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Found 30 clinical trials
Featured trial
Re-assessment of diagnostic cortisol values for adrenal insufficiency using a highly specific cortisol assay

in the body’s stress response. Adrenal insufficiency is a condition in which the body's adrenal glands cannot produce enough cortisol. Symptoms of low cortisol can include fatigue, low blood pressure

Accepts healthy volunteers
  • 0 views
  • 08 Jan, 2022
  • 1 location
Randomized Trial of Sedative Choice for Intubation (RSI)

Among critically ill adults undergoing emergency tracheal intubation, one in five experience hypotension, cardiac arrest, or death. The sedatives used to rapidly induce anesthesia for emergency tracheal intubation have been hypothesized to effect cardiovascular complications and patient outcomes, but the optimal sedative medication for intubation of critically ill adults remains …

  • 0 views
  • 04 Oct, 2022
  • 1 location
Evaluation of a Nurse-led Program for the Prevention of Complications of Long-term Corticosteroid Therapy (COCORTICO)

. Such an approach should particularly include cortisonic osteoporosis prevention, infectious prevention including vaccination, prevention of adrenal insufficiency, promotion of physical activity, as

  • 0 views
  • 04 Oct, 2022
  • 1 location
SMART-ALD - A New Lifestyle Intervention to Improve Quality of Life in Women With X-linked Adrenoleukodystrophy (X-ALD)

fatty acids (VLCFA) for peroxisomal degradation, thus causing their toxic accumulation in body fluids and tissues. The clinical spectrum ranges from adrenal insufficiency without neurological symptoms

  • 0 views
  • 04 Oct, 2022
  • 2 locations
Congenital Adrenal Hyperplasia Once Daily Hydrocortisone Treatment (CareOnTIME)

This is a controlled, open study designed to compare the effects of dual-release hydrocortisone preparations versus conventional glucocorticoid therapy on clinical, anthropometric parameters, metabolic syndrome, hormonal profile, bone status, quality of life, reproductive, sexual and psychological functions and treatment compliance in patients affected by congenital adrenal hyperplasia due to 21 …

prednisone
21-ohd
glucocorticoids
cortisone acetate
dexamethasone
  • 56 views
  • 14 Apr, 2022
  • 1 location
Stress Hydrocortisone In Pediatric Septic Shock (SHIPSS)

SHIPSS is a multi-institutional, prospective, controlled, randomized, double-blinded interventional trial that will examine the potential benefits and risks of adjunctive hydrocortisone prescribed for children with fluid and vasoactive-inotropic refractory septic shock. It is hypothesized that adjunctive hydrocortisone will significantly reduce the proportion of children with poor outcomes, defined as death …

norepinephrine
inotropic agent
antimicrobial agent
continuous infusion
  • 29 views
  • 04 Oct, 2022
  • 43 locations
Prevalence of Hypoglycaemia in Congenital Adrenal Insufficiency

Children with congenital primary and secondary adrenal insufficiency, who are deficient in cortisol, are at risk for hypoglycaemia, irrespective of appropriate hydrocortisone treatment, which

  • 0 views
  • 25 Jan, 2021
  • 1 location
Updated Diagnostic Cortisol Values for Adrenal Insufficiency

The purpose of this study is to determine the cortisol levels that most accurately diagnose a patient with adrenal insufficiency, a condition in which cortisol levels are too low for daily

Accepts healthy volunteers
  • 0 views
  • 17 Mar, 2022
  • 1 location
Mifepristone Dynamic Testing for Diagnosis for Central Adrenal Insufficiency

The researchers propose the use of mifepristone as an alternative way to test for Central Adrenal Insufficiency (CAI). They want to assess the feasibility of recruitment and the efficacy of the

  • 0 views
  • 30 May, 2022
  • 1 location
Chronocort Versus Plenadren Replacement Therapy in Adults With Adrenal Insufficiency (CHAMPAIN)

participants aged 18 years and over, diagnosed with primary Adrenal Insufficiency (AI).

adrenaline
  • 0 views
  • 04 Oct, 2022
  • 6 locations