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Found 39 clinical trials
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(OSKIRA): A Phase III, Multi-centre, Randomised, Double-Blind, Placebo-Controlled, Parallel Group Study of Two Dosing Regimens of Investigational Product (Oral Agents) in Rheumatoid Arthritis Patients.

(OSKIRA): A Phase III, Multi-centre, Randomised, Double-Blind, Placebo-Controlled, Parallel Group Study of Two Dosing Regimens of Investigational Product (Oral Agents) in Rheumatoid Arthritis Patients.

  • 204 views
  • 08 Nov, 2020
  • 1 location
A Study to Compare the Response to Treatment With Abatacept vs Adalimumab, on Background Methotrexate, in Adults With Early, Seropositive, and Shared Epitope-positive Rheumatoid Arthritis and an Inadequate Response to Methotrexate

The purpose of this study is to evaluate the superiority in efficacy of abatacept compared with adalimumab, on background methotrexate, in adults with early, seropositive, and shared epitope

methotrexate
adalimumab
cyclic citrullinated peptide antibody
antirheumatics
rheumatoid factor
  • 0 views
  • 17 May, 2022
  • 25 locations
Abatacept Conversion in Kidney Transplantation

infusions to abatacept subcutaneous injections without a decrease in kidney function.The primary objective will be the difference in estimated GFR (eGFR) for abatacept and belatacept groups using a monthly

  • 0 views
  • 05 Oct, 2021
Abatacept Bone Effects in Psoriatic Arthritis With Bone Biomarker

in arthritis [Krabben A, 2013]. Abatacept with its favourable safety profile preferentially interrupts activation of nave T cells and perhaps makes the strongest case for exploiting co-stimulatory

  • 2 views
  • 24 Jan, 2021
EFFECTS OF ABATACEPT on the Progression to Rheumatoid Arthritis(PALABA Study) (PALABA)

The main objective of this trial is to test the hypothesis that abatacept can reduce the progression of rheumatoid arthritis in ACPA+ or RF+ patients with palindromic rheumatism compared with

  • 0 views
  • 19 Apr, 2022
  • 1 location
Ustekinumab for the Treatment of Relapse of Refractory Giant Cell Arteritis (ULTRA)

, abatacept and tocilizumab have been shown to be effective during GCA. However, the therapeutic effect of the first two is modest. As for tocilizumab, its use has many limitations: suspensive effect, many

  • 0 views
  • 26 Apr, 2022
  • 1 location
Combination of Baricitinib and Adalimumab in Rheumatoid Arthritis (CRI-RA)

(RCTs) have explored the efficacy and safety of combining tumour necrosis factor (TNF) inhibitor with another biologic (anakinra, abatacept, rituximab or bimekizumab). Baricitinib is a selective

tumor necrosis factor
prednisone
corticosteroids
DMARD
methotrexate
  • 0 views
  • 15 Mar, 2022
  • 6 locations
Abatacept for the Treatment of Relapsing, Non-Severe, Granulomatosis With Polyangiitis (Wegener's)

Multi-center, randomized, double-blind, placebo-controlled trial to evaluate the efficacy of abatacept to achieve sustained glucocorticoid-free remission in patients with relapsing non-severe

churg-strauss syndrome
anca
cavities
tooth decay
nasal discharge
  • 197 views
  • 18 May, 2022
  • 20 locations
Study to Assess Safety and Effectiveness of Branebrutinib Treatment in Participants With Active Systemic Lupus Erythematosus or Primary Sjögren's Syndrome, or Branebrutinib Treatment Followed by Open-label Abatacept Treatment in Study Participants With Active Rheumatoid Arthritis

Sjögren's Syndrome (pSS), or branebrutinib treatment followed by open-label abatacept treatment in study participants with active Rheumatoid Arthritis (RA).

lupus
progressive systemic sclerosis
abatacept
arthritis
sjogren's syndrome
  • 394 views
  • 12 May, 2022
  • 63 locations
Cyclophosphamide, Abatacept, and Tacrolimus for GvHD Prevention

, abatacept, and short-duration tacrolimus for GvHD prophylaxis.

hematologic malignancy
fungal infection
ejection fraction
carbon monoxide
tacrolimus
  • 0 views
  • 16 May, 2022
  • 1 location