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Found 4 clinical trials
Human Absorption, Distribution, Metabolism, and Excretion Study of [14C]Adavosertib (ADME)

This is a non-randomised study in patients with advanced solid malignancies

  • 0 views
  • 21 Jul, 2022
  • 1 location
A Study to Assess the Effects of Itraconazole, Rifampicin, and Omeprazole on Pharmacokinetics of Adavosertib

This is a Phase 1, open-label, non-randomised, 3-arm (A, B, and C), drug-drug interaction study in patients with advanced solid tumours.

  • 0 views
  • 15 Jul, 2022
  • 4 locations
Adavosertib With or Without Olaparib in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

This phase II trial studies how well adavosertib with or without olaparib work in treating patients with ovarian, primary peritoneal, or fallopian tube cancer that has come back (recurrent

cancer
neutrophil count
direct bilirubin
serum pregnancy test
measurable disease
  • 8 views
  • 20 Jul, 2022
  • 2 locations
Adavosertib Before Surgery in Treating Patients With Advanced High Grade Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

This pilot early phase I trial studies how adavosertib affects the tumor deoxyribonucleic acid (DNA) of patients undergoing surgery for high grade (fast growing or aggressive) ovarian, fallopian

absolute neutrophil count
neutrophil count
primary peritoneal carcinoma
levonorgestrel
carcinomatosis
  • 18 views
  • 15 May, 2022
  • 8 locations