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Found 912 clinical trials
Oxytocin to Reduce Stress-induced Craving in Individuals With Opioid Use Disorder (OSCO)

Although stress has long been linked to substance use, craving and relapse, there are no available medications that target stress-induced substance use disorder (SUD). In particular, with the

buprenorphine
substance use
narcotic use
opiates
oxytocin
  • 90 views
  • 18 Oct, 2022
  • 1 location
Biomarker Validation in Motor System Physiology in Attention Deficit Hyperactivity Disorder (AMPAIII)

high levels of impulsivity and hyperactivity. They are at substantially increased risk for long-term difficulties into adulthood, including academic underachievement, substance abuse, and criminal

Accepts healthy volunteers
  • 0 views
  • 27 Jun, 2022
  • 2 locations
Effects of MDMA-like Substances in Healthy Subjects

abuse. Additionally, blood pressure may increase rapidly at drug onset. A possible solution to mitigate anxiety, abuse-related rapid euphoria increases and/or rapid blood pressure changes at onset

Accepts healthy volunteers
  • 50 views
  • 05 Jan, 2022
  • 1 location
Cocaine and Zolmitriptan

subtypes have been implicated in the abuse-related effects of cocaine, including its primary reinforcing effects (i.e., cocaine taking behavior). 5-HT1b receptors, which are autoreceptors on 5-HT nerve

Accepts healthy volunteers
  • 0 views
  • 16 Jun, 2022
  • 1 location
Development of Neuroimaging Methods to Assess the Neurobiology of Addiction

alcoholism or drug abuse. Participants will answer questions to see if they can participate in MRI. Participants will have MRI scans. The scanner is a metal cylinder in a strong magnetic field

Accepts healthy volunteers
  • 572 views
  • 25 Oct, 2022
  • 1 location
Neurocognitive Factors in Substance Use Treatment Response: The Ways of Rewarding Abstinence Project (WRAP)

substance use treatment planning. Substance use disorders are prevalent amongst Veterans. Cocaine addiction, in particular, has been shown to complicate treatment of other high priority behavioral health

  • 1 views
  • 20 Feb, 2022
  • 1 location
rTMS, Stress and Opioid Use Disorder (TOTS)

trying to recover from substance use disorders (SUDs) because it weakens inhibition of automatic behaviors and increases drug craving and likelihood of relapse. However, paths through which stress

  • 0 views
  • 12 May, 2022
  • 1 location
Intermittent Oral Naltrexone Enhanced With an Ecological Momentary Intervention for Methamphetamine-using MSM

enhanced with an EMA-informed EMI platform, or receive as-needed placebo with EMA-informed EMI. The 12-week treatment period is consistent with other pharmacotherapy trials for substance use disorders. The

Accepts healthy volunteers
  • 0 views
  • 07 Oct, 2022
  • 1 location
Effect of Vestibular Rehabilitation Therapy on Patients With Brain Radiological Findings That Affect Balance Functions

adaptation, substitution by the other eye-movement systems, substitution by vision, somatosensory cues, other postural strategies, and habituation .

  • 0 views
  • 13 Oct, 2022
  • 1 location
The Effect of Intravenous Ketamine on Non Suicidal Self Injuries.

of intravenous ketamine in decreasing NSSI symptomology in women with a history of childhood sexual abuse presenting with such behavior. Participants will be recruited among hospitalized patients

  • 6 views
  • 25 Feb, 2022
  • 1 location