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Found 450 clinical trials
Phase I Clinical Trial to Determine the Safety of Clonidine in Infants With HIE During Therapeutic Hypothermia.

Hypoxic ischemic encephalopathy (HIE) occurs in ~ 2-4/1000 term infants and is a major cause of neonatal morbidity and mortality. To date, therapeutic hypothermia started within 6 h of birth is the only intervention known to be effective in reducing the morbidity and mortality of HIE. Hypothermia does not totally …

  • 14 views
  • 08 Nov, 2020
  • 1 location
  • 0 views
  • 06 Apr, 2022
  • 1 location
  • 0 views
  • 14 Jul, 2022
  • 1 location
Hypersensitivity to Opening of BKCa Channels in Post-Traumatic Headache

headache (PTH) attributed to mild traumatic brain injury (mTBI).

  • 0 views
  • 07 Oct, 2022
  • 1 location
Brain Activity During Bladder Filling: Pilot Study of an fMRI Protocol

bladder function may be related to the presence of incontinence. The current pilot study is the first study of a research project focusing on correlations between brain damage and incontinence

Accepts healthy volunteers
  • 0 views
  • 13 Mar, 2022
  • 1 location
Prazosin for the Prophylaxis of Chronic Post-Traumatic Headaches in OEF/OIF/OND Service Members and Veterans With Mild TBI

Mild traumatic brain injury (mTBI) caused by blast effects of explosive devices has been called the "signature injury" of soldiers who served in the Iraq and Afghanistan conflicts. mTBI can also

  • 73 views
  • 16 Oct, 2022
  • 2 locations
Multidisciplinary Translational Approach to Investigate Mechanisms Predictors & Prevention of Persistent PTH

brain injury, and identify methods of preventing post-traumatic headache persistence. The objective of the clinical trial component of the Focused Program is to determine whether intervention

  • 0 views
  • 18 Feb, 2021
  • 3 locations
Imaging of Neuro-Inflammation and the Risk for Post-Traumatic Epilepsy

This study plans to evaluate the time course of inflammation in the brain after a moderate to severe traumatic brain injury using positron emission tomography (PET) brain imaging. Patients will

  • 5 views
  • 04 Oct, 2022
  • 1 location
Identifying Correlates of Brain Microglial Activation in Neuropsychiatric Syndromes: A Dimensional Approach

, chronic pain syndrome, dementia, traumatic brain injury, or substance abuse. The research will also explore whether there is more inflammation in patients with more neuropsychiatric symptoms. Inflammation

Accepts healthy volunteers
  • 206 views
  • 15 Feb, 2022
  • 1 location
Effects of Remote Ischemic Conditioning on Bimanual Skill Learning and Corticospinal Excitability in Children With Unilateral Cerebral Palsy (RIC)

Unilateral cerebral palsy (UCP) is a leading cause of childhood disability. An early brain injury impairs the upper extremity function, bimanual coordination, and impacts the child's

  • 0 views
  • 04 Apr, 2023
  • 1 location