Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 13 clinical trials
Clinical Trial of Quadrivalent Recombinant Norovirus Vaccine (Pichia Pastoris)

The purpose of the research is to evaluate the safety and tolerability of the tetravalent recombinant Norovirus vaccine at different doses, to initially explore the immunogenicity of the vaccine, and to determine the appropriate dose of the product for later clinical trials.This trial adopts the seamless design of phase I/IIa, …

Accepts healthy volunteers
  • 17 views
  • 07 Oct, 2022
  • 1 location
A Phase 2b Double-Blinded, Randomized, Placebo-Controlled, Human Norovirus GI.1 (Norwalk Virus Inoculum) Challenge Study Following Administration of an Oral, Single-dose Norovirus Vaccine Expressing GI.1 VP1 and dsRNA Adjuvant to Protect Against Norovirus Gastroenteritis (NVG) in Healthy Adult Volunteers (G1-1 Challenge)

. After challenge, subjects will be monitored for signs and symptoms of acute gastroenteritis (AGE) from Day 29 to discharge. At 4 days post challenge (Day 33) asymptomatic subjects will be discharged

Accepts healthy volunteers
  • 0 views
  • 17 Oct, 2022
  • 1 location
Phase I Study to Determine the Optimal Human Challenge Dose for Norovirus GII.4 CIN-3 Batch No.: 01-16C3

This is a safety and infectivity study of experimental human Norovirus genogroup GII.4 administered to 48 healthy non-pregnant adults, 18-49 years of age, negative for COVID-19 by antigen testing at the time of norovirus challenge. Subjects will be admitted to the Vaccine Research Center inpatient facility and challenged with a …

Accepts healthy volunteers
  • 0 views
  • 25 Oct, 2022
  • 1 location
Multi-DOSE Oral Ondansetron for Pediatric Acute GastroEnteritis (DOSE-AGE)

A phase III, double-blind, parallel-design, randomized, placebo controlled trial to compare multi-dose oral Ondansetron with placebo as treatment for vomiting secondary to acute gastroenteritis

ondansetron
ondansetron oral
gastroenteritis
vomiting
acute gastroenteritis
  • 18 views
  • 20 Feb, 2022
  • 4 locations
A Phase 2b, Double-blind, Randomized, Multi-site, Placebo-controlled Trial to Evaluate the Efficacy, Safety and Immunogenicity of Intramuscular HIL-214 Norovirus Vaccine in Healthy Children 5 Months of Age at Initial Vaccination

This is a randomized, placebo-controlled study that is being done to evaluate the safety and effectiveness of two doses of the HIL-214 vaccine compared to a placebo. The study will enroll 3000 children who will be 5 months of age at the time of the first dose study vaccine. The …

Accepts healthy volunteers
  • 0 views
  • 21 Oct, 2022
  • 9 locations
The Follow-up Automatically vs. As-Needed Comparison Trial (FAAN-C)

Compare the effectiveness of automatic vs as-needed (PRN) post-hospitalization follow-up for children who are hospitalized for common infections.

pneumonia
acute gastroenteritis
  • 0 views
  • 27 Oct, 2022
  • 5 locations
Sucrose at Triage for Acute Gastroenteritis Episode in Children (STAGE)

Background: Acute viral gastroenteritis is a very common pediatric medical condition that results in a large number of emergency department (ED) visits. Fasting-induced ketosis has been suggested to contribute to nausea and vomiting in children with VGE. To date, there is no data on the impact of oral sucrose intake …

ondansetron
fasting
acute gastroenteritis
nausea
  • 0 views
  • 27 May, 2022
  • 1 location
The Effectiveness of Pleuran in Treatment of Acute Gastroenteritis in Children (EPTAGE)

Acute gastroenteritis (AGE) is one of the most common causes of children's morbidity and mortality globally. Oral or intravenous rehydration is the only effective treatment in reducing morbidity

  • 20 views
  • 15 Mar, 2022
  • 1 location
Prevelane and Short Term Outcome of Hypernatremic Dehydration in Children With Acute Gastroenteritis in Sohag University Hospital

Hypernatremic dehydration (HND) is a common and potentially life-threatening condition in children. It is defined by a serum level of sodium greater than or equal to 145 mmol/L . HND is a type of acute dehydration constitutes a medical emergency and requires a rapid diagnosis for adequate and quick management. …

  • 0 views
  • 09 Jul, 2022
  • 1 location
Infectious Etiology of Vomiting in Children With Presumed Acute Gastroenteritis

In children with acute gastroenteritis (AGE), vomiting often precedes diarrhea. To establish the diagnosis of AGE, enteropathogen detection typically relies on diarrheal stool samples. However

diarrhea
acute gastroenteritis
  • 0 views
  • 14 Jul, 2022
  • 1 location