Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 217 clinical trials
Fibroblast Before and After Neoadjuvant Chemo-radiotherapy in Patient With Locally Advanced Rectal Adenocarcinoma (FibroRect)

Single center interventional study to explore activity of fibroblasts in the tumor and away in the healthy rectal tissue.

  • 2 views
  • 21 Apr, 2022
  • 3 locations
Non-Operative Management and Early Response Assessment in Rectal Cancer (NOM-ERA)

prospectively evaluated in non-operative management for patients with non-metastatic rectal adenocarcinoma.

  • 0 views
  • 07 Oct, 2022
  • 4 locations
Multicentric Phase II-III Study Evaluating the Tailored Management of Locally-advanced Rectal Carcinoma After a Favorable Response to Induction Chemotherapy (GRECCAR14)

Locally advanced rectal carcinoma raise the issue of both the oncological control, local and general, and the therapeutic morbidity. Surgery alone can cure only one out of two patients

total mesorectal excision
oxaliplatin
irinotecan
carcinoma
capecitabine
  • 0 views
  • 23 Oct, 2022
  • 14 locations
Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps (FORTE)

This trial examines colorectal cancer incidence in participants with 1 to 2 non-advanced adenomas randomized to surveillance colonoscopy at 10 years compared to participants randomized to surveillance colonoscopy at 5 and 10 years.

  • 7 views
  • 22 Apr, 2022
  • 157 locations
Artificial Intelligence Assists Surgeons' Decision Making

This study will evaluate whether artificial intelligence technique reduces the temporary ileostomy rate in patients with rectal cancer who receive anterior resection.

total mesorectal excision
adenocarcinoma
  • 0 views
  • 24 Sep, 2021
  • 1 location
Comparison of the Pathological Effect Between 2 and 4 Cycles Neoadjuvant CAPOX for Low/Intermediate Risk II/III Rectal Cancer (COPEC)

To compare the pathological effect between 2 cycles and 4 cycles of Capox regimen as neoadjuvant chemotherapy for low/ intermediate risk stage II/III rectal cancer.

oxaliplatin
metastasis
capecitabine
adenocarcinoma
  • 0 views
  • 18 Apr, 2022
  • 3 locations
Prospectively Randomized Control Clinical Trial of FOLFOXIRI Preoperative Chemotherapy Alone on Rectal Cancer in Local Advance Comparing to Oral Capecitabine Combined With Long-term Radiation

Preoperative radiation and chemotherapy is the standard treatment for local advanced rectal cancer. The addition of oxaliplatin to capecitabine combined with radiotherapy does not improve local control and long-term survival. Most importantly,chemoradiotherapy significantly increased surgical complication and poor long-term quality of life .In the absence of effective measures of predicting …

rectal surgery
metastasis
obstruction
xelox
adenocarcinoma of rectum
  • 4 views
  • 14 Feb, 2022
Low or High Ligation of the IMA With Apical Lymph Node Dissection in Rectal Cancer Laparoscopic Surgery

Laparoscopy colon surgery is accepted worldwide in the recent years. But there is still argument on the effect of laparoscopy rectal surgery. Laparoscopy has advantages on showing the inferior mesenteric artery (IMA), protection of autonomic nerve, low rectal anastomosis, and total mesorectum excision. However, debate on the level of IMA …

rectal surgery
metastasis
general anesthesia
rectal anastomosis
adenocarcinoma
  • 0 views
  • 25 Feb, 2022
  • 1 location
Short-term Outcomes of Full Bowel Preparation (MBP+OA) for Rectal Resections for Cancer Versus MBP Alone (REPCA)

The purpose of the study is to determine if short-term outcomes of rectal resections after full bowel preparation (mechanical bowel preparation plus oral antibiotics) are superior to rectal resections with only mechanical bowel preparation.

adenocarcinoma
proctectomy
  • 1 views
  • 18 Oct, 2022
  • 7 locations
Preoperative FOLFOX Versus Postoperative Risk-adapted Chemotherapy in Patients With Locally Advanced Rectal Cancer

This is a multicenter, prospective, randomized, stratified, controlled, open-label study comparing preoperative FOLFOX versus postoperative risk-adapted chemotherapy in patients with locally advanced rectal cancer and low risk for local failure

oxaliplatin
adenocarcinoma
xelox
capecitabine
folfox regimen
  • 0 views
  • 04 Oct, 2022
  • 1 location