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Found 20 clinical trials
Mechanisms Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 2

angiotensin-converting enzyme (ACE) inhibitor or ARB. After a 48-hour washout, they will undergo a study day in which they are given a single dose of 50 mg LCZ696. They will also receive either the bradykinin

heart failure
vasodilator
ace inhibitor
valsartan
enzyme inhibitors
  • 2 views
  • 24 Jan, 2021
  • 1 location
Oxidative Stress Lowering Effect of Simvastatin and Atorvastatin.

will be stratified for prior ACE-inhibitor use during randomization. All included patients are randomized to treatment with simvastatin 40 mg daily or atorvastatin 10 mg daily to achieve

nephropathy
diabetes
hypertension
type 2 diabetes mellitus
ace inhibitor
  • 91 views
  • 07 Nov, 2020
  • 1 location
Treatment of Angiotensin Converting Enzyme Inhibitor-induced Angioedema

Angiotensin Converting Enzyme (ACE) inhibitors are among the most important and widely prescribed drugs. They reduce the morbidity and mortality associated with high blood pressure, heart disease, and kidney disease. Unfortunately, their use carries the risk of causing life-threatening airway swelling in some patients. There is currently no treatment for …

  • 0 views
  • 27 Jan, 2021
  • 1 location
Evaluation of a Renin Inhibitor Aliskiren Compared to Enalapril in C3 Glomerulopathy

The aim of this cross-over trial is to assess aliskiren, a direct renin inhibitor, as a novel treatment to block complement activation in the kidneys and thereby attenuate renal disease and stabilize or improve kidney function and compare it to the currently used treatment with the angiotensin converting enzyme inhibitor, …

mammogram
enzyme inhibitor
kidney biopsy
  • 0 views
  • 26 Jan, 2021
  • 4 locations
ACES - ACE Inhibitors Combined With Exercise for Seniors With Hypertension

The purpose of this project is to conduct a randomized, controlled trial (RCT) to determine if choice of antihypertensive medication influences changes in functional status and other cardiovascular risk factors among older persons with hypertension when combined with physical exercise.

aerobic exercise
ace inhibitor
blood pressure diastolic
hydrochlorothiazide
antihypertensive drugs
  • 164 views
  • 23 Jan, 2021
  • 3 locations
PITA-HF: Feasibility Safety and Tolerability

Heart failure affects over 25 million people worldwide and nearly 7 million adults in the United States alone. Nearly 25% of patients with heart failure have worsened disease burden from dyssynchronous ventricular contraction due to abnormal electrical impulse propagation. These patients may benefit from cardiac resynchronization therapy (CRT) where contraction …

  • 0 views
  • 27 Jan, 2021
  • 1 location
Stopping ACE-inhibitors in COVID-19

ACEI-COVID-19 is a multicenter, randomized trial testing the hypothesis that stopping/replacing chronic treatment with ACE-inhibitors (ACEI) or angiotensin receptor blockers (ARB) improves outcomes in symptomatic SARS-CoV2-infected patients

ace inhibitor
covid-19
angiotensin
SARS
  • 40 views
  • 25 Jan, 2021
  • 25 locations
Influenza Vaccination ACEI and ARB in the Evolution of SARS-Covid19 Infection

Some authors have proposed the use of the flu vaccine to reduce the severity of COVID-19 cases, while some have proposed the use of ACE Inhibitors (ACEI) or Angiotensin Receptor blockers (ARB), since this virus shares hemagglutinin as a transmission mechanism and acts on the ACE2 enzyme during infection. The …

ace inhibitor
angiotensin
SARS
  • 0 views
  • 25 Jan, 2021
  • 1 location
Evaluation and Management of Cardio Toxicity in Oncologic Patients

addition of angiotensin-converting-enzyme inhibitor (ACE inhibitor) and beta blockers to the patient's treatment may prevent the development of cardiac dysfunction. However, currently there are no specific

heart failure
troponin
cancer
ace inhibitor
enzyme inhibitors
  • 1 views
  • 24 Jan, 2021
  • 1 location
Multimodal IMAgery Characterization of Cardiac Damage and Severity After COVID-19 Infection

ACE inhibitor, beta-blockers, steroids...? ) In this study, the investigators proposed to collect multimodal cardiac imaging including MRI (Magnetic Resonance Imaging) and TTE (Transthoracic

  • 0 views
  • 23 Feb, 2021
  • 1 location