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Found 81 clinical trials
Characteristics and Outcomes of Patients With COVID-19 Treated With High-flow Nasal Oxygen and Awake-prone Position (AW-PP_Covid)

A subset of patients with COVID-19 develops acute respiratory failure and acute respiratory distress syndrome (ARDS) (1). The use of invasive mechanical ventilation for the treatment of these conditions is associated with high mortality rates (2,3). The use of high-flow nasal oxygen therapy (HFNO) and awake prone position (AW-PP) could …

oximetry
assisted ventilation
acute respiratory failure
covid-19
pao2
  • 0 views
  • 25 Mar, 2022
  • 1 location
Value of Fetal Scalp Lactate Sampling During Labour in Cases of Abnormal Fetal Heart Rate

ST-analysis of the foetal ECG (STAN®) is another second line technique for intrapartum foetal monitoring. Combining ST-analysis with standard CTG interpretation aims to identify hypoxic foetuses more accurately than CTG alone. The STAN® method identifies changes in the ST-interval of the foetal ECG that occur in the presence of foetalcentral …

  • 0 views
  • 13 Mar, 2022
  • 1 location
The Effect of Different Ketone Supplements on Blood β-OHB and Blood Glucose in Healthy Individuals

Ketone bodies are a fuel source and signaling molecule that are produced by your body during prolonged fasting or if you consistently eat at low-carbohydrate diet. Blood ketones can be used as a source of energy during fasting and are used by your brain as an alternative source of fuel …

Accepts healthy volunteers
  • 0 views
  • 13 May, 2022
  • 1 location
The Effects of Acute Ketone Monoester Supplementation on 20-Minute Time-Trial Performance in Trained Cyclists

Diet can alter blood ketone levels and this in turn may affect exercise capacity. This study will determine if the acute ingestion of a ketone supplement alters cycling time trial performance. Participants will perform two trials in a randomized order. Each trial will involve a 20-minute bout of cycling on …

Accepts healthy volunteers
  • 0 views
  • 23 Mar, 2022
  • 1 location
MI-CBT Adherence Program for Lifestyle Interventions in Older Adults (MI-CBT KNAP)

Objective 1: Assess feasibility and acceptability of all protocol components of a pilot pragmatic trial testing a 6-week telehealth ketogenic nutrition adherence (KNA) program using motivational interviewing and cognitive behavioral strategies (MI-CBT) compared to a KN information only group for older adults with mild cognitive impairment (MCI) in a community …

Accepts healthy volunteers
  • 0 views
  • 25 Jan, 2022
  • 1 location
Two Bag System for Diabetic Ketoacidosis (2BagDKA)

This is a study investigating the best way to treat diabetic ketoacidosis (DKA) with intravenous (IV) fluids in the hospital. The purpose of this study is to determine whether the "two bag" system of administering IV fluids for the treatment of adults with DKA leads to a shorter time requiring …

diabetic ketoacidosis
insulin
sugars
  • 4 views
  • 14 Feb, 2022
  • 1 location
Use of Blood Ketone Meters to Improve Ambulance Hyperglycaemia Care

In this KARMA2 feasibility study the investigators are testing whether ambulance staff can reliably and safely identify patients at high risk of diabetic ketoacidosis using blood ketone meters and start fluid (saline) therapy before arriving at hospital. The investigators aim to include 800 patients in this stepped wedge control study …

diabetic ketoacidosis
Accepts healthy volunteers
  • 0 views
  • 06 Nov, 2021
  • 1 location
StatStrip Glucose/Ketone Meter System Ketone Evaluation

The Nova StatStrip Glucose / Ketone Meter System is a fast, simple, whole blood system that can be used to quantify both glucose and ketones using two distinct test strips. This Protocol will describe an evaluation of the system's Ketone performance only. Ketone testing methods that quantify beta-hydroxybutyrate (-OHB), the …

hyperglycemia
Accepts healthy volunteers
  • 0 views
  • 19 Nov, 2021
  • 3 locations
Metabolic Effects of Exogenous 3-hydroxybutyrate in Patients With Type 1 Diabetes and Healthy Controls

The main objective of this clinical trial is to study the metabolic effects of intravenous infusion of the ketone body, 3-hydroxybutyrate (3-OHB), in patients with type 1 diabetes and healthy control subjects. Moreover, the investigators plan to examine regulatory mechanisms of 3-OHB that may be related to diabetic ketoacidosis. The …

diabetic ketoacidosis
diabetes
Accepts healthy volunteers
  • 0 views
  • 19 Dec, 2021
  • 1 location
Time-Restricted Feeding (TRIO)

We propose to conduct a randomized 6-day isocaloric crossover feeding study in humans with prediabetes and obesity. We will study the effect of restricting the timing of caloric intake to earlier in the day (TRF) versus later in the day (usual feeding pattern, UFP) on glycemia and inflammation in an …

Accepts healthy volunteers
fasting
hemoglobin a1c
  • 56 views
  • 29 Jun, 2022
  • 1 location