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Found 34 clinical trials
Impact of Hypertonic Saline Solution on Acute Decompensated Heart Failure (HSS)

Acute Decompensated Heart Failure (ADHF).However, chronic treatment with diuretics may limit their response and deteriorates the renal function. The hypertonic saline solution (HSS) has been proposed in

  • 18 Apr, 2022
  • 1 location
The STOP-ADHF Study: Stimulation of the Cardiopulmonary Nervous System in Acute Decompensated Heart Failure

STOP-ADHF Study: An evaluation of the safety and performance of the Cardionomic Cardiac Pulmonary Nerve Stimulation (CPNS) system in patients with acute decompensated heart failure.

  • 11 Oct, 2022
  • 14 locations
Low Level Tragus Stimulation in Acute Decompensated Heart Failure (TREAT-HF)

Acute Decompensated Heart Failure (ADHF) is a major cause of morbidity and mortality. It is associated with increased systemic inflammation. Previous studies have demonstrated increased levels

vagal stimulation
acute heart failure
  • 23 Feb, 2022
  • 1 location
Cardiac Pulmonary Nerve STIMulation in Acute Decompensated Heart Failure

The STIM-ADHF Study is a multi-center, observational study to assess the performance and safety of the CPNS System in patients with ADHF.

  • 13 Oct, 2022
  • 3 locations
Study on Early Intra-aortic Balloon Pump Placement in Acute Decompensated Heart Failure Complicated by Cardiogenic Shock (Altshock-2)

The aim of the study is to demonstrate the superiority of early intra-aortic balloon pump implantation at admission over local clinical practice (pharmacological only) in acute decompensated

heart failure
intraaortic balloon pumping
ejection fraction
fluid overload
  • 22 Mar, 2022
  • 1 location
Interest of Levosimendan in Reducing Weaning Failures of ExtraCorporeal Life Support - ECLS

Extracorporeal life support (ECLS) is a circulatory cardio supplementation technique; it therefore makes it possible to compensate for a defective cardiac or cardio-respiratory function. ECLS nevertheless remains a temporary assistance technique pending a potential recovery of cardiac function, or it can be used to direct patients towards a heart transplant …

extracorporeal life support
chronic heart failure
  • 09 May, 2021
  • 1 location
Evaluation of Blood Volume Analysis- Guided Management of Decompensated Heart Failure

Diuretic therapy is first-line treatment for acute decompensated heart failure. However, accurate assessment and management of patient blood volume is challenged by the limitations of physical

  • 04 Oct, 2022
  • 1 location
DORAYA-HF Early Feasibility Study

The study objective is to evaluate the feasibility of the Doraya Catheter and measure clinical performance and safety endpoints, in ADHF patients deemed to have insufficient diuretic response

  • 04 Oct, 2022
  • 5 locations
Splanchnic Nerve Block for Therapy of Chronic Heart Failure (Splanchnic III)

Splanchnic vasoconstriction may contribute to decompensation of chronic heart failure (HF) via volume redistribution from the splanchnic vascular bed to the central compartment. This is a sympathetically mediated reflex and can be interrupted through a splanchnic nerve block (SNB). We hypothesize that interruption of the efferent/afferent innervation of the splanchnic …

  • 30 Nov, 2021
  • 1 location
Biomarker Guided Discharge of Heart Failure Patients (RADAR)

This is a multi-centre, single blind, randomized study. Patients admitted to hospital with acute decompensated heart failure will be randomized to biomarker guided discharge algorithm vs usual

  • 13 Jun, 2022
  • 1 location