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Found 83 clinical trials
Featured trial
This clinical study will measure the effectiveness of a new adjunctive treatment for people with type 1 diabetes.

This clinical study will measure the effectiveness of a new adjunctive treatment for people with type 1 diabetes.

  • 276 views
  • 23 Nov, 2020
  • 1 location
Featured trial
A double blind placebo controlled multicenter study of investigational medication as adjunctive treatment to a antidepressant in adults with Major Depressive Disorder.

A double blind placebo controlled multicenter study of investigational medication as adjunctive treatment to a antidepressant in adults with Major Depressive Disorder.

  • 578 views
  • 23 Nov, 2020
  • 1 location
Featured trial
A Phase 2a Randomized, Double-blind, Placebo-Controlled, Parallel-Group, Multi-center Study Investigating the Efficacy, Safety, Tolerability and Pharmacokinetics of JNJ-XXX in Subjects with Major Depressive Disorder

A study to evaluate the efficacy of JNJ-XXX compared to placebo when administered as adjunctive treatment in subjects with MDD partially responsive to SSRI/SNRI treatment in terms of reduction of

depressed mood
selective serotonin reuptake inhibitors
depressive symptoms
  • 75 views
  • 23 Nov, 2020
  • 1 location
Featured trial
A Double-Blind, Placebo-Controlled Study of Cariprazine as an Adjunct to Antidepressants in the Treatment of Patients With Major Depressive Disorder Who Have Had an Indadequate Response to Antidepressants Alone

A study to evaluate the efficacy, safety, and tolerability of cariprazine compared with placebo as an adjunctive treatment to ongoing antidepressant therapy in patients with major depressive

antidepressant therapy
depressive disorder
antidepressants
  • 112 views
  • 23 Nov, 2020
  • 1 location
Featured trial
An Efficacy and Safety Study of Sirukumab in Participants With Major Depressive Disorder

An Efficacy and Safety Study of Sirukumab in Participants With Major Depressive Disorder

  • 394 views
  • 23 Nov, 2020
  • 1 location
A Study of CLE-100 (Oral Esketamine) in Addition to Standard Antidepressant Drug for Major Depressive Disorder - CLEO Study

The clinical trial is a Phase 2, double-blind, randomized, placebo controlled study in Major Depressive Disorder (MDD) participants currently treated with antidepressant therapy. The objective of the study is to assess CLE-100 for the treatment of MDD in participants currently treated with standard antidepressant therapy.

  • 328 views
  • 18 May, 2022
  • 32 locations
Minocycline as Adjunctive Treatment for Treatment Resistant Depression (MINDEP2)

Major depressive disorder (MDD) is a leading cause of disability worldwide. Up to 50% of patients experience treatment resistant depression (TRD), which accounts for a vast majority of disease burden. Current medications for TRD have limited efficacy and can be associated with intolerable side effects. Therefore, there is a need …

psychosis
a 12
depressive disorder
sertraline
adjunctive treatment
  • 108 views
  • 12 May, 2022
  • 1 location
Dysport as an Adjunctive Treatment to Bracing in the Management of Adolescent Idiopathic Scoliosis

This study evaluates the combined effect of botulinum toxin A (administered as Dysport (Ipsen Pharmaceuticals)) and bracing in children with adolescent idiopathic scoliosis. Two thirds of patients will be treated with Dysport and bracing, while the remaining patients will be treated with placebo and bracing.

botulinum toxin
adjunctive treatment
  • 4 views
  • 01 Oct, 2021
  • 1 location
Deep Brain Stimulation Effects In Patients With Opioid Use Disorder

This is a pilot study to evaluate the safety and efficacy of deep brain stimulation (DBS) of the nucleus accumbens (NAc) as adjunctive treatment for treatment-refractory opioid use disorder

  • 0 views
  • 14 Mar, 2022
  • 1 location
Endovascular Embolization of Chronic Subdural Hematomas After Surgery (ENCLOSURE)

has recently been proposed as an alternative or adjunctive treatment to surgery. The investigators hypothesize that early post operative endovascular treatment can reduce the recurrence rate in high

  • 0 views
  • 07 Apr, 2022
  • 1 location