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Found 16 clinical trials
Featured trial
  • 174 views
  • 25 Mar, 2021
  • 1 location
Featured trial
A Placebo-controlled, Double-blind, Parallel-group, Bayesian Adaptive Randomization Design and Dose Regimen-finding Study to Evaluate Safety, Tolerability and Efficacy of BAN2401 in Subjects With Early Alzheimer's Disease

A Placebo-controlled, Double-blind, Parallel-group, Bayesian Adaptive Randomization Design and Dose Regimen-finding Study to Evaluate Safety, Tolerability and Efficacy of BAN2401 in Subjects With Early Alzheimer's Disease

  • 258 views
  • 08 Dec, 2020
  • 1 location
The Effect of Guanfacine on Delirium in Critically Ill Patients

cost, increased ventilator days, and long-term cognitive disability. Various pharmacologic agents including dopamine antagonists, acetylcholinesterase inhibitors, melatonin, antipsychotics, alpha-2

  • 17 views
  • 26 Nov, 2021
  • 1 location
Comparative Efficacy and Safety of Sugammadex and Neostigmine

the endotrachea tube. Traditionally, acetylcholinesterase inhibitor (AChEI, such as neostigmine, pyridostigmine, edrophonium) is used to reverse the efficacy of NMBA and stabilize the

  • 40 views
  • 10 Sep, 2021
  • 1 location
Enhancing Parasympathetic Activity to Improve Endothelial Dysfunction, Vascular Oxidative Stress in African Americans

Specific Aim 1: To test the hypothesis that prolonged (3-month) treatment with galantamine inhibits NADPH IsoLG-protein adducts formation and improves markers of endothelial cell (EC) dysfunction in AAs. Aim 1a: The investigators will determine if galantamine inhibits NADPH IsoLG-protein adducts formation, superoxide production, and immune cell activation compared to placebo. …

Accepts healthy volunteers
  • 0 views
  • 02 Jan, 2022
  • 2 locations
The Effect of Donepezil on Wound Healing

The purpose of the study is to test effectiveness of donepezil to improve wound healing in patients with diabetic wounds that have not healed with standard treatment.

  • 0 views
  • 30 Oct, 2021
  • 1 location
Efficiency of Donepezil in Elderly Patients for Prevention of POCD Dysfunction

method was proved. According to our previous study, the central cholinergic system impaired by the anesthesia and surgery play a very important role in the POCD and donepezil an acetylcholinesterase

anesthesia
total knee replacement
  • 0 views
  • 28 Jan, 2021
  • 1 location
Effect of Hydralazine on Alzheimer's Disease (EHSAN)

one of the acetylcholinesterase inhibitor (AChEI) donepezil, rivastigmine, or galantamine.

donepezil
acetylcholinesterase inhibitor
mental state examination
acetylcholinesterase
alzheimer's disease
  • 0 views
  • 21 Mar, 2022
  • 1 location
The Role of Acupuncture-induced Exosome in Treating Post-stroke Dementia

dementia is memory and cognitive impairment. At present, acetylcholinesterase inhibitors and NMDA glutamate receptor antagonists, were used for dementia treatment, but those drugs have limited efficacy

  • 0 views
  • 03 May, 2022
  • 1 location
Donepezil for Oxaliplatin-induced Neuropathy Peripheral Neuropathy: Proof of Concept Study (DONEPEZOX)

, no treatment remains univocal for these peripheral neuropathies. But preclinical works have demonstrated that donepezil (acetylcholinesterase inhibitor use for Alzheimer's disease) was able to

  • 0 views
  • 08 Jul, 2022
  • 23 locations