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Found 27 clinical trials
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Metastatic Colorectal Cancer with wild-type KRAS tumors.

Metastatic Colorectal Cancer with wild-type KRAS tumors.

  • 270 views
  • 25 Mar, 2021
  • 1 location
Development of Clinical and Biological Database in Colorectal Cancer (CIRCUS)

Creation of circulating cancer cell-lines and caracterisation of these cell-lines which will be collected before any treatment in patients with metastatic colon adenocarcinoma

adenocarcinoma
cancer
metastatic colorectal cancer
  • 1 views
  • 19 Feb, 2022
  • 1 location
Phase II Study of Olaparib in Subjects With Advanced Pancreatic Acinar Cell Carcinoma

Background Pancreatic Acinar Cell Carcinoma (PACC) is a rare pancreatic tumor. People with PACC usually present with advanced disease, and their prognosis is poor. Researchers want to learn if a cancer drug called olaparib can help. Objective To see if olaparib is an effective treatment for PACC. Eligibility People aged …

  • 0 views
  • 20 Sep, 2022
  • 1 location
Randomised Study Evaluating Adjuvant Chemotherapy After Resection of Stage III Colonic Adenocarcinoma in Patients of 70 and Over (ADAGE)

Colorectal cancer occurs mainly in elderly patients. Recent estimation showed that in France more than 50% of the patients diagnosed with a colorectal cancer are 70 years old or more. Adjuvant chemotherapy has demonstrated a benefit on disease-free survival and overall survival after a stage III colon cancer resection. Nevertheless …

stage iii colon cancer
oxaliplatin
colon cancer
primary tumor
capecitabine
  • 31 views
  • 07 Apr, 2022
  • 137 locations
Phase II/III Study of Circulating Tumor DNA as a Predictive Biomarker in Adjuvant Chemotherapy in Patients With Stage IIA Colon Cancer (COBRA)

This phase II/III trial studies how well circulating tumor deoxyribonucleic acid (ctDNA) testing in the blood works in predicting treatment for patients with stage IIA colon cancer after surgery. ctDNA are circulating tumor cells that are shed by tumors into the blood. Finding ctDNA in the blood means that there …

oxaliplatin
leucovorin
calcium
international normalized ratio
absolute neutrophil count
  • 0 views
  • 17 Sep, 2022
  • 627 locations
Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps (FORTE)

This trial examines colorectal cancer incidence in participants with 1 to 2 non-advanced adenomas randomized to surveillance colonoscopy at 10 years compared to participants randomized to surveillance colonoscopy at 5 and 10 years.

  • 7 views
  • 22 Apr, 2022
  • 157 locations
Randomized Trial of Standard Chemotherapy Alone or Combined With Atezolizumab as Adjuvant Therapy for Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

This phase III trial studies combination chemotherapy and atezolizumab to see how well it works compared with combination chemotherapy alone in treating patients with stage III colon cancer and deficient deoxyribonucleic acid (DNA) mismatch repair. Drugs used in combination chemotherapy, such as oxaliplatin, leucovorin calcium, and fluorouracil, work in different …

immunosuppressive
stage iii colon cancer
oxaliplatin
mmr protein
pulmonary disease
  • 1145 views
  • 15 Sep, 2022
  • 546 locations
LDLT in Non Resectable Colo-rectal Cancer Liver Metastasis (LIVERMORE)

This study is an interventional open label prospective study that aims to assess both overall and disease-free survival of patients treated with LDLT for unresectable CRLM. Secondary outcomes are graft survival and donor outcomes in terms of safety and quality of life. Donor selection is performed according to the currently …

  • 0 views
  • 24 Mar, 2022
  • 1 location
Intracorporeal Versus Extracorporeal Anastomosis In Laparoscopic Right Colon Resection

STUDY DESIGN This study is a prospective, randomized, multi-center study comparing intracorporeal versus extracorporeal anastomosis in performing laparoscopic right colectomy. The study subjects will be randomly assigned to 1. intracorporeal anastomosis (experimental group) 2. extracorporeal anastomosis (control group) with 1:1 manner. After surgery the subjects will be followed up at …

  • 0 views
  • 20 Oct, 2021
  • 1 location
  • 0 views
  • 16 Jun, 2022
  • 1 location