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Found 216 clinical trials
XELOX+Bevacizumab Followed by Capecitabine+Bevacizumab+Radiotherapy as Neoadjuvant Treatment of Locally Advanced Rectal Adenocarcinoma

The purpose of this study is to determine the pathological complete response rate of addition of bevacizumab to induction therapy (xelox) and concomitant treatment (capecitabine+radiotherapy), followed by surgery.

adenocarcinoma
bevacizumab
renal function
xelox
liver metastases
  • 7 views
  • 07 Nov, 2020
  • 1 location
Fibroblast Before and After Neoadjuvant Chemo-radiotherapy in Patient With Locally Advanced Rectal Adenocarcinoma

Single center interventional study to explore activity of fibroblasts in the tumor and away in the healthy rectal tissue.

  • 2 views
  • 22 Feb, 2021
  • 4 locations
Short-course Radiation Followed by mFOLFOX-6 Plus COMPOUND 2055269 for Locally-advanced Rectal Adenocarcinoma

The purpose of this study is to show that the addition of COMPOUND 2055269, an immunotherapeutic drug, to Folfox chemotherapy will improve the pathologic complete response rate in patients with locally advanced rectal cancer.

  • 31 views
  • 23 Jan, 2021
  • 4 locations
INNATE: Immunotherapy During Neoadjuvant Therapy for Rectal Cancer

Determine the complete pathologic complete response (pCR) rate in patients with locally advanced rectal adenocarcinoma.

  • 0 views
  • 10 Jul, 2021
  • 2 locations
Non-Operative Management and Early Response Assessment in Rectal Cancer

prospectively evaluated in non-operative management for patients with non-metastatic rectal adenocarcinoma.

  • 0 views
  • 06 Jul, 2021
  • 5 locations
IMRT-SIB and Capecitabine in Preoperative Rectal Cancer Treatment

potentially better response to treatment. In advanced rectal adenocarcinoma excellent response to preoperative radiochemotherapy with complete eradication of the primary tumor observed in the

adenocarcinoma
platelet count
renal function
primary tumor
cancer
  • 3 views
  • 08 Nov, 2020
  • 1 location
Concurrent Chemoradiation Versus Wide Pelvic Lymphadenectomy for Advanced Rectal Cancer

Based on the neurophysiology, it is well known that sympathetic nerves control the ejaculatory function and bladder neck closure. In contrast, the parasympathetic nerves control penile erection and bladder wall contraction. Because of the difference in cultural background of the patients and training background of the physicians between Western and …

adenocarcinoma
conventional surgery
rectal carcinoma
  • 3 views
  • 07 Nov, 2020
  • 1 location
Laparoscopy-Assisted Surgery for Carcinoma of the Low Rectum

The purpose of this study is to evaluate the safety and oncological feasibility of laparoscopy-assisted surgery for low rectal carcinoma compared with open surgery.

adenocarcinoma
proctoscopy
carcinoma
cancer
curative surgery
  • 0 views
  • 21 Jan, 2021
  • 1 location
Comparison of the Pathological Effect Between 2 Cycles and 4 Cycles Neoadjuvant CAPOX for Low/Intermediate RC

To compare the pathological effect between 2 cycles and 4 cycles of Capox regimen as neoadjuvant chemotherapy for low/ intermediate risk stage II/III rectal cancer.

adenocarcinoma
oxaliplatin
capecitabine
metastasis
  • 0 views
  • 04 Aug, 2021
  • 3 locations
Conventional Laparoscopic APR Versus Laparoscopic APR With Transabdominal Individualized Levator Transection

This study is designed to compare the short-term and long-term benefits between conventional laparoscopic abdominoperineal resection (APR) and laparoscopic APR with transabdominal individualized levator transection (TILT).

body mass index
abdominoperineal resection
metastasis
  • 0 views
  • 21 Jan, 2021
  • 1 location