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Found 22 clinical trials
Study of Optimal Treatment Plan in Hypertensives With Anti-AT1-Receptor Autoantibody

hypertension were recruited and ATR-AA was assayed by ELISA. A study was carried out and the efficacy of anti-hypertension was compared between candesartan cilexetil and ACE inhibitor imidapril.

candesartan
ace inhibitor
ATR
  • 3 views
  • 07 Nov, 2020
  • 1 location
Study of Endothelial Dysfunction in Systemic Lupus and Its Role in Heart Disease

reverse abnormalities in endothelial function and myocardial perfusion by therapy with an ACE inhibitor(Quinapril).Patients with myocardial perfusion abnormalities will be randomised to receive

cardiovascular disease
ace inhibitor
autoimmune disease
heart disease
  • 27 views
  • 07 Nov, 2020
  • 1 location
A Crossover Pilot Study of the Effect of Amiloride on Proteinuria

This cross-over study is designed to test the hypothesis that amiloride will reduce urinary protein excretion and protect the kidney from rapid progression in proteinuric kidney disease.

nephropathy
glomerular filtration rate
  • 3 views
  • 23 Jan, 2021
  • 2 locations
Acute Haemodynamic Effects of Treatment With Angiotensin Converting Enzyme (ACE)-Inhibitors in Patients With Symptomatic Aortic Stenosis

Abundant evidence suggests that Angiotensin Converting Enzyme (ACE) inhibition potentially could reduce the hazardous effects of aortic stenosis and improve haemodynamics. The treatment seems safe even in patients with severe stenosis. There are however no randomised clinical trials that can confirm this hypothesis.

symptomatic aortic stenosis
angina pectoris
syncope
  • 0 views
  • 07 Nov, 2020
  • 1 location
S1501 Carvedilol in Preventing Cardiac Toxicity in Patients With Metastatic HER-2-Positive Breast Cancer

This phase III trial studies how well carvedilol works in preventing cardiac toxicity in patients with human epidermal growth factor receptor (HER)-2-positive breast cancer that has spread to other places in the body. A beta-blocker, such as carvedilol, is used to treat heart failure and high blood pressure, and it …

ejection fraction
ceritinib
trastuzumab
growth factor
step 2
  • 200 views
  • 24 May, 2021
  • 120 locations
Learning Implementation of Guideline-based Decision Support System for Hypertension Treatment: Testing Alternative Antihypertensive Regimens Using ACE-Inhibitors Calcium Channel Blockers and Diuretics (LIGHT-ACD)

This trial aims to compare the efficacy of several guideline-based hypertensive medication regimens initiated with Angiotensin Converting Enzyme Inhibitor/Angiotensin Receptor Blocker [A], Calcium Channel Blocker [C] and Diuretic [D].

calcium channel blockers
calcium
angiotensin converting enzyme
angiotensin
essential hypertension
  • 0 views
  • 25 Apr, 2021
  • 3 locations
Renin-angiotensin System Blockade Benefits in Clinical Evolution and Ventricular Remodeling After Transcatheter Aortic Valve Implantation (RASTAVI)

The investigators aim to demonstrate that ramipril after transcatheter aortic valve implantation has benefits in terms of prognosis, cardiovascular events and ventricular remodeling (MRI).

  • 0 views
  • 23 Jan, 2021
  • 2 locations
Left Atrial Remodelling in Hypertension: Effects of Ramipril or Irbesartan

Aim of the study is to compare in hypertensive patients the effect of one year therapy with ACE-inhibitor (RAMIPRIL) or angiotensin II receptor blocker (IRBESARTAN) on left atrial

  • 5 views
  • 07 Nov, 2020
  • 1 location
A Study of the Safety Tolerability Pharmacokinetics and Efficacy of Treatment With AP1189 in Patients With iMN

membranous nephropathy (iMN) who are on ACE inhibitor or angiotensin II receptor blocker treatment.

angiotensin
ace inhibitor
kidney biopsy
nephrotic syndrome
protein creatinine ratio
  • 0 views
  • 25 Jan, 2021
  • 1 location
The Effect of Ramipril in Suppressing ST2 Expression in Rheumatic Mitral Stenosis Patients

Objective propose: to investigate the effect of Ramipril in suppressing ST2 (suppression of tumorigenicity 2) in the cardiac mitral valve in patients with Rheumatic Heart Disease. We hypothesized that we hypothesized that ramipril will improve rheumatic mitral valve fibrosis through the downregulation of ST2.

stenosis
heart disease
tricuspid valve repair
rheumatic heart disease
mitral valve replacement
  • 110 views
  • 23 Aug, 2021
  • 1 location