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Found 87 clinical trials
Adrecizumab Dose Escalation Safety and Tolerability Evaluation (ADESTE)

for HAM8101 (Adrecizumab) in AHF, using a dose escalating design. Acute Heart Failure (AHF), both as deterioration of chronic stable condition or "de novo" onset constitutes a major indication

  • 5 views
  • 17 Mar, 2021
  • 2 locations
Treatment With the Ketone Body 3-hydroxybutyrate in Patients With Cardiogenic Shock

Background Cardiogenic shock is a life-threatening state of acute heart failure with severely depressed blood pressure and organ perfusion. The 30-day mortality is reported as high as 50%. To

  • 0 views
  • 27 Jan, 2021
  • 1 location
Study on Early Intra-aortic Balloon Pump Placement in Acute Decompensated Heart Failure Complicated by Cardiogenic Shock

The aim of the study is to demonstrate the superiority of early intra-aortic balloon pump implantation at admission over local clinical practice (pharmacological only) in acute decompensated heart failure patients with cardiogenic shock, with respect to 60-day survival or successful bridge to heart replacement therapies (heart transplant or Left Ventricular …

oliguria
hypoperfusion
heart transplantation
heart failure
ejection fraction
  • 0 views
  • 22 Aug, 2021
  • 1 location
External Counterpulsation Therapy for Severe Steno-occlusive Intracranial Stenosis

Intracranial stenosis is prevalent among Asians and constitute a common cause of cerebral ischemia. While the best medical therapy carries stroke recurrence rates in access of 10% per year, intracranial stenting was associated with unacceptable peri-procedural ischemic events. Cerebral ischemic events are strongly related to the severity of intracranial stenosis, …

stenosis
ischemia
acute stroke
cerebral infarction
stroke
  • 12 views
  • 22 Jan, 2021
  • 1 location
Therapeutic Education Strategy for Patients With Acute Heart Failure

The EduStra-HF study will examine the impact of an intensive therapeutic education on patients discharged from hospital after an episode of acute heart failure (HF). Patients will be

acute heart failure
  • 78 views
  • 19 Mar, 2021
  • 7 locations
Optimize Heart Failure Care During TRANSitional Period in Patients With Acute Heart Failure.

The period of about a month after the discharge of acute heart failure patients is defined as a transition time. During this period, the patient has a high mortality rate and a readmission rate

  • 0 views
  • 30 May, 2021
  • 1 location
Early or Non-revoked in Hospital-day in Patients With Acute Heart Failure

Heart failure is one of the major causes of hospitalization in Brazil and worldwide. Recent studies attempt to identify readmission and prognostic markers at the time of discharge from these patients. The reassessment and possibility of early therapeutic adjustment may be relevant in this context. Therefore, the prospective and randomized …

chest x-ray
edema
dyspnea
pulmonary congestion
ascites
  • 0 views
  • 22 Jan, 2021
  • 2 locations
Dapagliflozin and Effect on Cardiovascular Events in Acute Heart Failure -Thrombolysis in Myocardial Infarction 68 (DAPA ACT HF-TIMI 68)

fraction [LVEF] 40%) who have been stabilized during hospitalization for acute heart failure, evaluating the effect of in-hospital initiation of dapagliflozin versus placebo on the clinical outcome of

ejection fraction
dyspnea
b-type natriuretic peptide
diagnostic tests
nt-probnp
  • 0 views
  • 20 May, 2021
Discharge Planning in Emergency Department for Frail Older With AHF

acute heart failure (AHF) discharged from Emergency Departments (EDs) and to validate the results of MGDP in real life. Method: Investigators will select frail patients 70 years with primary

heart failure
  • 0 views
  • 22 Jan, 2021
Medico-economic Evaluation of Therapeutic Adaptation Guided by the Soluble Suppression of Tumorigenicity 2 (sST-2) Biomarker in the Management of Patients With Acute Heart Failure

Management of patients with heart Failure remains a major health concern because of the high rate of rehospitalization, mortality and induced-cost. Biomarkers could help to guide the management of patients with heart failure (HF). Soluble suppression of tumorigenicity 2 (sST2) appears as a promising biomarker. As a working hypothesis, we …

  • 0 views
  • 14 May, 2021
  • 2 locations