node
sentinel lymph node biopsy
doxorubicin
paclitaxel
  • 17 views
  • 24 Jan, 2021
  • 51 locations
Endocrine Therapy Plus CDK4/6 in First or Second Line for Hormone (SONIA) Receptor Positive Advanced Breast Cancer

Given the uncertain benefit in efficacy of adding CDK 4/6 to first rather than second line endocrine treatment, the aim of this project is to evaluate whether the sequence of an aromatase inhibitor plus CDK 4/6 in first line followed by fulvestrant in second line is superior to the sequence …

lhrh agonist
gilbert's syndrome
metastasis
aromatase inhibitor
endocrine therapy
  • 71 views
  • 23 Jan, 2021
  • 72 locations
Sequential Neo-adjuvant Chemotherapy Followed by Capecitabine Vs. Conventional Adjuvant Chemotherapy in Breast Cancer

This study evaluates whether sequential neo-adjuvant chemotherapy plus surgery followed by Capecitabine could achieve additional benefits over traditional postoperative chemotherapy. In the study group, patients that do not achieve pathological complete response(pCR) will receive sequential neo-adjuvant chemotherapy followed by Capecitabine. In the control group, patients will be treated with postoperative …

capecitabine
carcinoma
renal function
breast cancer
cancer
  • 0 views
  • 21 Jan, 2021
  • 1 location
Digital Tomosynthesis Mammography and Digital Mammography in Screening Patients for Breast Cancer

This randomized phase III trial studies digital tomosynthesis mammography and digital mammography in screening patients for breast cancer. Screening for breast cancer with tomosynthesis mammography may be superior to digital mammography for breast cancer screening and may help reduce the need for additional imaging or treatment.

  • 2012 views
  • 24 Jan, 2021
  • 72 locations
Study Evaluating Abemaciclib + Aromatase Inhibitors in HR+ HER2- Advanced Breast Cancer Patients (HERMIONE-7)

The HERMIONE-7 trial is a phase II, single-arm, open-label, multicenter study in HR+, HER2- advanced breast cancer patients who have received HD-FUL as first-line endocrine treatment for their

progesterone receptor
aromatase inhibitor
metastasis
cish
progesterone
  • 0 views
  • 27 Jan, 2021
  • 49 locations