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Found 358 clinical trials
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The Axcelsius Study: A Study of ONO-7475 in Patients with Acute Leukemias

What is the Axcelsius study? The Axcelsius study is a clinical research study being conducted to determine the safety and tolerability of the study drug called ONO-7475. ONO-7475 has been tested in AML patients and was confirmed safe and tolerable at a dose to be used in the study. Previous …

refractory acute myeloid leukemia (aml)
acute leukemia
remission
blast cells
cancer
  • 0 views
  • 23 Jul, 2021
  • 3 locations
Multi-centre Prospective Cohort of Childhood Leukaemia: Determinants of Health and Quality of Life of the Patients After Treatment for an Acute Leukaemia During Childhood or Adolescence - LEA

Regular advances in cancer treatment have dramatically improved the prognosis of children and adolescents with acute leukemia (AL), raising with a great acuity the problem of the late physical

  • 0 views
  • 21 Jan, 2021
  • 1 location
CD19/CD22-Dual-STAR-T for Patients With B Cell Acute Leukemia(B-ALL)

This is a single center, single arm, open-lable phase I study to determine the safety and efficacy of CD19/CD22-Dual-STAR-T cells in patients with refractory and relapsed B cell acute leukemia

  • 0 views
  • 14 Jun, 2021
  • 1 location
Intermittent Liposomal Amphotericin B Primary Prophylaxis

The purpose of this trial is to see which dose of liposomal amphotericin B is the safest when used as a preventer against invasive fungal infection in patients with acute leukaemia who

acute leukemia
  • 16 views
  • 07 Nov, 2020
  • 1 location
Microcirculation in Patients With Leukemic Hyperleukocytosis

Hyperleukocytosis in patients with acute leukemia impacts rheology and microvascularization, leading to severe symptoms or even death. The investigators investigated whether blood stream

  • 0 views
  • 24 Jan, 2021
  • 1 location
Risk Stratification-directed NAC for Prevention of Poor Hematopoietic Reconstitution

incidence of poor hematopoietic reconstitution after allo-HSCT in patients with ECs <0.1% pre-HSCT. Therefore, the investigators designed the study with acute leukemia patients who will be

cell transplantation
acute leukemia
n-acetylcysteine
remission
  • 0 views
  • 26 Jan, 2021
  • 1 location
The Role of Ruxolitinib in Secondary Acute Myelogenous Leukemia Evolving From Myeloproliferative Neoplasm

This trial aimed to investigate the therapeutic efficacy of ruxolitinib in combination with cytotoxic chemotherapy for post-myeloproliferative neoplasm secondary acute myeloid leukemia.

  • 1 views
  • 24 Jan, 2021
  • 2 locations
Different Therapies in Treating Infants With Newly Diagnosed Acute Leukemia

from happening. It is not yet known which treatment regimen is most effective in treating acute leukemia. PURPOSE: This randomized clinical trial is studying how well different therapies work in

mercaptopurine
cyclophosphamide
white blood cell count
pegaspargase
bone marrow transplant
  • 12 views
  • 23 Jan, 2021
  • 5 locations
A Study of JNJ-75276617 in Participants With Acute Leukemia

The purpose of this study is to determine the recommended Phase 2 dose(s) (RP2D[s]) of JNJ-75276617 in Part 1 (Dose Escalation) and to determine safety and tolerability at the RP2D(s) in Part 2 (Dose Expansion).

acute leukemia
hydroxyurea
gilbert's syndrome
serum bilirubin level
direct bilirubin
  • 0 views
  • 01 Aug, 2021
  • 27 locations
Matched Unrelated vs. Haploidentical Donor for Allogeneic Stem Cell Transplantation in Patients With Acute Leukemia

Primary objective of this open label, two-arm, multicenter, multinational, randomized trial is to compare anti-leukemic activity of allogeneic stem cell transplantation for patients with acute

acute leukemia
cyclophosphamide
remission
cell transplantation
leukemia
  • 1 views
  • 03 May, 2021
  • 24 locations