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Found 250 clinical trials
Study to Evaluate the Efficacy and Safety of MAS825 in NLRC4-GOF Patients (MAS NLRC4-GOF)

This study is a Phase 2 trial designed to evaluate the clinical efficacy, safety, and tolerability of MAS825 in patients with NLRC4-GOF

  • 0 views
  • 23 May, 2022
  • 8 locations
MyopiaX Treatment for the Reduction of Myopia Progression in Children and Adolescents: Safety and Efficacy Investigation (MyopiaX-1)

The purpose of this trial is to investigate the safety and efficacy of MyopiaX - a digital treatment intended to slow the progression of myopia in children and adolescent.

  • 0 views
  • 25 Mar, 2022
  • 3 locations
Pediatric Arthritis Study of Certolizumab Pegol (PASCAL)

A Multicenter, Open-label Study to Assess the Pharmacokinetics, Safety and Efficacy of Certolizumab Pegol in Children and Adolescents With Moderately to Severely Active Polyarticular-course Juvenile Idiopathic Arthritis (JIA).

  • 30 views
  • 03 Jun, 2022
iFR Guided Multi-vessel Revascularization During Percutaneous Coronary Intervention for Acute Myocardial Infarction

In patients with acute ST-elevation myocardial infarction (STEMI), 40-60% have multi-vessel disease with an increased cardiovascular morbidity and mortality. Although it is not recommended to revascularize noninfarct lesions during the acute intervention, recent investigations suggest the opposite and show improved outcome after direct revascularization of noninfarct lesions. It is undesirable …

stenosis
percutaneous coronary intervention
stemi
  • 0 views
  • 16 Dec, 2021
  • 1 location
STOP-MSU: Stopping Haemorrhage With Tranexamic Acid for Hyperacute Onset Presentation Including Mobile Stroke Units

The study is a prospective phase II randomised, double-blind, placebo-controlled investigator-driven trial in acute intracerebral haemorrhage patients. The study has 2 arms with 1:1 randomisation to either intravenous tranexamic acid or placebo and will test the hypothesis that in patients with spontaneous ICH, treatment with tranexamic acid within 2 hours …

hematoma
intracranial hemorrhage
stroke
  • 25 views
  • 20 Apr, 2022
  • 24 locations
Open Label Randomized Multicenter to Assess Efficacy & Tolerability of Ofatumumab 20mg vs. First Line DMT in RMS (STHENOS)

This study will compare ofatumumab vs. European approved platform first line self-administered disease modifying therapy (DMT) in newly diagnosed MS patients

teriflunomide
dimethyl fumarate
MRI
glatiramer acetate
interferon
  • 0 views
  • 09 May, 2022
  • 34 locations
Eptinezumab as Preventive Treatment of Migraine in Adults With Migraine (Sunrise)

This study evaluates the efficacy of eptinezumab to prevent migraine in patients with chronic migraine

headache
  • 0 views
  • 24 May, 2022
  • 52 locations
Effect of PACK Health Support Program on Patient Reported Outcomes in Patients With Breast Cancer

This trial studies the effect of an electronic health (eHealth) support program called PACK Health on patient reported health outcomes in patients with breast cancer. PACK Health monitors breast cancer patients' reported side effects and experience of care when receiving chemotherapy. Participating in the PACK Health coaching program may improve …

invasive breast cancer
carcinoma
carcinoma in situ
ductal carcinoma
cancer
  • 4 views
  • 14 Feb, 2022
  • 1 location
A Study to Evaluate Safety and Efficacy of APO-2 at Three Different Doses in Patients With Diabetic Foot Ulcer

The MARSYAS II study which will be conducted in patients with diabetic foot ulcer (DFU) consists of a Lead-In Phase for safety assessment of multiple doses of the biologic investigational medicinal product (IMP) APO-2 and of a Main Phase (Phase II Study) to assess the efficacy and safety of the …

hemoglobin a1c
foot ulcer
diabetes
  • 0 views
  • 23 Apr, 2022
  • 6 locations
Effectiveness of a Smoking Cessation Algorithm Integrated Into HIV Primary Care

To determine the efficacy of an algorithm designed to recommend smoking cessation-related pharmacotherapy options to the primary care providers of smokers living with HIV/AIDS.

nicotine patch
nicotine replacement
smoking cessation
AIDS
varenicline
  • 0 views
  • 12 Sep, 2021
  • 1 location