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Found 19 clinical trials
Study of Optimal Treatment Plan in Hypertensives With Anti-AT1-Receptor Autoantibody

hypertension were recruited and ATR-AA was assayed by ELISA. A study was carried out and the efficacy of anti-hypertension was compared between candesartan cilexetil and ACE inhibitor imidapril.

ATR
ace inhibitor
candesartan
  • 3 views
  • 07 Nov, 2020
  • 1 location
Study of Endothelial Dysfunction in Systemic Lupus and Its Role in Heart Disease

reverse abnormalities in endothelial function and myocardial perfusion by therapy with an ACE inhibitor(Quinapril).Patients with myocardial perfusion abnormalities will be randomised to receive

heart disease
ace inhibitor
autoimmune disease
cardiovascular disease
  • 27 views
  • 07 Nov, 2020
  • 1 location
Acute Haemodynamic Effects of Treatment With Angiotensin Converting Enzyme (ACE)-Inhibitors in Patients With Symptomatic Aortic Stenosis

Abundant evidence suggests that Angiotensin Converting Enzyme (ACE) inhibition potentially could reduce the hazardous effects of aortic stenosis and improve haemodynamics. The treatment seems safe even in patients with severe stenosis. There are however no randomised clinical trials that can confirm this hypothesis.

symptomatic aortic stenosis
syncope
angina pectoris
  • 0 views
  • 07 Nov, 2020
  • 1 location
A Crossover Pilot Study of the Effect of Amiloride on Proteinuria

This cross-over study is designed to test the hypothesis that amiloride will reduce urinary protein excretion and protect the kidney from rapid progression in proteinuric kidney disease.

glomerular filtration rate
nephropathy
  • 3 views
  • 23 Jan, 2021
  • 2 locations
S1501 Carvedilol in Preventing Cardiac Toxicity in Patients With Metastatic HER-2-Positive Breast Cancer

This phase III trial studies how well carvedilol works in preventing cardiac toxicity in patients with human epidermal growth factor receptor (HER)-2-positive breast cancer that has spread to other places in the body. A beta-blocker, such as carvedilol, is used to treat heart failure and high blood pressure, and it …

oophorectomy
erbb2
trastuzumab
brain metastases
step 2
  • 200 views
  • 27 Nov, 2020
  • 118 locations
Host Response Mediators in Coronavirus (COVID-19) Infection - Is There a Protective Effect of Losartan on Outcomes of Coronavirus Infection?

SARS-CoV-2 is a member of a class of viruses: angiotensin converting enzyme 2 (ACE2)-binding viruses that we call "ABVs". The World Health Organization (WHO) and others are performing randomized controlled trials (RCTs) of vaccines and novel antivirals to address SARS-CoV-2 directly. However, the critical illness complications of COVID-19 are caused …

  • 12 views
  • 04 Nov, 2020
  • 18 locations
Renin-angiotensin System Blockade Benefits in Clinical Evolution and Ventricular Remodeling After Transcatheter Aortic Valve Implantation (RASTAVI)

The investigators aim to demonstrate that ramipril after transcatheter aortic valve implantation has benefits in terms of prognosis, cardiovascular events and ventricular remodeling (MRI).

  • 0 views
  • 23 Jan, 2021
  • 2 locations
Left Atrial Remodelling in Hypertension: Effects of Ramipril or Irbesartan

Aim of the study is to compare in hypertensive patients the effect of one year therapy with ACE-inhibitor (RAMIPRIL) or angiotensin II receptor blocker (IRBESARTAN) on left atrial

  • 5 views
  • 07 Nov, 2020
  • 1 location
A Study of the Safety Tolerability Pharmacokinetics and Efficacy of Treatment With AP1189 in Patients With iMN

membranous nephropathy (iMN) who are on ACE inhibitor or angiotensin II receptor blocker treatment.

ace inhibitor
protein creatinine ratio
nephrotic syndrome
angiotensin
kidney biopsy
  • 0 views
  • 25 Jan, 2021
  • 1 location
The Effect of Ramipril in Suppressing ST2 Expression in Rheumatic Mitral Stenosis Patients

Objective propose: to investigate the effect of Ramipril in suppressing ST2 (suppression of tumorigenicity 2) in the cardiac mitral valve in patients with Rheumatic Heart Disease. We hypothesized that we hypothesized that ramipril will improve rheumatic mitral valve fibrosis through the downregulation of ST2.

tricuspid valve repair
stenosis
heart disease
rheumatic heart disease
  • 110 views
  • 16 Dec, 2020
  • 1 location