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Found 441 clinical trials
Middle School Cluster Randomized Controlled Trial (RCT) to Evaluate E-Cigarette Prevention Program: CATCH My Breath

This is a two-arm, cluster randomized trial designed to to evaluate the effectiveness of an e-cigarette curriculum [called the CATCH My Breath (CMB) program] in delaying the onset of e-cigarette use in middle schoolers. Schools will be assigned to either the CMB program or usual care, which is Texas Education …

Accepts healthy volunteers
  • 19 views
  • 06 Apr, 2022
  • 1 location
Evaluation of a Practice-oriented Recovery Program for Female Endurance Athletes With Relative Energy Deficiency

The aim of this study is to develop, implement and evaluate the effects of a 16 week practice orientated sports nutrition education and counselling program aiming to improve energy availability and to investigate the effects on physiological and psychological health, sports nutrition knowledge, and athletic performance in well-trained female endurance …

  • 0 views
  • 20 Jul, 2021
  • 4 locations
Evaluating Buprenorphine/Naloxone Microdosing vs. Standard Dosing in Emergency Departments

This is a multi-centre, open-label RCT at four Emergency Departments (EDs) in British Columbia and Alberta. The purpose of the current study is to compare the effectiveness of buprenorphine/naloxone microdosing and standard dosing take-home induction regimens at enabling patients to successfully complete the induction regimen, and at retaining patients on …

  • 14 views
  • 10 Aug, 2021
  • 4 locations
Metabolism Informed Smoking Treatment: The MIST RCT

This phase 3 randomized controlled trial will test Metabolism-Informed Smoking Treatment (MIST), a precision approach to smoking treatment that biologically tailors medication selection to nicotine metabolism.

  • 18 views
  • 04 Oct, 2022
  • 1 location
NIDA-CTN-0100: Optimizing Retention, Duration and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (RDD)

This is a two phase study investigating combinations of pharmacological and behavioral interventions to optimize the treatment of Opioid Use Disorder (OUD). The Retention Phase will assess strategies for improving retention on buprenorphine (BUP) and extended-release injectable naltrexone (XR-NTX). The Discontinuation Phase will assess which approaches are most likely to …

  • 76 views
  • 14 Oct, 2022
  • 18 locations
Repetitive dTMS Intervention for Methamphetamine Addiction

whether repeated dTMS intervention of medial prefrontal and cingulate cortices in methamphetamine addiction could reduce the subjective craving and improve the cognitive abilities.

  • 332 views
  • 10 Jul, 2022
  • 1 location
Mindfulness-Oriented Recovery Enhancement (MORE) in Heroin Addiction

addiction; clinical outcomes will be assessed before, immediately and three months after treatment. Results could point to factors that track and predict recovery with treatment, offering clinicians markers

  • 0 views
  • 25 Jan, 2021
  • 1 location
Effect of Menthol on ENDS Users' Addiction and Exposure

with tobacco flavors. The proposed studies will answer two key regulatory questions consistent with FDA's focus on the role of flavor in tobacco products' addiction and toxicity; 1) compared to tobacco

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Development of Neuroimaging Methods to Assess the Neurobiology of Addiction

Background Abusing alcohol, drugs, and other substances can cause serious health problems. These substances also can affect brain function. Researchers want to learn more about brain function by using magnetic resonance imaging (MRI). This uses a magnetic field and radio waves to take pictures of the brain. Objective To develop …

Accepts healthy volunteers
  • 572 views
  • 25 Oct, 2022
  • 1 location
Assessing the Effect of Nicotine Reduction on ENDS User's Addiction and Exposures

The rapid increase of electronic nicotine delivery systems (ENDS) use by young people in the US and their potential to harm health, cause addiction, and serve as a risk for cigarette smoking or

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location