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Found 406 clinical trials
Study Assessing the Efficacy of Etoricoxib in Female Patients With Fibromyalgia

The main of the proposed study is to assess whether the use of the Cox-2 inhibitor Etoricoxib is beneficial for the use in fibromyalgia. We intend to seek whether this medication may improve psychiatric and rheumatologic parameters of the disease.

  • 267 views
  • 07 Nov, 2020
  • 1 location
Neuraxial Pethidine After Lumbar Surgery Trial

The hypothesis is that epidural pethidine is an effective form of pain relief following lumbar spinal surgery, resulting in significantly lower usage of concomitantly administered (intravenous) patient-controlled analgesia (PCA) pethidine.

analgesia
pain relief
  • 55 views
  • 07 Nov, 2020
  • 1 location
Dosing of Ketorolac in the Emergency Department

The optimal dose of ketorolac in the Emergency Department setting is no clear. We will compare 3 doses to determine the optimal dose.

ketorolac
  • 16 views
  • 26 Jan, 2021
  • 1 location
Intravenous Acetaminophen and Morphine Versus Intravenous Morphine Alone for Acute Pain in the Emergency Department

In emergency medicine, acute pain is a common reason for consultation. It is recommended that patients in moderate to severe pain should receive a combination of intravenous acetaminophen and

morphine
  • 1 views
  • 16 May, 2021
  • 11 locations
Spinal Manipulation and Patient Self-Management for Preventing Acute to Chronic Back Pain

The long-term objective is to reduce overall low back pain (LBP) burden by testing scalable, first-line, non-pharmacologic strategies that address the biopsychosocial aspects of acute/sub-acute LBP and prevent transition to chronic back pain. The US is in the midst of an unprecedented pain management crisis. LBP is the most common …

analgesics
opioid
manipulative therapy
back pain
analgesia
  • 403 views
  • 29 Apr, 2021
  • 3 locations
Comparison of Two Schedules of Zoledronic Acid in Treating Patients With Breast Cancer That Has Spread to the Bone

RATIONALE: Zoledronic acid may help decrease the risk of broken bones, bone pain, and other symptoms caused by bone metastases. It may also help patients live more comfortably. PURPOSE: This randomized clinical trial is studying different schedules of zoledronic acid to compare how well they work in treating patients with …

combination therapy
bone metastases
bisphosphonate
cancer
zoledronic acid
  • 124 views
  • 07 Nov, 2020
  • 1 location
Efficacy and Safety of Tolperisone in Subjects With Pain Due to Acute Back Muscle Spasm

This is a double-blind, randomized, placebo-controlled, multicenter study of the efficacy and safety of tolperisone (a non-opioid) or placebo administered in subjects with pain due to acute back muscle spasm.

opioid
body mass index
muscle spasm
back pain
massage
  • 35 views
  • 05 Sep, 2021
  • 76 locations
Effect of Combinations of Paracetamol Ibuprofen and Dexamethasone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty

Multimodal pain management is essential for recovery after surgery, aiming to target different pain mechanisms to minimize opioid usage and opioid-related adverse effects. Evidence for benefits and harms of various non-opioid analgesic combinations is, however, nearly non-existing, and large-scale trials are urgently needed. Recently, the investigators have demonstrated that combining …

glucocorticoids
opioid
ibuprofen
analgesic
hip arthroplasty
  • 0 views
  • 26 Jan, 2021
  • 9 locations
Paracetamol / Ibuprofen for Postpartum Pain in the Early Postpartum Period

The investigators will examine the effectiveness of non-opioid analgesia (Paracetamol versus Ibuprofen) in the early postpartum period

  • 0 views
  • 27 Jan, 2021
  • 1 location
Perioperative Lidocaine or Epidural Anesthesia on Outcomes in Complex Spine Surgery

The primary goal is to assess whether Lidocaine/IVPCA is better in morphine requirements and simultaneously not worse in pain control measured by VAS pain score compared to IVPCA alone.

anesthesia
morphine
lidocaine
propofol
  • 21 views
  • 07 Nov, 2020
  • 1 location