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Found 11 clinical trials
An Oral GnRH Antagonist to Treat Mild Autonomous Cortisol Excess (MACE) Due to Adrenal Adenomas in Postmenopausal Women

endometriosis by decreasing the body's production of sex hormones. Growth of adrenal adenomas is thought to be driven by such sex hormones. Therefore, by decreasing production of these hormones, the study team

  • 0 views
  • 16 Sep, 2021
  • 1 location
Adrenalectomy Versus Follow-up in Patients With Subclinical Cushings Syndrome (AUSC)

study is, that surgery of the adrenal adenoma responsible for the increased secretion of cortisol, will in part cure or ameliorate the metabolic syndrome.

  • 30 views
  • 24 Mar, 2022
  • 3 locations
Efficacy and Safety of Relacorilant in Patients With Cortisol-Secreting Adrenal Adenomas (GRADIENT)

This is a Phase 3, randomized, double-blind, placebo-controlled study to assess the efficacy, and safety of relacorilant to treat hypercortisolism in patients with cortisol-secreting adrenal

adrenal adenoma
adenoma
relacorilant
hypertension
hypercortisolism
  • 0 views
  • 23 Apr, 2022
  • 48 locations
Radiofrequency Endoscopic Ablation With Ultrasound Guidance: a Non-surgical Treatment for Aldosterone-producing Adenomas (FABULAS)

High blood pressure (hypertension) causes strokes and heart attacks. While most patients need long-term treatment with pills, some have a cause which can be removed, curing the hypertension. The commonest curable cause is a benign nodule in one of the hormone glands, the adrenals. About one in 20 patients have …

aldosterone
renin
radiofrequency ablation
heart attacks
adenoma
  • 37 views
  • 03 Mar, 2022
  • 2 locations
Gallium-68 Labeled Pentixafor PET/CT in Adrenal Masses

-functioning adrenal adenomas. Besides, CXCR4 is also hardly expressed by the tumor cells in paragangliomas. 68Ga-pentixafor, a CXCR4-specific PET tracer, may therefore be effective for the evaluation of the

  • 0 views
  • 07 May, 2021
  • 1 location
MACS and Healthy Volunteers Bone Study

Adrenal adenoma is detected in 5-7% of adults and demonstrates mild autonomous cortisol secretion (MACS, dexamethasone suppression test >1.8 mcg/dl) in 50% of individuals with adenoma

Accepts healthy volunteers
  • 52 views
  • 06 May, 2022
  • 1 location
China Adrenal Disease Registry (CASE)

Epidemiologic studies have revealed a tremendous increase in the prevalence of adrenal associated disease and related mortality worldwide. In order to meet all the therapeutic challenges in adrenal disease in China, CASE was founded in 2020. The objective of CASE is to launch an adrenal disease management model based on …

pheochromocytoma
adrenal pheochromocytoma
adrenaline
  • 0 views
  • 23 Mar, 2022
Performances on Cognitive Functions and Brain Function and Follow-up After Different Treatments in Patients With Autonomous Cortisol Secretion: a Single-center, Prospective, Observational Study

This is a single center, prospective, observational study to explore and evaluate the differences on cognitive function and brain function by functional-MRI in autonomous cortisol secretion patients, and the different treatments methods on the cognitive function and brain function in patients with autonomous cortisol secretion

Accepts healthy volunteers
  • 0 views
  • 12 May, 2022
Impact of Adrenal IncidenTalomas and Possible Autonomous Cortisol Secretion on Cardiovascular and Metabolic Alterations

The investigators hypothesize that cardiovascular and metabolic alterations can occur in patients with adrenal adenomas and possible Autonomous Cortisol Secretion (pACS). Investigators

  • 22 views
  • 23 Jan, 2021
  • 1 location
Evaluation of New Diagnostic Indicator of Subclinical Hypercortisolism

The purpose of this study is to evaluate the serum dehydroepiandrosterone sulfate in subclinical hypercortisolism

Accepts healthy volunteers
  • 0 views
  • 02 May, 2022
  • 1 location