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Found 341 clinical trials
Onabotulinumtoxin A and Hyaluronic Acid Fillers in the Treatment of Facial Paralysis

Social interaction via facial mimic expression is crucial in human relationship and communication. Neural function disorder in this mechanism therefore affects human communication and social interaction. Facial nerve palsy is the paralysis of any structure innervated by the facial nerve, thus inibiting and severely compromising facial expression. In the last …

  • 0 views
  • 30 May, 2022
  • 1 location
The Effects of Tranexamic Acid or Placebo on Perioperative Bleeding in Adults Undergoing Liver Transplantation.

Around 230 million major procedures are performed worldwide each year. Postoperative complications after major surgery, especially in solid organ transplants, are associated with a significant increase in costs and mortality. Major bleeding episodes in major surgeries such as liver transplantation are related to a significant impact on morbidity and mortality. …

venous thromboembolism
stroke
clot
tranexamic acid
surgical blood loss
  • 0 views
  • 02 Sep, 2021
  • 1 location
Soluble Hyaluronic Acid Microneedle VS. Non-ablative Fractional Laser on Infraorbital Wrinkles.

This study is a prospective half-face controlled study, aiming to evaluate the therapeutic effects and adverse reactions of soluble hyaluronic acid microneedle and non-ablative fractional laser on infraorbital wrinkles and compare them.

Accepts healthy volunteers
  • 0 views
  • 05 Jul, 2022
  • 1 location
Ursodeoxycholic Acid in C. Difficile Infection

The primary objective of the study is to assess tolerability and adherence to treatment with ursodeoxycholic acid

  • 0 views
  • 07 Oct, 2022
  • 1 location
Efficacy and Safety of Obeticholic Acid in the Treatment of Primary Biliary Cholangitis

Obecholic acid is a modified bile acid and Farnesoid X receptor (FXR) agonist. FXR is a key regulator of bile acid synthesis and transport. Bile acids are used by the body to help with digestion. Conventional therapy with obecholic acid will improve liver function of patients with (primary biliary cholangitis)PBC. …

  • 0 views
  • 04 Oct, 2022
  • 1 location
Tranexamic Acid to Prevent OpeRation in Chronic Subdural Hematoma (TORCH)

Rationale: Chronic subdural hematoma (cSDH) is a frequently occurring disease, occurring mainly in the elderly. Surgical evacuation is effective, but also associated with life-threatening risks. In these old, often frail, patients with multi-comorbidity, surgery also comes with significant risks for future cognitive functioning and therefore, loss of independency. In five …

  • 18 views
  • 25 Mar, 2022
  • 1 location
Sulphur Amino Acid Requirements in Adults >60 Years

This study aims to determine the requirements for the sulphur amino acids in adults over the age of 60 years: the total sulphur amino acid requirement as methionine only. Methionine is an essential amino acid. the minimum methionine requirement as methionine in the presence of excess dietary cysteine. It is …

Accepts healthy volunteers
  • 0 views
  • 25 Mar, 2022
  • 1 location
Clinical Comparison of Topical Application of Alvogyl Versus Hyaluronic-Acid Gel in Management of Pain And Palatal Wound Healing

The aim of the study is to evaluate the effect of application of Alvogyl versus hyaluronic acid in decreasing postoperative pain and promoting healing in the palatal wound following the free gingival graft procedure

Accepts healthy volunteers
  • 0 views
  • 30 Apr, 2022
  • 1 location
Lysophosphatidic Acid / Autotaxin Axis in Rheumatoid Lung Disease

Rheumatoid arthritis (RA) is a common chronic systemic autoimmune relapsing disease characterized by joint inflammation. Beside arthritis leading to progressive joint damage and loss of function, RA is also associated to extraarticular inflammatory conditions such as interstitial lung disease (ILD). This one develops in 30% of all RA patients with …

interstitial lung disease
  • 4 views
  • 05 Aug, 2021
  • 1 location
Chronotherapy of 5-Aminosalicylic Acid in Ulcerative Colitis

The hypothesis of this study is that appropriate time of day of administration of oral, once daily 5-ASA therapy in alignment with the host circadian rhythms will improve subclinical inflammation and microbial structure/function and increase mucosal 5-ASA levels. All subjects will be randomized to once daily 5-ASA medications at two …

  • 0 views
  • 22 Mar, 2022
  • 1 location