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Found 264 clinical trials
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A Randomized Phase III Double Blinded Placebo Controlled Trial of Aspirin as Adjuvant Therapy for Node Positive HER2 Negative Breast Cancer: The ABC Trial (Alliance A011502)

A Randomized Phase III Double Blinded Placebo Controlled Trial of Aspirin as Adjuvant Therapy for Node Positive HER2 Negative Breast Cancer: The ABC Trial (Alliance A011502)

erbb2
breast cancer
HER2
  • 560 views
  • 03 Dec, 2020
  • 1 location
featured
A Randomized Phase III Trial of Adjuvant Therapy Comparing Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel with or without Carboplatin for Node-Positive or High-Risk Node-Negative Triple-Negative Invasive Breast Cancer

A Randomized Phase III Trial of Adjuvant Therapy Comparing Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel with or without Carboplatin for Node-Positive or High-Risk Node-Negative

doxorubicin
invasive breast cancer
paclitaxel
carboplatin
cyclophosphamide
  • 66 views
  • 03 Dec, 2020
  • 1 location
featured
  • 228 views
  • 08 Nov, 2020
  • 1 location
Oral Cancer Adjuvant Therapy (OCAT) Trial

To demonstrate whether addition of Concurrent chemotherapy to post-operative adjuvant radiotherapy OR shortening of duration of post-operative radiotherapy, by administering 6 fractions / week instead of 5 fractions / week improves local-regional control and / or overall survival in high risk, locally advanced, resectable, squamous cell carcinoma of oral cavity.

squamous cell carcinoma
chemoradiotherapy
adjuvant therapy
carcinoma
carcinoma of oral cavity
  • 60 views
  • 07 Nov, 2020
  • 1 location
Selective Targeting of Adjuvant Therapy for Endometrial Cancer (STATEC)

The primary aim of this trial is to determine whether lymphadenectomy, used to restrict adjuvant therapy (other than vaginal brachytherapy) to node positive women, results in a non-inferior

carcinosarcoma
mucinous adenocarcinoma
adenocarcinoma
lymphadenectomy
hysterectomy
  • 33 views
  • 08 Nov, 2020
PENN-Surveillance Markers of Utility for Recurrence After (Neo)Adjuvant Therapy for Breast Cancer

This is a single center, prospective cross-sectional study of women who have completed therapy for primary breast cancer within 5 years of diagnosis and are at increased risk for relapse. Patients will undergo screening bone marrow aspirate to test for presence of disseminated tumor cells (DTCs) Patients who harbor DTCs …

invasive breast cancer
estrogen receptor
tumor cells
adjuvant therapy
progesterone receptor
  • 3 views
  • 24 Sep, 2020
  • 1 location
POSNOC - A Trial Looking at Axillary Treatment in Early Breast Cancer

adjuvant therapy alone is no worse than adjuvant therapy plus axillary treatment, in terms of axillary recurrence within 5 years. Stratification: Institution, Age (<50, 50), Breast-conserving

hormone therapy
mastectomy
estrogen receptor
breast-conserving surgery
endocrine therapy
  • 1778 views
  • 12 Apr, 2020
  • 50 locations
Brief Title: Study of Efficacy and Safety of Canakinumab as Adjuvant Therapy in Adult Subjects With Stages AJCC/UICC v. 8 II-IIIA and IIIB (T>5cm N2) Completely Resected Non-small Cell Lung Cancer Acronym: CANOPY-A

The primary purpose of the study is to compare the efficacy and safety of canakinumab versus placebo as adjuvant therapy in adult subjects with stages AJCC/UICC v. 8 II -IIIA and the subset of

systemic therapy
alopecia
  • 645 views
  • 26 Oct, 2020
  • 390 locations
Pembrolizumab Versus Placebo Following Surgery and Radiation in Participants With Locally Advanced Cutaneous Squamous Cell Carcinoma (MK-3475-630/KEYNOTE-630)

This is a randomized, double-blind, study that compares pembrolizumab with placebo given as adjuvant therapy in participants with high-risk locally advanced cutaneous squamous cell carcinoma (LA

pembrolizumab
adjuvant therapy
cancer
mk-3475
  • 69 views
  • 14 Jan, 2021
  • 131 locations
Circulating Tumour DNA Based Decision for Adjuvant Treatment in Colon Cancer Stage II Evaluation

The CIRCULATE study evaluates the adjuvant therapy in patients with colon cancer UICC stage II. The primary aim of the study is to compare the disease free survival in patients who are positive

  • 0 views
  • 12 Aug, 2020