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Found 392 clinical trials
Nicotinic Receptor Genetic Variation and Alcohol Reward

Background People with the brain disease AUD (alcohol use disorder) have a serious problem with drinking. Researchers want to study how different people react to alcohol, and how genes affect this. They will focus on a nicotine receptor gene that may increase a person s AUD risk. Objectives To see …

Accepts healthy volunteers
  • 29 Oct, 2022
  • 1 location
Suicide Re Attempts in Young Adults After First Suicide Attempt : Socio-demographic, Clinical and Biological Correlates (SURAYA)

Suicide is the second leading cause of death among people aged 15 to 24 (WHO, 2014). After a first suicide attempt, the 18 to 25 years old would be very likely to repeat the act: 25 to 31% would make a new attempt in the following year (Christiansen et al, …

  • 13 Apr, 2022
  • 1 location
Using Telehealth to Improve Outcomes in Veterans at Risk for Suicide

Overview. The investigators will randomize 120 Veterans in this 3-site trial over 16 months. Eligible Veterans will include those to be discharged for a hospitalization for suicidal ideation. Baseline data collection and randomization will occur at discharge. The 3 month intervention will have study assessments at 2, 4, 8, and …

depressed mood
depressive symptoms
  • 18 May, 2022
  • 2 locations
Ball Blankets on Insomnia in Depression in Outpatient Clinics

The objective of the study is to examine the efficacy of Protac Ball BlanketsTM (PBB) and specifically if the PBB will extend the total sleep time of patients with insomnia due to depression in two psychiatric outpatient clinics at Aarhus University Hospital and Odense University Hospital. Furthermore, it will be …

  • 04 Jun, 2022
  • 2 locations
The Effects of Schema Therapy in Outpatient Forensic Mental Health Care: a Single Case Multiple-baseline Study. (STOFSCED)

Forensic psychiatry aims at reducing recidivism risk by treating mental or psychiatric problems. In forensic psychiatry approximately between 42 and 84% of the patients have PDs (Logan, 2020; de Ruiter, 2009). Individuals with PDs have an increased risk of violence and a higher recidivism risk than offenders without PDs (Yu …

  • 07 Oct, 2022
Cigar Packaging Study (CPS)

The purpose of this study is to examine the effect of number of cigarillos per package on use behaviors, intensity of use and biomarkers of exposure.

  • 24 Mar, 2022
  • 1 location
BabySTEPs: Supportive Texts Empowering Parents

This R34 will develop a theory-driven, adaptive text messaging intervention (TMI) for risky drinking in postpartum women.

Accepts healthy volunteers
  • 04 Oct, 2022
Dialectical Behavior Therapy for Youth With Bipolar Disorder

Dialectical behavior therapy (DBT) will be conducted over 1 year in youth with bipolar disorder (BD). DBT will be divided into two modalities: 1) DBT skills training; and 2) DBT individual therapy sessions. Skills training sessions will incorporate the 5 standard adolescent DBT modules: mindfulness skills, emotion regulation skills, distress …

antimanic agents
  • 18 Dec, 2021
  • 1 location
Semaglutide in Comorbid Schizophrenia Spectrum Disorder and Obesity (Sema)

Rates of obesity in patients with schizophrenia-spectrum disorder (SSD)s have reached epidemic proportions, with established contributing effects of antipsychotic (AP) medications. Among agents approved for chronic weight management, glucagon-like peptide-1 receptor agonists (GLP-1RA) are associated with reductions in cardiovascular mortality, with recent FDA approval for once weekly semaglutide for this …

  • 08 Jul, 2022
  • 1 location
Use of a Smartphone Application (App) to Assist a Cognitive-Behavioral Smoking Cessation Treatment

This randomized controlled clinical trial examines the effectiveness of a face-to-face* cognitive-behavioral behavioral treatment to quit smoking enriched with an App. This project aims to innovate in the psychological smoking cessation treatment and increase abstinence rates in the short and long term. Due to the COVID-19 the face-to-face treatment will …

  • 04 Oct, 2021
  • 1 location