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Found 86 clinical trials
Efficacy and Safety of Pimavanserin as Adjunctive Treatment for the Negative Symptoms of Schizophrenia

To evaluate the efficacy and safety of adjunctive pimavanserin compared with adjunctive placebo in the treatment of negative symptoms of schizophrenia

cariprazine
asenapine
lurasidone
antipsychotics
adjunctive treatment
  • 20 views
  • 28 Oct, 2021
  • 86 locations
Remote Ischemic Conditioning in Patients With Acute Stroke (RESIST) (RESIST)

Our primary aim is to investigate whether remote ischemic conditioning (RIC) as an adjunctive treatment can improve long-term recovery in acute stroke patients as an adjunct to standard

ischemia
acute stroke
stroke
limb ischemia
adjunctive treatment
  • 16 views
  • 26 Mar, 2022
  • 4 locations
A Study of Brexpiprazole in Patients With Major Depressive Disorder

The purpose of this 14 week, randomized, double-blind, placebo controlled study is to assess the safety and efficacy of brexipiprazole to placebo as adjunctive treatment to an assigned open

antidepressants
major depressive disorder
major depressive disorder, recurrent episode
brexpiprazole
adjunctive treatment
  • 5 views
  • 14 Feb, 2022
  • 1 location
Safety of REL-1017 for Major Depressive Disorder (RELIANCE-OLS)

This is a 1-year open-label study to access the safety of REL-1017 once daily (QD) as an adjunctive treatment of Major Depressive Disorder. Study participants will continue to take their current

  • 16 views
  • 28 May, 2022
  • 90 locations
A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy

The purpose of this study is to assess the efficacy of Seltorexant compared with placebo as adjunctive therapy to an antidepressant in improving depressive symptoms in participants with major depressive disorder with insomnia symptoms (MDDIS) who have had an inadequate response to current antidepressant therapy with a selective serotonin reuptake …

  • 214 views
  • 10 May, 2022
  • 76 locations
A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant and Long-term Safety Extension Treatment With Seltorexant

The purpose of this study is to assess the efficacy of seltorexant compared with placebo as adjunctive therapy to an antidepressant in improving depressive symptoms in participants with major depressive disorder with insomnia symptoms (MDDIS) who have had an inadequate response to current antidepressant therapy with an selective serotonin reuptake …

  • 73 views
  • 23 Apr, 2022
  • 89 locations
A Study of Seltorexant Compared to Quetiapine XR as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy

The purpose of this study is to assess the efficacy of seltorexant compared with quetiapine extended-release (XR) as adjunctive therapy to an antidepressant drug in treatment response in participants with major depressive disorder with insomnia symptoms (MDDIS) who have had an inadequate response to current antidepressant therapy with a selective …

selective serotonin reuptake inhibitors
fluvoxamine
paroxetine
venlafaxine
fluoxetine
  • 1278 views
  • 08 Jun, 2022
  • 117 locations
A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adolescents With Major Depressive Disorder Who Have an Inadequate Response to Selective Serotonin Reuptake Inhibitor (SSRI) and Psychotherapy

The purpose of this study is to assess the safety and tolerability of Seltorexant as adjunctive therapy to an antidepressant in adolescents with major depressive disorder (MDD) in the short-term compared with placebo.

  • 1 views
  • 30 Jun, 2022
  • 12 locations
Exercise as Adjunctive Treatment for Refractory Epilepsy

The purpose of this research study is to determine whether a 12-week telehealth aerobic exercise intervention is feasible in people with epilepsy. The study team will also gather information on the effect of the intervention on sleep and stress as mediators of seizure frequency, well as effects on epilepsy and …

adjunctive treatment
seizure
generalized epilepsy
  • 0 views
  • 24 Mar, 2022
  • 1 location
OMT as an Adjunctive Treatment in MDD

participants will be receiving OMT 1x/week for 8 weeks. Each appointment with be a duration of 30 minutes. Patients will be required to fill out PHQ-9 and SSS-8 questionnaires before beginning the study and following the conclusion of the study.

  • 0 views
  • 25 May, 2022
  • 1 location