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Found 37 clinical trials
Featured trial
CTLA4-Ig (Abatacept)for Prevention of Abnormal Glucose Tolerance and Diabetes in Relatives At -Risk for Type 1 Diabetes

CTLA4-Ig (Abatacept)for Prevention of Abnormal Glucose Tolerance and Diabetes in Relatives At -Risk for Type 1 Diabetes

  • 286 views
  • 25 Mar, 2021
  • 1 location
Featured trial
(OSKIRA): A Phase III, Multi-centre, Randomised, Double-Blind, Placebo-Controlled, Parallel Group Study of Two Dosing Regimens of Investigational Product (Oral Agents) in Rheumatoid Arthritis Patients.

(OSKIRA): A Phase III, Multi-centre, Randomised, Double-Blind, Placebo-Controlled, Parallel Group Study of Two Dosing Regimens of Investigational Product (Oral Agents) in Rheumatoid Arthritis Patients.

  • 178 views
  • 08 Nov, 2020
  • 1 location
None
Abatacept Conversion in Kidney Transplantation

infusions to abatacept subcutaneous injections without a decrease in kidney function.The primary objective will be the difference in estimated GFR (eGFR) for abatacept and belatacept groups using a monthly

  • 0 views
  • 05 Oct, 2021
None
Abatacept Bone Effects in Psoriatic Arthritis With Bone Biomarker

in arthritis [Krabben A, 2013]. Abatacept with its favourable safety profile preferentially interrupts activation of nave T cells and perhaps makes the strongest case for exploiting co-stimulatory

  • 2 views
  • 24 Jan, 2021
None
Abatacept for Treatment of Recurrent or de Novo Autoimmune Hepatitis

The purpose of this study is to evaluate whether Orencia (Abatacept) improves outcomes in liver transplant patients with recurrent or de novo AIH (autoimmune hepatitis) that has not responded to

liver disease
liver damage
immunosuppressive agents
liver transplant
abatacept
  • 2 views
  • 31 Mar, 2021
  • 1 location
None
Ustekinumab for the Treatment of Relapse of Refractory Giant Cell Arteritis

, abatacept and tocilizumab have been shown to be effective during GCA. However, the therapeutic effect of the first two is modest. As for tocilizumab, its use has many limitations: suspensive effect, many

  • 0 views
  • 25 Jan, 2021
  • 1 location
None
Combination of Baricitinib and Adalimumab in Rheumatoid Arthritis

(RCTs) have explored the efficacy and safety of combining tumour necrosis factor (TNF) inhibitor with another biologic (anakinra, abatacept, rituximab or bimekizumab). Baricitinib is a selective

tumour necrosis
rheumatism
prednisone
anakinra
baricitinib
  • 0 views
  • 21 Jul, 2021
  • 20 locations
None
Abatacept for the Treatment of Relapsing Non-Severe Granulomatosis With Polyangiitis (Wegener's)

Multi-center, randomized, double-blind, placebo-controlled trial to evaluate the efficacy of abatacept to achieve sustained glucocorticoid-free remission in patients with relapsing non-severe

urinary sediment
anti-neutrophil cytoplasmic antibody
nasal discharge
granulomatous inflammation
norplant
  • 197 views
  • 28 Apr, 2021
  • 26 locations
None
Study to Assess Safety and Effectiveness of Branebrutinib Treatment in Participants With Active Systemic Lupus Erythematosus or Primary Sj gren's Syndrome or Branebrutinib Treatment Followed by Open-label Abatacept Treatment in Study Participants With Active Rheumatoid Arthritis

Syndrome (pSS), or branebrutinib treatment followed by open-label abatacept treatment in study participants with active Rheumatoid Arthritis (RA).

arthritis
sjogren's syndrome
lupus
progressive systemic sclerosis
abatacept
  • 328 views
  • 27 Oct, 2021
  • 1 location
None
Cyclophosphamide Abatacept and Tacrolimus for GvHD Prevention

, abatacept, and short-duration tacrolimus for GvHD prophylaxis.

tacrolimus
cyclophosphamide
carbon monoxide diffusing capacity
ejection fraction
carbon monoxide
  • 0 views
  • 11 Jul, 2021
  • 1 location