Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 310 clinical trials
Granulocyte-Macrophage Stimulating Factor (GM-CSF) in Peripheral Arterial Disease

Peripheral artery disease (PAD) is a disease in which plaque builds up in the arteries that carry blood to the head, organs, and limbs. PAD usually occurs in the arteries in the legs, but can affect any arteries. Over time, plaque can harden and narrow the arteries which limits the …

  • 167 views
  • 28 Oct, 2021
  • 1 location
Effect of Testosterone Treatment on Embryo Quality

The purpose of this study is to determine the effect of treatment with trans-dermal testosterone cream compared to placebo on measures of ovarian reserve, oocyte and embryo quality, and pregnancy rates among women with evidence of diminished ovarian reserve that have persistently low serum testosterone and free testosterone after completing …

diminished ovarian reserve
dehydroepiandrosterone
follicle stimulating hormone
dhea
  • 540 views
  • 26 Jan, 2021
  • 2 locations
MMV533 Plasmodium Falciparum Volunteer Infection Study

A Phase 1b study to assess the safety, tolerability and antimalarial activity of MMV533 against Plasmodium falciparum 3D7 blood stage infection in healthy volunteers

Accepts healthy volunteers
  • 4 views
  • 08 Aug, 2022
  • 1 location
The Soy Treatment Evaluation in Metabolic Syndrome (STEM) Trial

Strategies to reduce sugar-sweetened beverages (SSB) have become one of the leading public health targets to address the epidemics of obesity and diabetes. National food, nutrition, and health policies and programs have positioned low-fat milk as the preferred caloric replacement strategy for SSBs. This strategy derives from evidence that replacement …

diabetes
fasting plasma glucose
metabolic syndrome
fasting
plasma glucose
  • 0 views
  • 24 Mar, 2022
Ambroxol in New and Early DLB, A Phase IIa Multicentre Randomized Controlled Double Blind Clinical Trial (ANeED)

This is a confirmatory investigational medicinal product (IMP) study to investigate the effects on cognition, functional decline and on neuropsychiatric symptoms of the Glucocerebrosidase (GCase) enhancing chaperone ambroxol in participants diagnosed with prodromal and early dementia with Lewybodies (DLB).

dementia
cognitive impairment
follicle stimulating hormone
mild cognitive impairment
mini-mental state examination
  • 0 views
  • 25 Jan, 2022
  • 1 location
Understanding Trauma Nightmares Using In-Home Measurement

Trauma-related nightmares in Veterans are associated with poor clinical outcomes, greater substance use, and increased risk of suicide. In spite of an urgent need to reduce the burden of trauma-related nightmares, the underlying physiological changes associated with them are poorly understood, and there are no clear evidence-based recommendations for their …

nightmares
substance use
  • 96 views
  • 21 Mar, 2022
  • 1 location
Viral Infection in Asthma (VIA) Study (VIA)

Often when people with asthma get a virus caused by the common cold (rhinovirus), they also experience an increase or worsening of their asthma symptoms. The purpose of this study is to see if the study medication dupilumab helps prevent those with mild to moderate asthma from having increased asthma …

  • 0 views
  • 05 Jun, 2022
  • 1 location
Sleep in Psychiatric Care (SIP): Treatment for Comorbid Delayed Sleep-Wake Phase Disorder (DSWPD) (SIP)

Sleep disorders commonly co-occur with psychiatric disorders. Sleep disorders are often treated with medication or not at all in psychiatric care, although there exist a plethora of documentation of the effectiveness of sleep interventions. There is also an increase in studies showing effectiveness of sleep-interventions when the sleep disorder co-occurs …

melatonin
delayed sleep phase syndrome
  • 0 views
  • 09 Jun, 2022
  • 1 location
TReatment for ImmUne Mediated PathopHysiology (TRIUMPH)

TReatment for ImmUne Mediated PathopHysiology (TRIUMPH) is a multi-center, three arm, randomized, controlled trial of immunosuppressive therapy for children with acute liver failure. The study will determine if suppressing inflammatory responses with either corticosteroids or equine anti-thymocyte globulin therapy improves survival for children with this rare, life-threatening condition.

mediators
encephalopathy
liver injury
corticosteroids
  • 0 views
  • 29 Jul, 2022
  • 11 locations
The Intracerebral Hemorrhage Acutely Decreasing Arterial Pressure Trial II (ICH-ADAPT II)

The vast majority of intracerebral hemorrhage (ICH) patients present with elevated blood pressure(BP). Management of BP is controversial with two competing rationales. There is some evidence that hyperacute treatment may improve outcomes by reducing the rate of hematoma expansion. Physicians have been reluctant to reduce BP early after ICH onset, …

hematoma
ct scan
intracranial hemorrhage
ischemia
mediators
  • 14 views
  • 04 May, 2022
  • 2 locations